Abstract: The invention provides a method and apparatus of removing contaminants such as salts, hydrocarbon, chemicals, minerals, and metals from materials such as sand, soil, gravel, drill cuttings, and other solids, and reclaiming contaminants and materials for reuse. The invention is scalable in size and capability, economic to construct and operate and reliable in operation and performance. The invention slurries contaminated material with a solution. Transports the slurried material throughout a hydraulic chamber, where the contaminants become more associated with the solution than the material. The invention then separates the processed material and contaminated solution into unique reclaimed components.

Abstract: The disclosure for the first time provides an understanding of the mechanism of prion protein infection: prion proteins contain a cationic protein transduction domain (PTD) that interacts with the cell surface such that it induces macropinocytosis and enters the cytoplasm.

Abstract: Due to the barrier imposed by the cell membrane, delivery of macromolecules in excess of 500 Daltons directly into cells remains problematic. However, proteins, which have been evolutionarily selected to perform specific functions, are therefore an attractive therapeutic agent to treat a variety of human diseases. In practice, the direct intracellular delivery of these proteins has, until recently, been difficult to achieve due primarily to the bioavailability barrier of the plasma membrane, which effectively prevents the uptake of the majority of peptides and proteins by limiting their passive entry. However, recent work using small cationic peptides, termed protein transduction domains (PTDs), derived from polynucleotide binding proteins, such as HIV TAT protein or the Drosophila transcription factor Antp. or synthetic poly-Arginine, have now been shown to deliver a myriad of molecules, including synthetic small molecules, peptides and proteins, into animal models in vivo.

Abstract: In one embodiment, a vehicular collision avoidance method is provided that includes monitoring a control of a vehicle and activating a first alarm if the control is not adjusted in a sufficient amount of time. The monitored control is normally and regularly adjusted by the vehicle's operator such that the time between adjustments is sufficiently smaller than the time normally needed to avoid a collision after it is detected that the control is no longer being controlled. The first alarm is activated if it is determined that the control is not adjusted in a sufficiently small amount of time from its preceding adjustment. Thus, the vehicle's operator or other vehicle member can react and take measures to ensure that the vehicle is under suitable control upon activation of the alarm and thereby avoid a possible collision.