Patents by Inventor Steven G. Wright

Steven G. Wright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymer-based sustained release device
    Patent number: 7612176
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Grant
    Filed: July 16, 2007
    Date of Patent: November 3, 2009
    Assignee: Alkermes, Inc.
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Henry R. Costantino
  • POLYMER-BASED SUSTAINED RELEASE DEVICE
    Publication number: 20090247463
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Application
    Filed: June 12, 2009
    Publication date: October 1, 2009
    Applicants: Alkermes, Inc., Amylin Pharmaceuticals, Inc.
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Mark Fineman, Christine Smith, John Ong, David Lokensgard, Henry R. Costantino
  • Polymer-based sustained release device
    Patent number: 7563871
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Grant
    Filed: September 14, 2006
    Date of Patent: July 21, 2009
    Assignees: Alkermes, Inc., Amylin Pharmaceuticals, Inc.
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Mark Fineman, Christine Smith, John Ong, David Lokensgard, Henry R. Costantino
  • Apparatus and method for preparing microparticles using in-line solvent extraction
    Patent number: 7510730
    Abstract: Apparatus and method for preparing microparticles using in-line solvent extraction. An emulsion is formed by combining two phases in a static mixer. The emulsion is combined with an extraction liquid in a blending static mixer. The outflow of the blending static mixer is combined with additional extraction liquid. The additional extraction liquid and the outflow of the blending static mixer can be combined in a vessel, or through the use of a static mixer manifold that includes a plurality of static mixers.
    Type: Grant
    Filed: July 16, 2007
    Date of Patent: March 31, 2009
    Assignee: Alkermes, Inc.
    Inventors: Shawn L. Lyons, Steven G. Wright
  • Poly(lactide-Co-glycolide) based sustained release microcapsules comprising a polypeptide and a sugar
    Publication number: 20090035253
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Application
    Filed: April 15, 2005
    Publication date: February 5, 2009
    Applicants: AMYLIN PHARMACEUTICALS, INC., ALKEMES CONTROLLED THERAPEUTICS,
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Henry R. Costantino, Christine M. Smith, David Lokensgard, Mark Fineman, John Ong
  • Polymer-based sustained release device
    Patent number: 7456254
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Grant
    Filed: April 13, 2005
    Date of Patent: November 25, 2008
    Assignee: Alkermes, Inc.
    Inventors: Steven G. Wright, Troy Christenson, Thean Y. Yeah, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Henry R. Costantino
  • Polymer-Based Sustained Release Device
    Publication number: 20080260847
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Application
    Filed: April 15, 2004
    Publication date: October 23, 2008
    Applicant: Alkermes, Inc.
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Henry R. Costantino
  • Polymorphic Forms of Naltrexone
    Publication number: 20080227804
    Abstract: This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and combinations thereof. These novel forms of naltrexone impart advantages in pharmaceutical formulations incorporating them, including sustained release, or long acting, formulations.
    Type: Application
    Filed: September 25, 2007
    Publication date: September 18, 2008
    Applicant: ALKERMES, INC.
    Inventors: Harry G. Brittain, David A. Dickason, Joyce Hotz, Shawn L. Lyons, J. Michael Ramstack, Steven G. Wright
  • Polymer-based sustained release device
    Publication number: 20080125351
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Application
    Filed: July 20, 2007
    Publication date: May 29, 2008
    Applicant: Alkermes, Inc.
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Henry R. Costantino
  • Polymer-based sustained release device
    Publication number: 20080125348
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Application
    Filed: July 16, 2007
    Publication date: May 29, 2008
    Applicant: Alkermes, Inc.
    Inventors: Steven G. Wright, Troy Christensen, Thean Y. Yeah, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Henry R. Costantino
  • Polymer-based sustained release device
    Publication number: 20080125349
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Application
    Filed: July 16, 2007
    Publication date: May 29, 2008
    Applicant: Alkermes, Inc.
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeah, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Henry R. Costantino
  • Polymer-based sustained release device
    Publication number: 20080119569
    Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.
    Type: Application
    Filed: July 20, 2007
    Publication date: May 22, 2008
    Applicant: Alkermes, Inc.
    Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Mark Fineman, Christine Smith, John Ong, David M. Lokensgard, Henry R. Costantino
  • Method and apparatus for preparing microparticles using in-line solvent extraction
    Patent number: 7300671
    Abstract: Apparatus and method for preparing microparticles using in-line solvent extraction. An emulsion is formed by combining two phases in a static mixer. The emulsion is combined with an extraction liquid in a blending static mixer. The outflow of the blending static mixer is combined with additional extraction liquid. The additional extraction liquid and the outflow of the blending static mixer can be combined in a vessel, or through the use of a static mixer manifold that includes a plurality of static mixers.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: November 27, 2007
    Assignee: Alkermes, Inc.
