Abstract: In accordance with an embodiment, described herein are systems and methods for providing tiered data storage in cloud infrastructure environments. A data storage service (block store) is adapted to automatically adjust the manner by which the data for a data volume or block volume (data/block volume), associated with a cloud instance, can be stored to meet the requirements of a performance tier. For example, responsive to selection of a particular performance tier, the storage of the data/block volume can be allocated between a first type of data storage associated with a first performance characteristics; and a second type of data storage associated with a second performance characteristics. A graphical user interface enables configuring data/block volumes to use particular performance tiers, and/or to support automatic tuning.

Abstract: This invention is a tubular shaped flying toy comprised of a polypropylene (foam) main cylindrical body with a heavy plastic ring supported front end. The main foam body is held in place to the plastic ring support with the help of rubber bracelet bands that stretch around the outside of the front end of the toy where the foam body stretches onto the hard plastic ring. The toy is thrown with a baseball type throwing motion, and provides a graceful, smooth flight.

Abstract: This invention is a tubular shaped flying toy comprised of a polypropylene (foam) main cylindrical body with a heavy plastic ring supported front end. The main foam body is held in place to the plastic ring support with the help of rubber bracelet bands that stretch around the outside of the front end of the toy where the foam body stretches onto the hard plastic ring. The toy is thrown with a baseball type throwing motion, and provides a graceful, smooth flight.

Abstract: In accordance with an embodiment, described herein are systems and methods for providing tiered data storage in cloud infrastructure environments. A data storage service (block store) is adapted to automatically adjust the manner by which the data for a data volume or block volume (data/block volume), associated with a cloud instance, can be stored to meet the requirements of a performance tier. For example, responsive to selection of a particular performance tier, the storage of the data/block volume can be allocated between a first type of data storage associated with a first performance characteristics; and a second type of data storage associated with a second performance characteristics. A graphical user interface enables configuring data/block volumes to use particular performance tiers, and/or to support automatic tuning.

Abstract: The invention provides a method for treating elevated platelet levels in patients using oligonucleotides in formulations that enhance penetration of the oligonucleotide into cells. Certain oligonucleotides found suitable for use in this method are anitisense oligonucleotides. Of the antisense oligonucleotide that are effective, it has been found that antisense oligonucleotides that inhibit the expression of the raf-1 gene can be used, for example, formulated in liposomes. The method has the advantage that the formulation of oligonucleotide can be administered to human patients and the platelet count will decrease in the absence of additional therapeutic treatment steps, including other chemotherapeutic or radiation treatments.