Patents by Inventor Steven D. Weitman

Steven D. Weitman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methodology of using raman imaging microscopy for evaluating drug action within living cells
    Patent number: 6939686
    Abstract: A method of using Raman imaging microscopy to evaluate drug actions in living cells is disclosed. Specifically the invention describes the methods of using Raman imaging microscopy to detect drug uptake, distribution, binding, and metabolism in a single cell, and to study drug pharmacokinetics at the cellular level. The method involves measuring the Raman image of both the drug and the cell. Control images and post-treatment images of the cell were studied. Ratio images were calculated and the requisite information was obtained from a study of the intensity of the bright areas in the ratio images.
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: September 6, 2005
    Assignee: Southwest Research Institute
    Inventors: Jian Ling, Steven D. Weitman, Michael A. Miller
  • Methodology of using Raman imaging microscopy for evaluating drug action within living cells
    Publication number: 20040157208
    Abstract: A method of using Raman imaging microscopy to evaluate drug actions in living cells is disclosed. Specifically the invention describes the methods of using Raman imaging microscopy to detect drug uptake, distribution, binding, and metabolism in a single cell, and to study drug pharmacokinetics at the cellular level. The method involves measuring the Raman image of both the drug and the cell. Control images and post-treatment images of the cell were studied. Ratio images were calculated and the requisite information was obtained from a study of the intensity of the bright areas in the ratio images.
    Type: Application
    Filed: December 31, 2003
    Publication date: August 12, 2004
    Inventors: Jian Ling, Steven D. Weitman, Michael A. Miller
  • MUC1 interference RNA compositions and methods derived therefrom
    Publication number: 20040018181
    Abstract: The present invention provides compositions and methods for inhibiting the proliferation of cancer cells and for the treatment of tumors with antagonists of the binding of ligands to the extracellular domain of MUC1, such binding being related to an oncogenic function of MUC1, and by compositions that downregulate the expression of MUC1.
    Type: Application
    Filed: May 29, 2003
    Publication date: January 29, 2004
    Inventors: Donald W. Kufe, Surender Kharbanda, Steven D. Weitman
  • Methodology of using raman imaging microscopy for evaluating drug action within living cells
    Publication number: 20010044129
    Abstract: A method of using Raman imaging microscopy to evaluate drug actions in living cells is disclosed. Specifically the invention describes the methods of using Raman imaging microscopy to detect drug uptake, distribution, binding, and metabolism in a single cell, and to study drug pharmacokinetics at the cellular level. The method involves measuring the Raman image of both the drug and the cell. Control images and post-treatment images of the cell were studied. Ratio images were calculated and the requisite information was obtained from a study of the intensity of the bright areas in the ratio images.
    Type: Application
    Filed: March 13, 2001
    Publication date: November 22, 2001
    Inventors: Jian Ling, Steven D. Weitman, Michael A. Miller
  • Method for drug administration
    Patent number: 4792449
    Abstract: This invention relates to a method for administering drugs. In particular a lipophilic drug is solubilized by a food, such as chocolate, and admixed with an oil-based carrier. The lipid soluble drug is thus conveyed to the gastrointestinal tract. Because this type of food is digested readily, the drug is absorbed as intended, and the dose is not subject to day-to-day variations.
    Type: Grant
    Filed: January 28, 1987
    Date of Patent: December 20, 1988
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Robert K. Ausman, Mark Adams, Gerado Caballero, Rahim Hamid, Norman E. Hoffman, Edward J. Quebbeman, William J. Schulte, Robert Thomson, Julie Whipple, Steven D. Weitman