Patents by Inventor Steven E. Lunetta

Steven E. Lunetta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoassay reagents and method for determining cyclosporine
    Patent number: 5750413
    Abstract: Cyclosporine derivatives useful as detectable tracer compounds for the immunoassay determination of cyclosporine are disclosed. The cyclosporine derivatives comprise a detectable moiety coupled to the amino acid at the first position (MeBmt) in cyclosporine, the second position (Abu) in cyclosporine, the third position (Sar) in cyclosporine, the eighth position (D-Ala) in cyclosporine, or the tenth position (MeLeu) in cyclosporine. A preferred cyclosporine derivative comprises a fluorescent moiety coupled to the hydroxyl group of the amino acid at the first position in cyclosporine, and is especially useful for the fluorescent polarization immunoassay determination of cyclosporine. A fluorescent polarization immunoassay method and test kit are also disclosed.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: May 12, 1998
    Assignee: Abbott Laboratories
    Inventors: Marjorie A. Morrison, Steven E. Lunetta, Victoria P. Meucci, Mariola B. Zajac, Elizabeth A. Simpson
  • Immunoassay reagents and method for determining cyclosporine
    Patent number: 5489668
    Abstract: Cyclosporine derivatives useful as detectable tracer compounds for the immunoassay determination of cyclosporine are disclosed. The cyclosporine derivatives comprise a detectable moiety coupled to the amino acid at the first position (MeBmt) in cyclosporine, the second position (Abu) in cyclosporine, the third position (Sar) in cyclosporine, the eighth position (D-Ala) in cyclosporine, or the tenth position (MeLeu) in cyclosporine. A preferred cyclosporine derivative comprises a fluorescent moiety coupled to the hydroxyl group of the amino acid at the first position in cyclosporine, and is especially useful for the fluorescent polarization immunoassay deterimination of cyclosporine. A fluorescent polarization immunoassay method and test kit are also disclosed.
    Type: Grant
    Filed: November 4, 1993
    Date of Patent: February 6, 1996
    Assignee: Abbott Laboratories
    Inventors: Marjorie A. Morrison, Steven E. Lunetta, Victoria P. Meucci, Mariola B. Zajac, Elizabeth A. Simpson
  • Method for preparing a dicarboxylic acid half-acid ester of FK506
    Patent number: 5164495
    Abstract: Disclosed is an improved method for the synthesis of FK506-hemisuccinate for utilization in the preparation of components for as assay for FK506.
    Type: Grant
    Filed: September 18, 1991
    Date of Patent: November 17, 1992
    Assignee: Abbott Laboratories
    Inventor: Steven E. Lunetta