Abstract: A wearable device for suppressing appetite or hunger in a patient includes a microprocessor, electrical stimulator and at least one electrode configured to deliver electrical stimulation to the epidermis, through a range of 0.1 mm to 10 mm or a range of 0.1 mm to 20 mm of the dermis, of a T2 frontal thoracic dermatome to a T12 frontal thoracic dermatome or meridian of the patient and/or front or back, C5-T1 dermatome across the hand and/or arm, and/or the upper chest regions. The device includes a pad, in which the electrode is disposed, for secure placement of the device on a skin surface of a patient. The device is adapted to provide electrical stimulation as per stimulation protocols and to communicate wirelessly with a companion control device configured to monitor and record appetite patterns of the patient. The control device is also configured to monitor, record, and modify stimulation parameters of the stimulation protocols.

Abstract: A physiological parameter associated with tissue of a host may be monitored in the tissue to confirm subcutaneous delivery of medication to the host. More particularly, such may involve delivering medication subcutaneously to the host with a medical device which includes a sensor used to measure the physiological parameter, particularly within a predetermined time period after delivery of the medication. Such may also or otherwise involve forming a depot in the tissue with the medication, and using the sensor to measure the physiological parameter while the sensor is at least partially within the depot.

Abstract: An infusion device comprising a fluid reservoir for containing a therapeutic fluid; and a transcutaneous access tool fluidly coupled to the fluid reservoir for delivering the therapeutic fluid subcutaneously and for introducing a monitoring test strip subcutaneously, and methods of use thereof.

Abstract: A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir; and a drive mechanism for driving fluid from the reservoir, the drive mechanism comprising a plunger received in the reservoir; a leadscrew extending from the plunger; a nut threadably engaged with the leadscrew; a drive wheel; and a clutch mechanism coupled to the drive wheel, wherein the clutch mechanism is configured to allow the nut to pass through when disengaged and is configured to grip the nut when engaged such that the drive wheel rotates the nut to advance the drive rod and the plunger into the reservoir.

Abstract: A chassis for a fluid delivery device provides mechanical and/or electrical connections between components of the fluid delivery device. The chassis includes a framework of structural members that mechanically interface components, such as a batteries, electrical contacts, fluid reservoirs, tubing, drive wheels, pivoting actuator components, sensors, control circuitry, alarms or indicators, sliding assemblies, springs, cams and latching members. The chassis may also include one or more electrically conductive paths along selected portions of the framework to provide electrical connections between the components.

Abstract: A fluid delivery device may include a fluid driving mechanism for driving fluid out of a reservoir and an actuating mechanism for actuating the driving mechanism. The fluid delivery device may also include one or more sensors for monitoring operation of the fluid delivery device. The fluid delivery device may also include a chassis providing mechanical and/or electrical connections between components of the fluid delivery device.

Abstract: A device for delivering fluid to a patient, including a reservoir, a dispenser for causing fluid to flow from the reservoir, a local processor connected to the dispenser and programmed to cause a flow of fluid from the reservoir based solely on flow instructions from a separate, remote control device, a power supply connected to the local processor, a wireless receiver connected to the local processor for receiving the flow instructions from a separate, remote control device and delivering the flow instructions to the local processor, and a housing containing the reservoir, the dispenser, the local processor, the power supply and the wireless receiver. At least two of the reservoir, the dispenser and the power supply are vertically stacked within the housing and at least one of the dispenser and the power supply has a horizontal cross-sectional area that is greater than fifty percent of a cross-sectional area of the housing.