Patents by Inventor Steven Isakoff

Steven Isakoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination treatments with sonic hedgehog inhibitors
    Patent number: 10220091
    Abstract: Methods for treating cancer using a combination of an inhibitor of the sonic hedgehog signaling pathway (e.g., LDE225) with radiation and a tumor antigen-specific monoclonal antibody (e.g., heat shock protein (HSP) glucose regulated protein of 94000 daltons (Grp94)-specific mAb W9, or chondroitin sulfate proteoglycan 4 (CSPG4)-targeted mAbs), or with a BRAF inhibitor, e.g., in BRAF inhibitor resistant cancers.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: March 5, 2019
    Assignee: The General Hospital Corporation
    Inventors: Francesco Sabbatino, Yangyang Wang, Xinhui Wang, Steven Isakoff, Cristina Ferrone, Joe Schwab, Soldano Ferrone
  • Combination Treatments with Sonic Hedgehog Inhibitors
    Publication number: 20160045598
    Abstract: Methods for treating cancer using a combination of an inhibitor of the sonic hedgehog signaling pathway (e.g., LDE225) with radiation and a tumor antigen-specific monoclonal antibody (e.g., heat shock protein (HSP) glucose regulated protein of 94000 daltons (Grp94)-specific mAb W9, or chondroitin sulfate proteoglycan 4 (CSPG4)-targeted mAbs), or with a BRAF inhibitor, e.g., in BRAF inhibitor resistant cancers.
    Type: Application
    Filed: April 3, 2014
    Publication date: February 18, 2016
    Inventors: Francesco Sabbatino, Yangyang Wang, Xinhui Wang, Steven Isakoff, Cristina Ferrone, Joe Schwab, Soldano Ferrone