Abstract: An apparatus for making a sterile emulsion, comprising a fluid pathway, a pumping bore, a reciprocable (reciprocal) member, and a valve body. The pumping bore being in fluid communication with the fluid pathway and having a reciprocable member reciprocably disposed in the pumping bore. The reciprocable member having first portion disposed in fluid communication with the fluid pathway and a second portion isolated from the fluid pathway, said second portion having a sterilant passage adjacent thereto. The fluid pathway, reciprocable member first portion and reciprocable member second portion may be sterilized and one or more emulsion constituents may be directed into the fluid pathway defined by the piston apparatus after sterilization. The valve body defines a valve bore in communication with the fluid pathway and a valve plunger disposed therein. The valve body may also be configured to maintain emulsion sterility.