Patents by Inventor Steven G. Kultgen

Steven G. Kultgen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5- PHENYL-ISOXAZOLE-3-CARBOXAMIDE DERIVATIVES AS TRPV1 MODULATORS
    Publication number: 20110065764
    Abstract: The present invention relates to isoxazole-3-carboxamide derivative having the general Formula (I), or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of said isoxazole-3-carboxamide derivatives for the treatment of TRPV1 mediated disorders, such as acute and chronic pain disorders, acute and chronic neuropathic pain, acute and chronic inflammatory pain, respiratory diseases, and lower urinary tract disorders.
    Type: Application
    Filed: July 31, 2008
    Publication date: March 17, 2011
    Applicant: N.V. ORGANON AND PHARMACOPEIA, LLC
    Inventors: Andrew Laird Roughton, Koc-Kan Ho, Michael Ohlmeyer, Irina Neagu, Steven G. Kultgen, Nasrin Ansari, Yajing Rong, Paul David Ratcliffe, Ronald Palin
  • 2-(aminomethyl) arylamide analgesics
    Patent number: 7084154
    Abstract: A chemical genus of 2-(aminomethyl)arylamides, which are useful as analgesics, is disclosed.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: August 1, 2006
    Assignee: Pharmacopeia Drug Disclovery, Inc.
    Inventors: Koc-Kan Ho, John J. Baldwin, Adolph C. Bohnstedt, Steven G. Kultgen, Edward McDonald, Tao Guo, John Richard Morphy, Zoran Rankovic, Robert Horlick, Kenneth C. Appell
  • Pyrimidine derivatives as IL-8 receptor antagonists
    Patent number: 7037916
    Abstract: Compounds containing the pyrimidine nucleus and their use to treat diseases and conditions related to inappropriate Interleukin-8 receptor activity are disclosed. The compounds are of the formula I In these compounds, Q is preferably unsubstituted and substituted heterocyclyl; U is usually hydrogen or fluorine; and V is preferably hydrogen, halogen, alkyl, —O—alkyl or —S-alkyl.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: May 2, 2006
    Assignee: Pharmacopeia Drug Discovery, Inc.
    Inventors: Shawn David Erickson, John J. Baldwin, Roland Ellwood Dolle, III, James Inglese, Michael H. J. Ohlmeyer, Koc-Kan Ho, Adolph C Bohnstedt, Steven G. Kultgen, Paolo Giovanni Martino Conti, Dirk Leysen, Jaap van der Louw
  • Bisaryl derivatives having FSH modulatory activity
    Patent number: 6900213
    Abstract: The invention relates to bisaryl derivatives of the formula I, wherein (R,R) is selected from (H,H), O, (H,CH3), (H,OH) and (H,CN); Ar is substituted phenyl and A is a group of formula II, III, IV or V: An example is (3S,6S)-1-N-(7-phenylheptyl)-3-(4-(3,4,5-trimethoxyphenyl)benzyl)-4-N-methyl-6-methyl-2,5-dioxo-1,4-piperazine: The compounds of the invention have FSH receptor modulatory activity and can be used for the control of fertility, for contraception or for treatment of hormone-dependent disorders.
    Type: Grant
    Filed: July 21, 2003
    Date of Patent: May 31, 2005
    Assignee: Pharmacopeia Drug Discovery, Inc.
    Inventors: Tao Guo, Koc-Kan Ho, Edward McDonald, Roland Ellwood Dolle, Kurt W. Saionz, Steven G. Kultgen, Ruiyan Liu, Guizhen Dong, Peng Geng, Anton Egbert Peter Adang, Nicole Corine Renee Van Straten
  • 2-(aminomethyl) arylamide analgesics
    Publication number: 20040167119
    Abstract: A chemical genus of 2-(aminomethyl)arylamides, which are useful as analgesics, is disclosed.
    Type: Application
    Filed: February 11, 2003
    Publication date: August 26, 2004
    Applicant: PHARMACOPEIA, INC
    Inventors: Koc-Kan Ho, John J. Baldwin, Adolph C. Bohnstedt, Steven G. Kultgen, Edward McDonald, Tao Guo, John Richard Morphy, Zoran Rankovic, Robert Horlick, Kenneth C. Appell
  • Bisaryl derivatives having FSH modulatory activity
    Publication number: 20040152703
    Abstract: The invention relates to bisaryl derivatives of the formula I, 1
    Type: Application
    Filed: July 21, 2003
    Publication date: August 5, 2004
    Inventors: Tao Guo, Koc-Kan Ho, Edward McDonald, Roland Ellwood Dolle, Kurt W. Saionz, Steven G. Kultgen, Ruiyan Liu, Guizhen Dong, Peng Geng, Anton Egbert Peter Adang, Nicole Corine Renee Van Straten
  • Pyrimidine derivatives as IL-8 receptor antagonists
    Publication number: 20040087601
    Abstract: Compounds containing the pyrimidine nucleus and their use to treat diseases and conditions related to inappropriate Interleukin-8 receptor activity are disclosed.
    Type: Application
    Filed: January 10, 2003
    Publication date: May 6, 2004
    Inventors: Shawn David Erickson, John J. Baldwin, Roland Ellwood Dolle, James Inglese, Michael H.J. Ohlmeyer, Koc-Kan Ho, Adolph C. Bohnstedt, Steven G. Kultgen, Paolo Giovanni Martino Conti, Dirk Leysen, Jaap van der Louw