Abstract: A warhead fuse mechanism is used to prevent an accidental explosive event of a warhead by positioning a booster lead carrier, having a booster lead segment, positioned between the warhead detonator and warhead explosive. In a safe position the booster lead segment is off-set from alignment with the warhead detonator and warhead explosive. The warhead fuse is armed by rotating either the warhead detonator or booster lead carrier to align the warhead detonator and booster lead segment to form a detonation chain between the warhead detonator and warhead explosive.

Abstract: 6,7-Dihydro-5H-cyclopenta[b]pyridine and 5,6,7,8-tetrahydroquinoline compounds of Formula (I), including salts, hydrates and solvates thereof, that act as 5-HT2 receptor ligands and their uses in the treatment of diseases linked to the activation of 5-HT2c receptors are described herein.

Abstract: A medical or surgical device or tool that is designed to be implanted or inserted inside the human or mammalian body, having at least part of its surface coated whereby the ultrasound visibility of said device or tool in vivo is enhanced, wherein the coating comprises one or more of the following: (i) a matrix material containing a plurality of contrast enhancing elements; (ii) magnesium; (iii) a liquid or polymer which alters its ultrasound imaging properties upon elevating the temperature from ambient to physiological temperature; (iv) a liquid or polymer which alters its ultrasound imaging properties as a result of a change in pH; (v) an essentially non-polymeric bio-compatible compound which forms a discontinuous coating. Preferably the device or tool is a radioactive source for use in brachytherapy, and in particular a radioactive seed.