Patents by Inventor Steven Dabbs

Steven Dabbs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antagonists acting at multiple prostaglandin receptors for the treatment of inflammation
    Patent number: 9657018
    Abstract: Compounds, processes for their preparation, pharmaceutical compositions containing such compounds and their use in treating therapeutic conditions, in particular conditions mediated by the action of ligands on the FP, DP, EP1, EP4, IP, DP1, FP and TP prostaglandin (PG) receptors thereby providing a general anti-inflammatory response.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: May 23, 2017
    Assignee: ALLERGAN, INC.
    Inventors: Jose L. Martos, David F. Woodward, Jenny W. Wang, Steven Dabbs, Jussi J. Kangasmetsa
  • ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION
    Publication number: 20170096423
    Abstract: Compounds, processes for their preparation, pharmaceutical compositions containing such compounds and their use in treating therapeutic conditions, in particular conditions mediated by the action of ligands on the FP, DP, EP1, EP4, IP, DP1, FP and TP prostaglandin (PG) receptors thereby providing a general anti-inflammatory response.
    Type: Application
    Filed: May 11, 2016
    Publication date: April 6, 2017
    Inventors: Jose L. Martos, David F. Woodward, Jenny W. Wang, Steven Dabbs, Jussi J. Kangasmetsa
  • Antagonists acting at multiple prostaglandin receptors for the treatment of inflammation
    Patent number: 9365569
    Abstract: Compounds, processes for their preparation, pharmaceutical compositions containing such compounds and their use in treating therapeutic conditions, in particular conditions mediated by the action of ligands on the FP, DP, EP1, EP4, IP, DP1, FP and TP prostaglandin (PG) receptors thereby providing a general anti-inflammatory response.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: June 14, 2016
    Assignee: ALLERGAN, INC.
    Inventors: Jose L. Martos, David F. Woodward, Jenny W. Wang, Steven Dabbs, Jussi J. Kangasmetsa
  • ANTAGONISTS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS FOR THE TREATMENT OF INFLAMMATION
    Publication number: 20150210689
    Abstract: Compounds, processes for their preparation, pharmaceutical compositions containing such compounds and their use in treating therapeutic conditions, in particular conditions mediated by the action of ligands on the FP, DP, EP1, EP4, IP, DP1, FP and TP prostaglandin (PG) receptors thereby providing a general anti-inflammatory response.
    Type: Application
    Filed: January 27, 2015
    Publication date: July 30, 2015
    Inventors: Jose L. Martos, David F. Woodward, Jenny W. Wang, Steven Dabbs, Jussi J. Kangasmetsa
  • Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
    Patent number: 8071592
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: December 6, 2011
    Assignee: Glaxo Group Limited
    Inventors: Lluis Ballell, David Barros, Gerald Brooks, Julia Castro Pichel, Steven Dabbs, Robert A Daines, David Thomas Davies, Jose Maria Fiandor Roman, Israil Pendrak, Modesto J Remuiñan Blanco, Jason Anthony Rossi, Ilaria Giordano, Alan Joseph Hennessy, James B Hoffman, Graham Elgin Jones, Timothy James Miles, Neil David Pearson, Lihua(lily) Zhang
  • TRICYCLIC NITROGEN COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS
    Publication number: 20110009394
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: January 7, 2009
    Publication date: January 13, 2011
    Applicant: Glaxo Group Limited
    Inventors: Pamela Brown, Steven Dabbs, Alan Joseph Hennessy
  • TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS
    Publication number: 20100087424
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: April 17, 2008
    Publication date: April 8, 2010
    Inventors: Pamela Brown, Steven Dabbs
  • COMPOUNDS
    Publication number: 20100056502
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: March 20, 2008
    Publication date: March 4, 2010
    Applicant: GLAXO GROUP LIMITED
    Inventors: Pamela Brown, Steven Dabbs, David Thomas Davies, Neil David Pearson
  • NOVEL POLYMORPH OF (5-AMINO-6-METHOXY-3-PYRIDINCARBONYL) CARBAMIC ACID 2-(S)-HYDROXYMUTILIN 14-ESTER
    Publication number: 20090291987
    Abstract: The present invention relates to a novel polymorph, to processes for the preparation of the polymorph and to the use of the polymorph in medicine, particularly antibacterial therapy.
