Abstract: A power train arrangement having a prime mover and a transmission coupled to the prime mover for driving a cooling system with the prime mover through the transmission. The transmission is positioned intermediate to the prime mover and the cooling system in a manner to optimize the mechanical and functional operation of the work machine.

Abstract: A non-deforming deflectable multi-lumen catheter with an outer jacket having a deflectable distal end portion, an eccentric pull wire lumen, coil and shim embedded therein. The deflectable distal portion optionally having one or more transaxial notches in the external surface of the outer jacket. A functional device is disposed within the lumen of an inner tube substantially coaxial with the outer jacket of the catheter. The distal tip of the functional device egressible from the distal tip of the catheter, and upon deflection, automatically aligns with the distal tip of the catheter and functional device.

Abstract: The entire right, title and interest in and to this application and all subject matter disclosed and/or claimed therein, including any and all divisions, continuations, reissues, etc., thereof are, effective as of the date of execution of this application, assigned, transferred, sold and set over by the applicant(s) named herein to Deere & Company, a Delaware corporation having offices at Moline, Ill. 61265, U.S.A., together with all rights to file, and to claim priorities in connection with, corresponding patent applications in any and all foreign countries in the name of Deere & Company or otherwise.

Abstract: A vehicle brake system includes a primary hydraulic pump, a secondary variable delivery pump, left and right service brakes and left and right secondary brakes. A service brake valve is connected between the primary pump and the service brakes, and operates the service brakes in response to brake pedal operation. Left and right service brake switches generate signals representing operational status of the service brakes. An electrohydraulic secondary brake valve operates the secondary brakes in response to an electronic control signal. Brake pressure sensors generate brake pressure signals representing the service brake pressure and the secondary brake pressure. An electronic control unit is coupled to the service brake switches, to the pressure sensors and to the secondary brake valve. The control unit generates the control signal as a function of the status of the service brakes and of the brake pressure signals.

Abstract: Ablation devices and associated methods are provided for use in palliative treatment of a bone tumor on or in a compact bone region. The bone treatment devices include an elongate probe having a distal end. A proximal end of the probe supports placement in a location at or adjacent to the bone tumor. Electrodes are carried within the probe for deployment from the distal end into the bone tumor. The electrodes may be shapable to create, upon deployment, an array of electrodes that defines a geometric area within the bone tumor. Application of energy, for example energy from a radio frequency (RF) source, to the area of the bone tumor via the electrodes destroys at least a portion of the nerve receptors located in or adjacent to the tumor and produces a reduction in pain associated with the bone tumor.

Abstract: A tissue surface treatment apparatus includes a housing having a proximal end, a distal including a tissue contacting surface and an interior defined by the housing. A handpiece is coupled to the housing. The tissue contact surface has a plurality of apertures. An energy delivery device including at least one electrode is positionable in the housing interior. The at least one electrode includes a tissue penetrating distal end in substantial alignment with an aperture of the plurality of aperture. The at least one electrode is configured to be advanced from the housing interior through the aperture and into a target tissue site to define an ablation volume at least partly bounded by a tissue surface. An advancement device is coupled to the energy delivery device. The advancement device is at least partly positionable within at least one of the housing or the handpiece.

Abstract: The present invention relates to polynucleotides comprising genes that regulate cell proliferation. The present invention also relates to a method for diagnosing or monitoring the treatment of a disease characterized by the altered expression of genes that regulate cell proliferation in a sample.

Abstract: An integral yoke/slinger assembly replaces a conventional two-piece design. The integral yoke/slinger arrangement provides a new and improved shaft seal particularly adapted for use in yoke and flange arrangement exposed to a heavy concentration of air entrained foreign material, whereby a more efficient and economical method for manufacturing and assembling a yoke, slinger and seal arrangement for a drive axle system is provided.

