Abstract: Disclosed herein is a system and a method of providing access to at least one password protected device (D1-D5) via a password management system (100). The password management system (100) comprises first and second password management servers (200), each comprising a memory for storing an active password and a reserve password. The first and second password management servers (200) communicate the active and reserve passwords via a communication link (220). Either one of the first and second password management servers (200) requests access to the password protected device using the active password stored in the memory, and if the active password does not provide access, requests access using the reserve password.

Abstract: The present technology provides the crystalline phosphate, malonate, and malate salts of 3-(2-amino-1,3-benzoxazol-5-yl)-1-(1,3-dimethylbutyl)pyrazolo[3,4-d]pyrimidine-4,6-diamine. The present technology further provides methods for preparing the various forms, compositions containing them, and methods related to modulation of mTOR. In particular, the present crystalline compounds and compositions may be used to treat mTOR-mediated disorders and conditions, including, e.g., dermatological disorders related to a disorder of keratinization with a proliferative, inflammatory and/or immuno-allergic component.

Abstract: A binary array ink jet printhead assembly includes a cavity for containing ink, nozzle orifices in fluid communication with the cavity for passing the ink from the cavity to form droplets, the nozzle orifices extending along a length of the cavity, and an electrode assembly. The electrode assembly includes a front face configured to be disposed generally parallel to a plurality of droplet paths of droplets from the nozzle orifices. A plurality of charge electrodes are disposed on the front face, each charge electrode corresponding to a droplet path and disposed parallel to the droplet path. Circuitry is disposed on the electrode assembly, wherein each electrode is electrically connected to the circuitry. The circuitry is further in electrical connection to a connector for connecting the electrode assembly to a controller for the printhead.

Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of mechanistic target of rapamycin (mTOR).

Abstract: Novel compounds having formula (I) and methods of using these compounds to treat diseases, conditions, and disorders are described.

Abstract: A method of preparing a hydrogel product including crosslinked glycosaminoglycan molecules, said method including: i) providing a glycosaminoglycan crosslinked by amide bonds, wherein the crosslinked glycosaminoglycans include residual amine groups; and ii) acylating residual amine groups of the crosslinked glycosaminoglycans provided in i) to form acylated crosslinked glycosaminoglycans.

Abstract: Disclosed herein is a system and a method of providing access to at least one password protected device (D1-D5) via a password management system (100). The password management system (100) comprises first and second password management servers (200), each comprising a memory for storing an active password and a reserve password. The first and second password management servers (200) communicate the active and reserve passwords via a communication link (220). Either one of the first and second password management servers (200) requests access to the password protected device using the active password stored in the memory, and if the active password does not provide access, requests access using the reserve password.

Abstract: A method of preparing a hydrogel product including crosslinked glycosaminoglycan molecules, said method including: i) providing a glycosaminoglycan crosslinked by amide bonds, wherein the crosslinked glycosaminoglycans include residual amine groups; and ii) acylating residual amine groups of the crosslinked glycosaminoglycans provided in i) to form acylated crosslinked glycosaminoglycans.

Abstract: A services platform acts as an intermediary between an existing enterprise analytic environment, and one or more underlying cloud service providers. The platform provides enterprise “big data-as-a-service,” by which an enterprise can seamlessly and easily provision new capacity for processing its analytic workload, and migrate data sources (e.g., data warehouse marts, enterprise data warehouses, analytic sandboxes, and the like) to the cloud for processing. The platform provides end-to-end enterprise class manageability of enterprise data assets, from data collection, aggregation, movement, staging and processing, all while providing service levels, security, access and governance. The platform integrates directly but seamlessly into the enterprise analytic stack, and existing analytics applications work as normal. The platform provides a way for the enterprise to translate its workloads into clusters of compute resources that meet its service level requirements.

Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.

