Abstract: A smoke evacuation device that evacuates smoke from a surgical site and filters the smoke from the air. The smoke evacuation device can include a fluid trap for removing moisture from the smoke. The smoke evacuation device can also include a filter with a compression mechanism for compressing a filter medium. The smoke evacuation device can also include features for controlling flow parameters, noise, and vibrations of the device. A remote activation device can also be used to activate the smoke evacuation device upon detection of certain system parameters.

Abstract: A smoke evacuation device that evacuates smoke from a surgical site and filters the smoke from the air. The smoke evacuation device can include a fluid trap for removing moisture from the smoke. The smoke evacuation device can also include a filter with a compression mechanism for compressing a filter medium. The smoke evacuation device can also include features for controlling flow parameters, noise, and vibrations of the device. A remote activation device can also be used to activate the smoke evacuation device upon detection of certain system parameters.

Abstract: A filter connection for a smoke evacuation device includes a filter canister assembly and a socket. The filter canister assembly has a cross-sectional shape with only one line of symmetry that corresponds to a cross-sectional shape of the socket so that the filter canister can only be inserted into the socket in one orientation. One or more key notches on the filter canister may also ensure that the filter is properly installed. A seal creates an airtight boundary between the filter canister and a recess of the socket so that a sealed path in communication with the smoke evacuation device is established before the filter canister is fully inserted into the socket. An electronic connection is made between the filter canister and the socket after the airtight boundary is created.

Abstract: A filter connection for a smoke evacuation device includes a filter canister assembly and a socket. The filter canister assembly has a cross-sectional shape with only one line of symmetry that corresponds to a cross-sectional shape of the socket so that the filter canister can only be inserted into the socket in one orientation. One or more key notches on the filter canister may also ensure that the filter is properly installed. A seal creates an airtight boundary between the filter canister and a recess of the socket so that a sealed path in communication with the smoke evacuation device is established before the filter canister is fully inserted into the socket. An electronic connection is made between the filter canister and the socket after the airtight boundary is created.

Abstract: A filter connection for a smoke evacuation device includes a filter canister assembly and a socket. The filter canister assembly has a cross-sectional shape with only one line of symmetry that corresponds to a cross-sectional shape of the socket so that the filter canister can only be inserted into the socket in one orientation. One or more key notches on the filter canister may also ensure that the filter is properly installed. A seal creates an airtight boundary between the filter canister and a recess of the socket so that a sealed path in communication with the smoke evacuation device is established before the filter canister is fully inserted into the socket. An electronic connection is made between the filter canister and the socket after the airtight boundary is created.

Abstract: A smoke evacuation device that evacuates smoke from a surgical site and filters the smoke from the air. The smoke evacuation device can include a fluid trap for removing moisture from the smoke. The smoke evacuation device can also include a filter with a compression mechanism for compressing a filter medium. The smoke evacuation device can also include features for controlling flow parameters, noise, and vibrations of the device. A remote activation device can also be used to activate the smoke evacuation device upon detection of certain system parameters.

Abstract: A filter connection for a smoke evacuation device includes a filter canister assembly and a socket. The filter canister assembly has a cross-sectional shape with only one line of symmetry that corresponds to a cross-sectional shape of the socket so that the filter canister can only be inserted into the socket in one orientation. One or more key notches on the filter canister may also ensure that the filter is properly installed. A seal creates an airtight boundary between the filter canister and a recess of the socket so that a sealed path in communication with the smoke evacuation device is established before the filter canister is fully inserted into the socket. An electronic connection is made between the filter canister and the socket after the airtight boundary is created.

Abstract: Compounds of Formula (I): in which R1, R2, R3, R4, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor.