Abstract: The present invention is a board game with a board divided into four sectors with numbered squares within to determine the distance a playing piece can move or attack. The squares are organized on the board in rows and columns. There are two sets of playing pieces, one for each player or team of players. The two sets of playing pieces have different types of playing pieces for different strategical moves. At least a tank piece, a special forces piece, a soldier piece, an aircraft piece, a decoy piece, a wall piece, and a valley piece are in the set. Status cards designate a regular status value to the set of playing pieces for a player or team and designate a sector status value to each of the four sectors on the board. A player wins when the opposing player has no more playing pieces.

Abstract: The present invention provides methods, compositions, and kits for treating anxiety-related disorders, including OCD and SAD, and for reducing anxiety, obsessive behavior, or compulsive behavior in subjects in need thereof.

Abstract: The invention relates to compounds of formula I wherein R1, R2 and - - - - - are as defined herein, pharmaceutical compositions comprising the compounds and methods of treating COVID-19 in a patient by administering therapeutically effective amounts of the compounds and methods of inhibiting or preventing replication of SARS-CoV-2 with the compounds.

Abstract: The present inventions provide compositions and methods for modulating tumors in non-human mammals using a tyrosine derivative.

Abstract: The present invention provides methods, compositions, and kits for treating intestinal hyperpermeability in a subject in need thereof, including conditions such as hyperglycemia and underlying diseases such as diabetes, autism, fibromyalgia, inflammatory bowel disease (IBD), graft versus host disease (GVHD), HIV/AIDS, multiple organ dysfunction syndrome, irritable bowel syndrome (IBS), celiac disease, eczema, psoriasis, acute pancreatitis, Parkinson's disease, depression, chronic fatigue syndrome, asthma, multiple sclerosis, arthritis, ankylosing spondylitis, nonalcoholic fatty liver disease, alcoholic cirrhosis, environmental enteropathy, or kwashiorkor.

Abstract: The invention provides compositions and methods of treating autism. Specifically, the invention relates to treating the core symptoms of autism by administering ?-methyl-DL-tyrosine.

Abstract: The disclosure is directed to methods of using hydrophilic bile acids for the treatment of viral infections.

Abstract: The present disclosure is directed to methods of treating conditions characterized by insulin deficiency in animals by trans dermal insulin administration.

Abstract: The present disclosure is directed to methods, compositions, and kits for treating amyotrophic lateral sclerosis.

Abstract: The invention provides compositions and methods of treating autism. Specifically, the invention relates to treating the core symptoms of autism by administering ?-methyl-DL-tyrosine.

Abstract: A business-strategy game and method of playing a business-strategy game is presented herein. The game includes a playing defining a path of game spaces through which the players of the game traverse with corresponding game pieces. A number of the game spaces are associated with financial activities representative of properties and merchants. Each player includes a power status and at least one refund status, wherein said at least one power status is capable of being changed throughout said game. The power status is used to define requirements for financial activities including amounts owed for purchasing goods and services and whether previously accrued credit amounts are due.

Abstract: The disclosure is directed to methods of using TUDCA, or a pharmaceutically acceptable salt thereof, or a derivative thereof, for the treatment of SARS-CoV-2 infections.

Abstract: The present invention provides methods, compositions, and kits for treating anxiety-related disorders, including OCD and SAD, and for reducing anxiety, obsessive behavior, or compulsive behavior in subjects in need thereof.

Abstract: Disclosed are methods for treating cancer by reduction of glycogen stores and administering tyrosine derivatives.

Abstract: Compositions and kits comprising a tyrosine hydroxylase inhibitor and an anticancer agent that is chemically bonded to, or physically associated with, the tyrosine hydroxylase inhibitor are provided. Also provided are methods for reducing cell proliferation in a subject comprising administering to a subject in need thereof a composition comprising a tyrosine hydroxylase inhibitor and an anticancer agent that is chemically bonded to, or physically associated with, the tyrosine hydroxylase inhibitor.

Abstract: The present invention provides methods, compositions, and kits for treating anxiety-related disorders, including OCD and SAD, and for reducing anxiety, obsessive behavior, or compulsive behavior in subjects in need thereof.

Abstract: The present invention provides methods, compositions, and kits for treating retinopathy, including diabetic retinopathy and macular degeneration, in a subject in need.

Abstract: The invention relates to tyrosine hydroxylase inhibitor compositions and methods of preparing and administering thereof. Specifically, the invention relates to an oral chewable formulation of a tyrosine hydroxylase inhibitor, particularly ?-methyl-DL-tyrosine.

Abstract: The present disclosure is directed to percutaneous compositions containing an antiseptic, an antibiotic, an antifungal agent, an antihelminth agent, an antiviral agent, or an NSAID.

Abstract: The invention relates to tyrosine hydroxylase inhibitor compositions and methods thereof. Specifically, the invention relates to a sustained release formulation of a tyrosine hydroxylase inhibitor, particularly ?-methyl-para-tyrosine.