    Type: Application
    Filed: December 9, 2005
    Publication date: November 26, 2009
    Inventors: Steven Geoffrey Aitken, Steven Dabbs, Eric Hunt
  • DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES
    Publication number: 20090270374
    Abstract: Bicyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: July 18, 2007
    Publication date: October 29, 2009
    Inventors: Llius Ballell, David Barros, Gerald Brooks, Julia Castro Pichel, Steven Dabbs, Robert A. Daines, David Thomas Davies, Jose Maria Fiandor Roman, Israil Pendrak, Modesto J. Remuinan Blanco, Jason Anthony Rossi, Ilaria Giordano, Alan Joseph Hennessy, James B. Hoffman, Graham Elgin Jones, Timothy James Miles, Neil David Pearson, Lihua(lily) Zhang
  • Heterocyclic mutilin esters and their use as antibacterials
    Patent number: 6878704
    Abstract: Pleuromutilin compounds of the formula: are of use in anti-bacterial therapy.
    Type: Grant
    Filed: August 2, 2001
    Date of Patent: April 12, 2005
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Steven Aitken, Gerald Brooks, Steven Dabbs, Colin Henry Frydrych, Steven Howard, Eric Hunt
  • Heterocyclic mutilin esters and their use as antibacterials
    Publication number: 20040058937
    Abstract: Pleuromutilin compounds of the formula: 1
    Type: Application
    Filed: October 17, 2003
    Publication date: March 25, 2004
    Inventors: Steven Aitken, Gerald Brooks, Steven Dabbs, Colin Henry Frydrych, Steven Howard, Eric Hunt
  • Compounds and methods
    Patent number: 6476028
    Abstract: A method of treating a CCR5-mediated disease state in mammals which comprises administering to a mammal in need of such treatment, an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 8, 2000
    Date of Patent: November 5, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: William E. Bondinell, James Chan, Roderick A. Porter, Joseph W. Venslavsky, Steven Dabbs, David T. Davies
  • Pleuromutilin derivatives as antimicrobials
    Patent number: 6281226
    Abstract: The present invention relates to pleuromutilin derivatives, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medical therapy, particularly antibacterial therapy.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: August 28, 2001
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Valerie Berry, Steven Dabbs, Colin Henry Frydrych, Eric Hunt, Francis Dominic Sanderson, Gary Woodnutt
  • Method for synthesis of aryl difluoromethyl ethers
    Patent number: 5731477
    Abstract: This invention relates to a method for preparing difluoromethyl ethers, thiols and amines without using chlorofluorocarbon gases. The intermediates prepared by this method can be used to make certain compounds which act as PDE IV inhibitors which are useful for treating asthma and other diseases implicated with the PDE IV isozyme.
    Type: Grant
    Filed: January 31, 1995
    Date of Patent: March 24, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Joseph M. Karpinski, Siegfried B. Christensen, IV, Steven Dabbs
  • Azabicyclic compounds with muscarinic activity useful for treating dementia
    Patent number: 5470859
    Abstract: A pharmaceutical composition useful to treating dementia which comprises a compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## in which p is 1 and either m is 0 and n is 2 or 3 or m is 1 and n is 2, or p is 2, m is 0 and n is 2, and Z is a heterocyclic group ##STR2## in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one or two heteroatoms selected from oxygen, nitrogen and sulphur, or three nitrogen atoms, any amino nitrogen being substituted by a C.sub.1-2 alkyl, cyclopropyl or propargyl group, and any ring carbon atom being optionally substituted by a group R.sub.1 ; or a group ##STR3## which A.sub.1, A.sub.2 and A.sub.3 complete a 5-membered aromatic ring and A.sub.1 is oxygen or sulphur, one of A.sub.2 and A.sub.3 is CR.sub.2 and the other is nitrogen or CR.sub.3, or A.sub.2 is oxygen or sulphur, one of A.sub.1 and A.sub.3 is CR.sub.2 and the other is CR.sub.3 ; and R.sub.1, R.sub.2 and R.sub.
