Patents by Inventor Steven Howard Sacks

Steven Howard Sacks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9255263
    Abstract: A soluble compound for preventing or reducing blood coagulation comprising an antithrombotic agent and a membrane binding element, wherein the antithrombotic agent has a weight of less than about 5,000 daltons. Also disclosed is a soluble compound for preventing or reducing blood coagulation comprising an anticoagulant joined to a membrane binding element via a joining element, wherein the joining element between the anticoagulant and the membrane binding element is less than about 10,000 daltons in weight. These compounds can be used in therapy and, in particular, in preventing or reducing blood coagulation. As a result, a method of treatment is provided comprising administering an effective amount of the compounds to a subject to prevent or reduce blood coagulation as well as a method of perfusing an organ, tissue or cell comprising contacting the compounds with the organ, tissue or cell to prevent or reduce blood coagulation.
    Type: Grant
    Filed: September 6, 2010
    Date of Patent: February 9, 2016
    Assignees: King's College London, Imperial Innovations Limited
    Inventors: Richard Anthony Godwin Smith, Steven Howard Sacks, Anthony Dorling
  • Publication number: 20120232014
    Abstract: A soluble compound for preventing or reducing blood coagulation comprising an antithrombotic agent and a membrane binding element, wherein the antithrombotic agent has a weight of less than about 5,000 daltons. Also disclosed is a soluble compound for preventing or reducing blood coagulation comprising an anticoagulant joined to a membrane binding element via a joining element, wherein the joining element between the anticoagulant and the membrane binding element is less than about 10,000 daltons in weight. These compounds can be used in therapy and, in particular, in preventing or reducing blood coagulation. As a result, a method of treatment is provided comprising administering an effective amount of the compounds to a subject to prevent or reduce blood coagulation as well as a method of perfusing an organ, tissue or cell comprising contacting the compounds with the organ, tissue or cell to prevent or reduce blood coagulation.
    Type: Application
    Filed: September 6, 2010
    Publication date: September 13, 2012
    Applicants: IMPERIAL INNOVATIONS LIMITED, KING'S COLLEGE LONDON
    Inventors: Richard Anthony Godwin Smith, Steven Howard Sacks, Anthony Dorling
  • Patent number: 7888318
    Abstract: This invention relates to formulations of polypeptides and their derivatives that act as inhibitors or regulators of the immune or coagulation systems and are of use in organ transplantation. It provides solutions which include, for example, complement inhibitors or regulators of T- or B-lymphocyte function in modified molecular forms that can be used to perfuse and modify organs prior to transplantation or to store organs prior to transplantation, and to localise agents on organs.
    Type: Grant
    Filed: March 8, 2000
    Date of Patent: February 15, 2011
    Assignee: Adprotech Limited
    Inventors: Richard Anthony Godwin Smith, Julian Roy Pratt, Steven Howard Sacks