Abstract: An ablation device is described comprising an introducer and an electrode array. The electrode array couples to a distal end of the introducer. The electrode array includes a center member having a distal end configured to penetrate tissue and a plurality of electrodes. Proximal and distal ends of each electrode are relatively fixed. The electrodes are dynamically configurable from a retracted state to a deployed state in which the electrodes form a relatively spherical shape in a tissue volume.

Abstract: Methods for performing coagulation necrosis of biological tissue are provided. The methods include configuring electrode arrays to provide balanced energy density in target tissue volumes using two or more pair of electrodes. The electrode array configuration includes at least one of irregular spacing between one or more pairs of electrodes and one or more electrode diameters. The methods further include deploying each electrode of an array at a selected depth in the target tissue volume in accordance with the configuration. Energy is then delivered to the target tissue volume using power sources coupled to the electrodes. The methods control power delivery in response to at least one of elapsed time of delivery, temperatures of the target tissue volume, and impedance levels in the target tissue volume to provide balanced or uniform energy throughout the target tissue volume. The methods generate planes of coagulated tissue.

Abstract: The invention is directed to methods for measuring the performance of protein microarrays. The invention provides a multiplex micro-ELISA system.

Abstract: The invention provides methods for simultaneous detection of multiple secondary modifications, such as “post-translational modifications”, of target molecules, e.g., polypeptides, utilizing an “array” format.

Abstract: A vacuum packaging machine includes a vacuum chamber and a sealing mechanism within the chamber. A product-filled package can be supported within the chamber with its open end disposed between sealing bars of a sealing mechanism. At least one of the sealing bars is continuously heated including as the package is placed within the chamber, as a vacuum is drawn in the chamber, as the sealing bars are closed around the open end of the package and as the package is removed after sealing is complete.

Abstract: Method of producing controls for use in gene expression analysis systems such as macroarrays, real-time PCR, northern blots, SAGE and microarrays. The controls are generated either from near-random sequence of DNA, or from inter- or intragenic regions of a genome. Ten specific control sequences are also disclosed. Also presented are methods of using these controls, including as negative controls, positive controls, and as calibrators of a gene expression analysis system.

Abstract: A vehicle brake system includes a primary hydraulic pump, a secondary variable delivery pump, left and right service brakes and left and right secondary brakes. A service brake valve is connected between the primary pump and the service brakes, and operates the service brakes in response to brake pedal operation. Left and right service brake switches generate signals representing operational status of the service brakes. An electrohydraulic secondary brake valve operates the secondary brakes in response to an electronic control signal. Brake pressure sensors generate brake pressure signals representing the service brake pressure and the secondary brake pressure. An electronic control unit is coupled to the service brake switches, to the pressure sensors and to the secondary brake valve. The control unit generates the control signal as a function of the status of the service brakes and of the brake pressure signals.

Abstract: An electrically operated equipment with a sealed enclosure containing circuitry with an exterior visual indicator to show a state of operation of the equipment. The visual indicator is illuminated by a magnetic flux sensor also exterior to the equipment, the sensor inducing an electrical current from a sensed magnetic flux passing through a permeable wall of the enclosure. The magnetic flux is provided by a magnetic field generator within the enclosure. The generator is connected to the equipment to generate the field when the circuitry is operating correctly whereby the indicator shows a correct state of operation. The invention avoids the use of sealed orifices in the enclosure for conductors to pass to exterior LEDs or LEDs sealed within the enclosure and possible resultant leakage. The invention is useful for optical network units. The invention also includes a visual indicating device of multi-layer configuration and a method of visually indicating the operational state of circuitry.

Abstract: A vehicle suspension system includes a fluid pump, a pair of suspension cylinders and a hydraulic control circuit for controlling pressurization of the suspension cylinders. Each suspension cylinder has a head end and a rod end. The control circuit includes a proportional rod pressure control valve with a first pilot which is exposed to a pressure which is communicated to the head end of the suspension cylinder, and a second pilot which is exposed to pressure which is communicated to the rod end of the suspension cylinder. The rod pressure control valve controls pressure in the rod end of the suspension cylinder as a function of and proportional to the pressure in the head end of the suspension cylinder. A suspension damping valve controls communication between a chamber of the cylinder and an accumulator.

Abstract: The entire right, title and interest in and to this application and all subject matter disclosed and/or claimed therein, including any and all divisions, continuations, reissues, etc., thereof are, effective as of the date of execution of this application, assigned, transferred, sold and set over by the applicant(s) named herein to Deere & Company, a Delaware corporation having offices at Moline, Ill. 61265, U.S.A., together with all rights to file, and to claim priorities in connection with, corresponding patent applications in any and all foreign countries in the name of Deere & Company or otherwise.

Abstract: A vehicle brake system includes a primary hydraulic pump, a secondary variable delivery pump, left and right service brakes and left and right secondary brakes. A service brake valve is connected between the primary pump and the service brakes, and operates the service brakes in response to brake pedal operation. Left and right service brake switches generate signals representing operational status of the service brakes. An electrohydraulic secondary brake valve operates the secondary brakes in response to an electronic control signal. Brake pressure sensors generate brake pressure signals representing the service brake pressure and the secondary brake pressure. An electronic control unit is coupled to the service brake switches, to the pressure sensors and to the secondary brake valve. The control unit generates the control signal as a function of the status of the service brakes and of the brake pressure signals.

Abstract: The present invention relates to polynucleotides comprising genes that regulate cell proliferation. The present invention also relates to a method for diagnosing or monitoring the treatment of a disease characterized by the altered expression of genes that regulate cell proliferation in a sample.

Abstract: An integral yoke/slinger assembly replaces a conventional two-piece design. The integral yoke/slinger arrangement provides a new and improved shaft seal particularly adapted for use in yoke and flange arrangement exposed to a heavy concentration of air entrained foreign material, whereby a more efficient and economical method for manufacturing and assembling a yoke, slinger and seal arrangement for a drive axle system is provided.