    Type: Grant
    Filed: August 2, 1990
    Date of Patent: November 28, 1995
    Assignee: Beecham Group p.l.c.
    Inventors: Harry J. Wadsworth, Paul A. Wyman, Steven Dabbs, Sarah M. Jenkins
  • 1,2,5,6-tetrahydropyridine oxime derivatives
    Patent number: 5356914
    Abstract: Compounds of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein R.sub.1 represents a 1,2,5,6-tetrahydropyridin-3-yl group N-substituted by R.sub.10 wherein R.sub.10 represents OH; a group hydrolysable in vivo to OH or hydrogen; C.sub.1-8 alkoxy; C.sub.2-8 alkenyloxy; C.sub.2-8 alkynyloxy; C.sub.3-8 cycloalkyloxy; or COR.sub.13 wherein R.sub.13 represents hydrogen, C.sub.1-8 alkyl, phenyl or phenyl C.sub.1-4 alkyl; in which any phenyl moiety is optionally substituted by up to 3 substituents independently selected from C.sub.1-6 alkoxy, C.sub.1-6 alkyl, halo, C.sub.1-6 alkoxycarbonyl, cyano, C.sub.1-6 alkylthio or C.sub.1-6 alkylsulphonyl; enhance acetylcholine function via an action at muscarinic receptors within the central nervous system and are therefore of potential use in the treatment and/or prophylaxis of dementia in mammals.
    Type: Grant
    Filed: April 5, 1993
    Date of Patent: October 18, 1994
    Assignee: Beecham Group p.l.c.
    Inventors: Steven M. Bromidge, Barry S. Orlek, Steven Dabbs
  • Pleuromutilin derivatives as antimicrobials
    Patent number: RE39128
    Abstract: The present invention relates to pleuromutilin derivatives, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medical therapy, particularly antibacterial therapy.
    Type: Grant
    Filed: October 27, 1998
    Date of Patent: June 13, 2006
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Valerie Joan Berry, Steven Dabbs, Colin Henry Frydrych, Eric Hunt, Francis Dominic Sanderson, Gary Woodnutt
  • Azabicylo oxime compounds
    Patent number: RE35593
    Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein R.sup.1 represents ##STR2## in which each of p and q independently represents an integer of 2 to 4, r represents an integer of 2 to 4, s represents 1 or 2 and t represents 0 or 1;R.sub.2 is a group OR.sub.4, where R.sub.4 is C.sub.1-4 alkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, a group OCOR.sub.5 where R.sub.5 is hydrogen or R.sub.4, or a group NHR.sub.6 or NR.sub.7 R.sub.8 where R.sub.6, R.sub.7 and R.sub.8 are independently C.sub.1-2 alkyl; andR.sub.3 is chloro, fluoro, bromo, cyclopropyl, C.sub.1-3 alkyl substituted by one, two or three halogen atoms, or R.sub.3 is a group (CH.sub.2).sub.n R.sub.9 where R.sub.9 is --CN, --OH, --OCH.sub.3, --SH, --SCH.sub.3, --C.tbd.CH or --CH.dbd.CH.sub.2 and n is O or 1, with the proviso that when n is 0, R.sub.9 is not --OH or --SH.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: August 19, 1997
    Assignee: Beecham Group p.l.c.
    Inventors: Barry S. Orlek, Steven M. Bromidge, Steven Dabbs
  • Pleuromutilin derivatives as antimicrobials
    Patent number: RE43390
    Abstract: The present invention relates to pleuromutilin derivatives, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medical therapy, particularly antibacterial therapy.
    Type: Grant
    Filed: October 27, 1998
    Date of Patent: May 15, 2012
    Assignees: GlaxoSmithKline LLC, SmithKline Beecham Limited
    Inventors: Valerie Joan Berry, Steven Dabbs, Colin Henry Frydrych, Eric Hunt, Francis Dominic Sanderson, Gary Woodnutt