Abstract: A new hydrogel made of crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boronic acid or boroxole derivatives leading to new benefits. Glycosaminoglycans that are crosslinked via an alkoxyboronate ester anion formed between a diol portion of a diol-functional moiety grafted to a first glycosaminoglycan and a boronate hemiester grafted to a second glycosaminoglycan.

Abstract: Disclosed herein is a system and a method of providing access to at least one password protected device (D1-D5) via a password management system (100). The password management system (100) comprises first and second password management servers (200), each comprising a memory for storing an active password and a reserve password. The first and second password management servers (200) communicate the active and reserve passwords via a communication link (220). Either one of the first and second password management servers (200) requests access to the password protected device using the active password stored in the memory, and if the active password does not provide access, requests access using the reserve password.

Abstract: A method of preparing a hydrogel product including crosslinked glycosaminoglycan molecules, said method including: i) providing a glycosaminoglycan crosslinked by amide bonds, wherein the crosslinked glycosaminoglycans include residual amine groups; and ii) acylating residual amine groups of the crosslinked glycosaminoglycans provided in i) to form acylated crosslinked glycosaminoglycans.

Abstract: A method of preparing a hydrogel product including crosslinked glycosaminoglycan molecules, said method including: i) providing a glycosaminoglycan crosslinked by amide bonds, wherein the crosslinked glycosaminoglycans include residual amine groups; and ii) acylating residual amine groups of the crosslinked glycosaminoglycans provided in i) to form acylated crosslinked glycosaminoglycans.

Abstract: Various embodiments include devices, systems, and methods for managing storage of video in response to an event in a body-worn video recording device. A body-worn video recording device may continuously store images captured by the camera in the rolling buffer memory, and copy images stored on the rolling buffer memory and storing images captured by the camera in a non-volatile memory in response to determining that a trigger event has occurred. A network computing device may receive from a first body-worn video recording device a signal that a trigger event has occurred, select one or more second body-worn video recording devices in response to receiving the signal that the trigger event has occurred, and send activation messages to the selected one or more second body-worn video recording devices to store images from a respective rolling buffer memory and subsequently captured images in a non-volatile memory.

Abstract: The technology disclosed relates to modularized beverage holder for actively cooling beverages. The modularized beverage holder includes a sleeve shaped beverage container receiver having a unibody construction comprising an insulating material, an interior opening adapted to receive beverage containers of varying sizes and materials, a bottom portion adapted to receive and provide support for beverage containers inserted into the interior opening of the sleeve shaped beverage container receiver, and a sidewall including an interior surface, an exterior surface and one or more via holes. The beverage holder further includes a first modular engine for actively cooling beverages, the first modular engine being mounted to the sleeve shaped beverage container receiver, and the first modular engine including a first thermal conductor member, and a first active temperature control system.

Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.

Abstract: A multiple well device for processing fluid samples is provided, comprising a plate including a plurality of wells, each well including a first sub-well and a second sub-well, separated by an individual dialysis membrane; each individual dialysis membrane having a top end and a bottom end, having a continuous taper from the top end to the bottom end, each first sub-well and each second sub-well having an upper end and a lower end, and side walls, wherein one side wall is a common side wall shared by the first sub-well and the second sub-well, the common side wall having a continuous tapered cut-out with the individual dialysis membrane fluid-tightly sealed in the continuous tapered cut-out.

Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.

Abstract: A services platform acts as an intermediary between an existing enterprise analytic environment, and one or more underlying cloud service providers. The platform provides enterprise “big data-as-a-service,” by which an enterprise can seamlessly and easily provision new capacity for processing its analytic workload, and migrate data sources (e.g., data warehouse marts, enterprise data warehouses, analytic sandboxes, and the like) to the cloud for processing. The platform provides end-to-end enterprise class manageability of enterprise data assets, from data collection, aggregation, movement, staging and processing, all while providing service levels, security, access and governance. The platform integrates directly but seamlessly into the enterprise analytic stack, and existing analytics applications work as normal. The platform provides a way for the enterprise to translate its workloads into clusters of compute resources that meet its service level requirements.