Abstract: Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.

Abstract: A method is provided that can include activating at least two wireless communication channels in parallel, between a first wireless transceiver and a second wireless transceiver. Each of the at least two wireless communication channels can operate at a different radio carrier frequency, and the first wireless transceiver may be part of a first vehicle. The method can also include transmitting, by the first wireless transceiver, common information in parallel on the at least two wireless communication channels to the second wireless transceiver and deactivating the at least two wireless communication channels.

Abstract: Provided herein are compounds of the Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, X1, X2, X3, X4, Ring D, and E have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.

Abstract: Exemplary systems and methods are directed to generating synthetic data for computer vision. A processing device generates a synthetic three-dimensional (3D) image of an object. A background image is selected, and a composite image is generated by combining the 3D image of the object and the background image. The processing device simulates: reflection or emission of at least one type of radiant energy from the surface of the object and/or the background according to a set of parameters associated with at least one of the object and the background image; and a reflectance or emittance measurement of the at least one type of radiant energy from the surface of the object by a sensor device configured for detecting the at least one type of radiant energy. The processing device generates a plurality of two-dimensional (2D) simulated images of different perspectives of the object based on simulation data.

Abstract: An assembly including a positioning tool that includes a probe affixed to a portion of a grasping tool, wherein a distal tip of the probe protrudes distally from the grasping tool a distance corresponding to a position for placing a magnet with the grasping tool.

Abstract: An obstruction device includes an obstruction disc mounted on a proximal portion of a shaft. Anchoring members are disposed on the shaft on a proximal side of the obstruction disc. The anchoring members include a pair of loops which are orthogonal to each other, one being a longitudinal member and the other a latitudinal member. One or more support struts, which include one or more loops, are disposed on a distal side of the obstruction disc.

Abstract: An assembly including a positioning tool that includes a probe affixed to a portion of a grasping tool, wherein a distal tip of the probe protrudes distally from the grasping tool a distance corresponding to a position for placing a magnet with the grasping tool.

Abstract: Stored information comprising product use information for each of a plurality of mechanical implants is maintained. Data identifying a mechanical implant is received, during a medical procedure. Suitability of the mechanical implant is determined, during the medical procedure, based on the data and the stored information.

Abstract: An assembly including an obstruction device including a proximal obstruction balloon and a distal obstruction balloon mounted on a shaft, the balloons being inflatable via an inflation lumen, and a delivery system that includes an insertion tool and an injection site assembly assembled with one of the balloons, the insertion tool including a connector which is connectable to the injection site assembly and which permits passing tools and injection fluid therethrough.

Abstract: Stored information comprising product use information for each of a plurality of mechanical implants is maintained. Data identifying a mechanical implant is received, during a medical procedure. Suitability of the mechanical implant is determined, during the medical procedure, based on the data and the stored information.

Abstract: Stored information comprising product use information for each of a plurality of mechanical implants is maintained. Data identifying a mechanical implant is received, during a medical procedure. Suitability of the mechanical implant is determined, during the medical procedure, based on the data and the stored information.

Abstract: An obstruction device (10) including an obstruction disc (12) mounted on a proximal portion of a shaft (14), the disc including an inner radial portion (16) and an outer radial portion (18), wherein the outer radial portion is more bendable than the inner radial portion.

Abstract: An assembly including an obstruction device including a proximal obstruction balloon and a distal obstruction balloon mounted on a shaft, the balloons being inflatable via an inflation lumen, and a delivery system that includes an insertion tool and an injection site assembly assembled with one of the balloons, the insertion tool including a connector which is connectable to the injection site assembly and which permits passing tools and injection fluid therethrough.

Abstract: An assembly including a positioning tool that includes a probe affixed to a portion of a grasping tool, wherein a distal tip of the probe protrudes distally from the grasping tool a distance corresponding to a position for placing a magnet with the grasping tool.

Abstract: An endoscopic delivery system including an endoscope including at least one imaging device and a working channel, and a catheter arranged to pass through the working channel, wherein the catheter is formed with an observation window on a side portion thereof, the window being in a line of sight of the at least one imaging device.

Abstract: An obstruction device including a proximal obstruction balloon and a distal obstruction balloon mounted on a shaft, wherein a neck portion of said shaft provides a gap between a distal end of said proximal obstruction balloon and a proximal end of said distal obstruction balloon.

Abstract: A method for creating an anastomosis between a stomach and a portion of a small intestine, and simultaneously controlling passage of stomach contents through a pylorus with a pylorus plug that includes a valve operative to either close or at least partially open passageway through the pylorus.

Abstract: Stored information comprising product use information for each of a plurality of mechanical implants is maintained. Data identifying a mechanical implant is received, during a medical procedure. Suitability of the mechanical implant is determined, during the medical procedure, based on the data and the stored information.

Abstract: A anteromedial approach to arthroplasty on a knee joint of a patient. The method of arthroplasty includes an arthrotomy that includes dissecting from medial to the tibial tubercle and around the medial border of the patella and up to the proximal border of the patella.

Abstract: Integrated telephone with an xDSL-modem (2), comprising a splitter unit (6) for separating telephone signals received via a telephone line (9) in a low-frequency band from data signals received in a high-frequency band via the telephone line (9), a telephone set (3) connected to the splitter unit (6) for the transmission of telephone signals in the low-frequency band; and a high-speed xDSL-modem (2) connected to the splitter unit (6) for the transmission of data signals in the high-frequency band.