    Inventors: Shawn L. Lyons, Steven G. Wright
  • Polymorphic forms of naltrexone
    Patent number: 7279579
    Abstract: This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and combinations thereof. These novel forms of naltrexone impart advantages in pharmaceutical formulations incorporating them, including sustained release, or long acting, formulations.
    Type: Grant
    Filed: June 3, 2004
    Date of Patent: October 9, 2007
    Assignee: Alkermes, Inc.
    Inventors: Harry G. Brittain, David A. Dickason, Joyce Hotz, Shawn L. Lyons, J. Michael Ramstack, Steven G. Wright
  • Preparation of microparticles having improved flowability
    Patent number: 7247319
    Abstract: Methods for preparing microparticles having improved flowability to facilitate processing in automated equipment. Microparticles are conditioned so that a flowability index of the microparticles is greater than about 60. The conditioning preferably includes maintaining the microparticles at a conditioning temperature for a period of time. The conditioning can be used with microparticles containing an active agent, and with placebo microparticles, and it is reversible.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: July 24, 2007
    Assignee: Alkermes, Inc.
    Inventors: J. Michael Ramstack, Steven G. Wright, David A. Dickason
  • Method and apparatus for preparing microparticles using in-line solvent extraction
    Patent number: 6939033
    Abstract: Apparatus and method for preparing microparticles using in-line solvent extraction. An emulsion is formed by combining two phases in a static mixer. The emulsion is combined with an extraction liquid in a blending static mixer. The outflow of the blending static mixer is combined with additional extraction liquid. The additional extraction liquid and the outflow of the blending static mixer can be combined in a vessel, or through the use of a static mixer manifold that includes a plurality of static mixers.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: September 6, 2005
    Assignee: Alkermes Controlled Therapeutics, Inc. II
    Inventors: Shawn L. Lyons, Steven G. Wright
  • Apparatus and method for preparing microparticles
    Patent number: 6861016
    Abstract: Apparatus and method for preparing microparticles. An emulsion is formed by combining two phases in a static mixing assembly. The static mixing assembly preferably includes a preblending static mixer and a manifold. The emulsion flows out of the static mixing assembly into a quench liquid whereby droplets of the emulsion form microparticles. The residence time of the emulsion in the static mixing assembly is controlled to obtain a predetermined particle size distribution of the resulting microparticles.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: March 1, 2005
    Assignee: Alkermes Controlled Therapeutics Inc. II
    Inventors: Shawn L. Lyons, Steven G. Wright
  • Method and apparatus for preparing microparticles using in-line solvent extraction
    Publication number: 20040247688
    Abstract: Apparatus and method for preparing microparticles using in-line solvent extraction. An emulsion is formed by combining two phases in a static mixer. The emulsion is combined with an extraction liquid in a blending static mixer. The outflow of the blending static mixer is combined with additional extraction liquid. The additional extraction liquid and the outflow of the blending static mixer can be combined in a vessel, or through the use of a static mixer manifold that includes a plurality of static mixers.
    Type: Application
    Filed: December 9, 2003
    Publication date: December 9, 2004
    Inventors: Shawn L. Lyons, Steven G. Wright
  • Apparatus and method for preparing microparticles
    Publication number: 20040197469
    Abstract: Apparatus and method for preparing microparticles. An emulsion is formed by combining two phases in a static mixing assembly. The static mixing assembly preferably includes a preblending static mixer and a manifold. The emulsion flows out of the static mixing assembly into a quench liquid whereby droplets of the emulsion form microparticles. The residence time of the emulsion in the static mixing assembly is controlled to obtain a predetermined particle size distribution of the resulting microparticles.
    Type: Application
    Filed: November 17, 2003
    Publication date: October 7, 2004
    Applicant: Alkermes Controlled Therapeutics Inc. II
    Inventors: Shawn L. Lyons, Steven G. Wright
  • Apparatus and method for preparing microparticles
    Patent number: 6713090
    Abstract: Apparatus and method for preparing microparticles. An emulsion is formed by combining two phases in a static mixing assembly. The static mixing assembly preferably includes a preblending static mixer and a manifold. The emulsion flows out of the static mixing assembly into a quench liquid whereby droplets of the emulsion form microparticles. The residence time of the emulsion in the static mixing assembly is controlled to obtain a predetermined particle size distribution of the resulting microparticles.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: March 30, 2004
    Assignee: Alkermas Controlled Therapeutics Inc. II
    Inventors: Shawn L. Lyons, Steven G. Wright