Abstract: The present invention relates to a methods and compositions for the treatment of and management of symptoms for thyroid eye disease. The methods include administering to a patient having thyroid eye disease an agent that interferes with hyaluronan synthesis in an amount that is effective to inhibit hyaluronan synthesis in a retro-ocular space. The pharmaceutical compositions that includes a carrier suitable for ophthalmic delivery and an agent that interferes with hyaluronan synthesis. Combination therapies are also disclosed.

Abstract: The present invention relates to a methods and compositions for the treatment of and management of symptoms for thyroid eye disease. The methods include administering to a patient having thyroid eye disease an agent that interferes with hyaluronan synthesis in an amount that is effective to inhibit hyaluronan synthesis in a retro-ocular space. The pharmaceutical compositions hat includes a carrier suitable for ophthalmic delivery and an agent that interferes with hyaluronan synthesis. Combination therapies are also disclosed.

Abstract: The present invention relates to a methods and compositions for the treatment of and management of symptoms for thyroid eye disease. The methods include administering to a patient having thyroid eye disease an agent that interferes with hyaluronan synthesis in an amount that is effective to inhibit hyaluronan synthesis in a retro-ocular space. The pharmaceutical compositions hat includes a carrier suitable for ophthalmic delivery and an agent that interferes with hyaluronan synthesis. Combination therapies are also disclosed.

Abstract: A calibration device for use with a fundus camera is described, including a mock retina having a curvature from a front portion to a back portion. The calibration device further includes a color model having a range of colors comparable to a range of colors of the fundus of an eye. The calibration device further can include a lens for magnification and is configured to facilitate generation of an image to evaluate and adjust an ophthalmic imaging system for features such as color, magnification, and resolution.

Abstract: The present invention relates to a methods and compositions for the treatment of and management of symptoms for thyroid eye disease. The methods include administering to a patient having thyroid eye disease an agent that interferes with hyaluronan synthesis in an amount that is effective to inhibit hyaluronan synthesis in a retro-ocular space. The pharmaceutical compositions hat includes a carrier suitable for ophthalmic delivery and an agent that interferes with hyaluronan synthesis. Combination therapies are also disclosed.

Abstract: Embodiments of a compact camera for imaging the ocular fundus are described. In some embodiments, the camera is a light, handheld camera that acquires a plurality of images of the fundus. The camera can be configured to acquire images manually or automatically. A movable imaging lens or movable image detector provides the images in a series to obtain an image with optimal focus. The camera can acquire a series of images and allow selection of an optimal image either manually, or automatically. In some embodiments, the camera is part of an imaging system that includes a base station. The base station exchanges data with the camera and can receive image data generated by the image detector of the camera. The base can further include networking capability, such that image data can be distributed over a network or to other communication or computing devices.

Abstract: Embodiments of a compact camera for imaging the ocular fundus are described. In some embodiments, the camera is a light, handheld camera that acquires a plurality of images of the fundus. The camera can be configured to acquire images manually or automatically. A movable imaging lens or movable image detector provides the images in a series to obtain an image with optimal focus. The camera can acquire a series of images and allow selection of an optimal image either manually, or automatically. In some embodiments, the camera is part of an imaging system that includes a base station. The base station exchanges data with the camera and can receive image data generated by the image detector of the camera. The base can further include networking capability, such that image data can be distributed over a network or to other communication or computing devices.

Abstract: There is disclosed herein an applanation tonometer and more particularly a new form of disposable tip cover therefor. The tonometer includes a fiber optic array cylinder. A disposable tip cover comprising a translucent and light diffusing film is used on the exterior tip of the cylinder. The tip cover can be retained on the cylinder by sandwiching the cover between a pair of inner and outer flexible rings, the inner ring being attachable to the tip of the fiber optic array cylinder.