Abstract: This disclosure relates to systems and methods for selecting an application to handle a message. In one example, a method includes receiving a first message from a first member of an online social networking service using a first computing device, the first message addressed to a second member of the online social networking service, determining which application the first member used to generate the first message, receiving a second message from the second member, the second message being a reply message to the first message, and transmitting the second message to the first computing device that includes an instruction that the determined application is to handle the second message.