Abstract: In an aspect, a stress mitigation system is provided for mitigating stresses in a wearer of a headgear configured to apply a load on the wearer that is offset from a center of gravity of the wearer's head to apply a first torque in a first direction on the wearer's head. The system includes a track, a shuttle, and a flexible elongate connector. The track is mounted to either the headgear or a bodywear member and extends generally laterally. The shuttle is movable along the track. The connector is configured to connect between the shuttle and the other of the headgear and the bodywear member. The connector applies a second torque on the headgear in a second direction that is generally opposite to the first direction. When the wearer's head pivots, the shuttle is movable laterally along the track to maintain the connector in a substantially vertical orientation.

Abstract: Fitts's law is a predictive model of human movement primarily used in human-computer interaction, ergonomics, and medical assessments. A cervical orientated assessment allows assessments of aspects of users such as injuries, concussions, impacts of equipment as well as ergonomic assessments etc. Accordingly, a three-dimensional visual target acquisition system (3D-VTAS) provides measurements based upon a cervical oriented Fitts' Law paradigm in a manner which provides for ease of use, high between-day reliability and validity based upon healthy subject's performance. The 3D-VTAS also provides increased data allowing determination/verification if there are movement trajectory or target size confounds between the measurements of a subject's performance and hence assessments of both healthy and non-healthy individuals as well as assessments of ergonomic factors etc.

Abstract: Fitts's law is a predictive model of human movement primarily used in human-computer interaction, ergonomics, and medical assessments. A cervical orientated assessment allows assessments of aspects of users such as injuries, concussions, impacts of equipment as well as ergonomic assessments etc. Accordingly, a three-dimensional visual target acquisition system (3D-VTAS) provides measurements based upon a cervical oriented Fitts' Law paradigm in a manner which provides for ease of use, high between-day reliability and validity based upon healthy subject's performance. The 3D-VTAS also provides increased data allowing determination/verification if there are movement trajectory or target size confounds between the measurements of a subject's performance and hence assessments of both healthy and non-healthy individuals as well as assessments of ergonomic factors etc.

Abstract: In an aspect, a stress mitigation system is provided for mitigating stresses in a wearer of a headgear configured to apply a load on the wearer that is offset from a center of gravity of the wearer's head to apply a first torque in a first direction on the wearer's head. The system includes a track, a shuttle, and a flexible elongate connector. The track is mounted to either the headgear or a bodywear member and extends generally laterally. The shuttle is movable along the track. The connector is configured to connect between the shuttle and the other of the headgear and the bodywear member. The connector applies a second torque on the headgear in a second direction that is generally opposite to the first direction. When the wearer's head pivots, the shuttle is movable laterally along the track to maintain the connector in a substantially vertical orientation.

Abstract: Systems and techniques are disclosed that allow a user to enter a query in a query input region of a graphical user interface and respond to the query by automatically directing it to an appropriate database, saving a user from having to choose among the myriad databases within the system. The system provides shareable folders for not only selected documents or excerpts from documents, but also for annotations and markups associated with documents. The system also enables a user to set permissions as to whether to allow documents, as well annotations and markups, private or publicly available to other users. Further, the system allows a user to specify an action that is to occur once a particular event occurs affecting a document, annotation or markup.

Abstract: A mass calibration apparatus for a mass spectrometer includes a capillary, an analyte ion source coupled to the capillary at a first point, a reference mass ion source coupled to the capillary at a second point, downstream from the first point and a mass analyzer coupled to the capillary at a third point downstream from the first and second points. The reference mass ion source may be coupled to the capillary via a tee junction. The reference mass ion source includes a chamber, an ionization device situated within the chamber and one or more reference mass sources that are situated internally within the chamber or are situated external to and coupled to the chamber.

Abstract: Apparatus and method according to the disclosure relate to minimizing gaps between a substantially planar cardiac-sensing electrode and a shroud member utilizing a so-called interference-fit. For example, a relatively recessed area or aperture formed in an exemplary resin-based shroud member has slightly reduced dimensions relative to the electrode and requires compression forces during assembly (e.g., manually or in an automated process including a press, a tool or other means). The interference-fit promotes a very tight fit (or seal) between the metallic electrode and the resin-based shroud member and, importantly, minimizes gaps. Additionally, discrete interference structures promote fluid tight seals between the electrode and a recess or aperture adapted to receive the electrode.

Abstract: An ion sampling apparatus for use in a mass spectrometry system. The ion sampling apparatus includes a target support for receiving a sample, an irradiation source for emitting energetic radiation or particles toward the target support, and a conduit having a curved end and a longitudinal axis, the curved end having an inlet with a central axis, the conduit being adjacent to the target support. The longitudinal axis of the conduit and the central axis of the inlet intersect to define an angle that is between about 20 degrees and about 210 degrees.

