Abstract: A method for integrating chemometric model development and chemometric model application to a process system, the method comprising: (1) receiving spectral data from a process system, the received spectral data corresponding to material being monitored by the process system; (2) receiving user input through at least one graphic user interface; (3) developing at least one chemometric model at least partially in response to the received user input; and (4) applying at least one chemometric model to the received spectral data to thereby predict a property of the material being monitored; and wherein the developing step and the applying step are performed by an integrated software program. Systems and software related to this method are also disclosed herein.