Abstract: A viewing and treatment apparatus for performing minimally invasive surgery through an opening in a patient's chest, the apparatus includes a visualization scope with an elongated portion and a distal end, and a working device such as a tissue ablation energy delivery device. The working device is encompassed within a working channel that communicates with the distal end of the scope. In one embodiment, a bronchoscope is used whose catheter shafting includes an introducer sleeve at the distal section of the scope for providing stability during introduction to a patient's chest while stabilizing the treatment and visualization distal ends of the scope at a treatment site. This embodiment can include a needle piercing assembly that cooperatively works with the work device such as for drug delivery.

Abstract: A viewing and treatment apparatus for performing minimally invasive surgery through an opening in a patient's chest, the apparatus includes a visualization scope with an elongated portion and a distal end, and a working device such as a tissue ablation energy delivery device. The working device is encompassed within a working channel that communicates with the distal end of the scope. In one embodiment, a bronchoscope is used whose catheter shafting includes an introducer sleeve at the distal section of the scope for providing stability during introduction to a patient's chest while stabilizing the treatment and visualization distal ends of the scope at a treatment site. This embodiment can include a needle piercing assembly that cooperatively works with the working device such as for drug delivery.

Abstract: A viewing and treatment apparatus for performing minimally invasive surgery through an opening in a patient's chest, the apparatus includes a visualization scope with an elongated portion and a distal end, and a working device such as a tissue ablation energy delivery device. The working device is encompassed within a working channel that communicates with the distal end of the scope. In one embodiment, a bronchoscope is used whose catheter shafting includes an introducer sleeve at the distal section of the scope for providing stability during introduction to a patient's chest while stabilizing the treatment and visualization distal ends of the scope at a treatment site. This embodiment can include a needle piercing assembly that cooperatively works with the work device such as for drug delivery.

Abstract: A device for use in laser surgical procedures for moving axially an optical fiber element that is connected at its proximal end to a source of laser energy. The distal end of the fiber elements with a cooperating piercing tip member has a tapered configuration so that it is capable of penetrating soft tissue of membrane such as the myocardium or epicardium of a human heart during the revascularization procedure. Various combinations of bundled optical fiber elements are disclosed which provide different tapered distal end designs that can be used in various surgical procedures.

Abstract: A differential steer and final drive configuration for machines such as small tractors for agricultural and construction purposes and the like, which differential steer and final drive configuration allows passage of a power take-off (PTO) shaft beneath the differential steer mechanism and between the drive axles of the final drive mechanisms such that a PTO output member connected to the PTO shaft can be located on or in the vicinity of the machine front to rear centerline and the drive wheel axis.

Abstract: An apparatus, and method for endometrial ablation by heating an inflation medium within a distensible bladder positioned within a uterus of a patient. The apparatus comprises an elongate tubular member, a handle, a distensible bladder and a heating element disposed within said distensible bladder. The system includes a controller configured for providing and regulating electric current to the heating element. The controller also includes a pressure sensor for regulating the pressure in the distensible bladder. Pressure and temperature displays and other operator controls are located on the controller unit. The method for performing endothelial ablation comprises inserting the distensible bladder and a portion of the tubular member into a uterus of a patient. The inflation medium within the distensible bladder is heated by providing electric current to the resistive wire of the heating element.

Abstract: An instrument for cutting, ablating and coagulating tissue has a rod of ferromagnetic material fusion welded to the base of a conical tip of copper with the rod adjacent the base of the conic being of lesser diameter than the base to provide a region to accept a potted coil of wire about the rod whereby when the coil is connected to a constant current high frequency source the rod and tip are heated to a temperature approaching the Curie temperature of the ferromagnetic rod. As Curie temperature is approached the rod becomes essentially non-magnetic heating decreases to produce a temperature below Curie temperature and the cycle repeats. As a result of the excellent heat exchange interfaces produced by fusion welding the energy delivered to the tissue or other load which may be non-biological is closely controlled by temperature which is self regulated. A ferromagnetic sleeve is placed about the coil to concentrate magnetic flux in the rod.

Abstract: A Curie point heater primarily for use in a soldering iron and initially designed to operate with currents in the megahertz range is restructured to operate in the kilohertz range. Further in one embodiment of the heater, the coil exciting the heater is mounted in the handle of the iron.