Patents by Inventor Steven D. Dong

Steven D. Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Esters of compounds in the leptomycin family
    Patent number: 8003687
    Abstract: Esters of compounds in the leptomycin family, having a structure according to formula I where R, R10, R11, R12, R13, and R14 are as defined herein, exhibit anti-tumor properties.
    Type: Grant
    Filed: September 11, 2006
    Date of Patent: August 23, 2011
    Assignee: Kosan Biosciences Incorporated
    Inventors: Steven D. Dong, Daniel V. Santi
  • Esters of Compounds in the Leptomycin Family
    Publication number: 20100222382
    Abstract: Esters of compounds in the leptomycin family, having a structure according to formula I where R, R10, R11, R12, R13, and R14 are as defined herein, exhibit anti-tumor properties.
    Type: Application
    Filed: September 11, 2006
    Publication date: September 2, 2010
    Applicant: Kosan Biosciences Incorporated
    Inventors: Steven D Dong, Daniel V. Santi
  • Leptomycin compounds
    Patent number: 7655808
    Abstract: Leptomycin-type compounds according to formula I wherein R0, R1, R2, R10, R11, R12, R13, R14, and m are as defined herein, exhibit anti-tumor activity.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: February 2, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Steven D. Dong, Daniel V. Santi, David C. Myles, Brian Hearn
  • Sixteen-membered macrolide compounds
    Publication number: 20020128213
    Abstract: The present invention provides novel sixteen-membered macrolide compounds that are useful as anti-infective agents or as intermediates thereto. The present invention also provides methods for the preparation of these compounds, and methods and formulations for their use. In one aspect of the present invention, sixteen-membered macrolide possessing a side chain Z are provided where Z is aliphatic, aryl, alkylaryl, halide, ═NOR3, ═NNHR3, or —W—R3 where W is O, S, NC(═O)R4, NC(═O)OR4, NC(═O)NHR4 or NR4 where R3 and R4 are each independently hydrogen, aliphatic, aryl or alkylaryl. In another aspect of the present invention, bicyclic compounds are provided where one of the cyclic-components is a sixteen-membered macrolide and the other is a cyclic moiety whose cyclic structure is formed by between 3 and 10 atoms. In another aspect of the present invention, sixteen-membered macrolide compounds that bind to the domain II region of the 23S RNA are provided.
    Type: Application
    Filed: September 24, 2001
    Publication date: September 12, 2002
    Inventors: Leonard Katz, Gary Ashley, Mark A. Burlingame, Steven D. Dong, Hong Fu, Yong Li, David C. Myles