Abstract: A method and apparatus for calibrating a mass spectrometry system in which lock mass ions are introduced into the transport region of a mass spectrometer intermittently in a pulsed manner and analyte ions and/or lock mass ions are then detected at the mass analyzer. In one embodiment, analyte ions are also introduced into the transport region of the mass spectrometer from the analyte ion source intermittently in a pulsed manner.

Abstract: A method and apparatus for calibrating a mass spectrometry system in which lock mass ions are introduced into the transport region of a mass spectrometer intermittently in a pulsed manner and analyte ions and/or lock mass ions are then detected at the mass analyzer. In one embodiment, analyte ions are also introduced into the transport region of the mass spectrometer from the analyte ion source intermittently in a pulsed manner.

Abstract: A mass calibration apparatus for a mass spectrometer includes a capillary, an analyte ion source coupled to the capillary at a first point, a reference mass ion source coupled to the capillary at a second point, downstream from the first point and a mass analyzer coupled to the capillary at a third point downstream from the first and second points. The reference mass ion source may be coupled to the capillary via a tee junction. The reference mass ion source includes a chamber, an ionization device situated within the chamber and one or more reference mass sources that are situated internally within the chamber or are situated external to and coupled to the chamber.

Abstract: A technique for generating a physical representation of networked components makes use of data stored within the individual components, which may be polled by a monitoring station. The data includes identification of the respective component, and data representative of a physical disposition of the component in the system. Based upon the data, the monitoring station builds a physical representation of the system, including approximately accurate physical representations of the individual components with identifying labels, facilitating monitoring and servicing of the components.

Abstract: The present invention provides an apparatus and method for use with a mass spectrometer. The multimode ionization source of the present invention provides one or more atmospheric pressure ionization sources (e.g., electrospray, atmospheric pressure chemical ionization and/or atmospheric pressure photoionization) for ionizing molecules. A method of producing ions using the multimode ionization source is also disclosed. The apparatus and method provide the advantages of the combined ion sources without the inherent disadvantages of the individual sources. In an embodiment, the multimode ionization source includes an infrared emitter enclosed in an inner chamber for drying a charged aerosol. ESI/APCI multimode sources may include a corona needle shield and/or an auxiliary electrode.

Abstract: The present invention provides an apparatus and method for use with a mass spectrometer. The multimode ionization source of the present invention provides one or more atmospheric pressure ionization sources (e.g., electrospray, atmospheric pressure chemical ionization and/or atmospheric pressure photoionization) for ionizing natural product and organic molecules. A method of producing ions using the multimode ionization source is also disclosed. The apparatus and method provide the advantages of the combined ion sources without the inherent disadvantages of the individual sources. In an embodiment, the multimode ionization source includes an infrared emitter enclosed in an inner chamber for drying a charged aerosol. ESI/APCI multimode sources may include a corona needle shield and/or an auxiliary electrode.

Abstract: The present invention relates to an apparatus for producing ions from an electrospray assembly. The apparatus comprises an ionization chamber, an electrospray assembly, an isolating electrode, an isolated ionization region within the ionization chamber and optionally, a vacuum interface at a vacuum interface voltage and a vacuum chamber. Sample is introduced into the ionization chamber from an electrospray assembly and transported to an electric field region that is isolated from the electric field created by the electrospray assembly.

Abstract: For generation and delivery of ions from an ionization chamber through an ion entrance orifice to a mass analyzer operating at high vacuum, high pass ion filtration is effected within the ionization chamber by application of electrical potentials to an electrode associated with the ion entrance orifice and to an electrode between the ionization region and the ion entrance orifice to create a retarding electric field upstream from the ion entrance orifice. The retarding electric field hinders the movement to the ion entrance orifice of ions having drift velocities below a lower limit, and as the retarding voltage gradient is made steeper, the lower limit increases.

Abstract: The present invention relates to an apparatus and method for use with a mass spectrometry system. The invention provides an ion source, infrared emitter and sensor with closed control feedback loop coupled to the infrared emitter. Methods of control and heating using the apparatus of the present invention are also disclosed.

Abstract: A mass spectrometer having a matrix-assisted laser desorption ionization (MALDI) source which operates at ambient pressure is disclosed.

Abstract: A polymer fluid flow component configured to sealingly couple with a second fluid flow component, the fluid flow component having a protruding portion and a receiving portion configured to receive the protruding portion. The fluid flow component can include a stop surface disposed on the protruding portion and a cooperating stop surface on the receiving portion to cooperate with the stop surface. The fluid flow component can further include an annular ring integrally formed with the valve, such that the annular ring is subjected to a compressive force when the receiving portion receives the protruding section sealingly coupling the valve and second component. The stop surface can engage the cooperating stop surface to inhibit overtightening of the valve.