Patents by Inventor Steven J. Brenek

Steven J. Brenek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for preparing SGLT2 inhibitors
    Patent number: 9573959
    Abstract: This invention relates to methods for preparing a sodium-glucose transporter 2 (SGLT2) inhibitor, a cocrytalline SGLT2 and (S)-5-oxopyrrolidine-2-carboxylic acid (L-PGA) complex, and intermediates useful in the preparation of the said SGLT2 inhibitor.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: February 21, 2017
    Assignee: MSD International GMBH
    Inventors: Steven J. Brenek, Stephane Caron, Jade D. Nelson, Mark E. Webster, Rodney Matthew Weekly
  • METHODS FOR PREPARING SGLT2 INHIBITORS
    Publication number: 20160046646
    Abstract: This invention relates to methods for preparing a sodium-glucose transporter 2 (SGLT2) inhibitor, a cocrytalline SGLT2 and (S)-5-oxopyrrolidine-2-carboxylic acid (L-PGA) complex, and intermediates useful in the preparation of the said SGLT2 inhibitor.
    Type: Application
    Filed: March 10, 2014
    Publication date: February 18, 2016
    Inventors: Steven J. Brenek, Stephane Caron, Jade D. Nelson, Mark E. Webster, Rodney Matthew Weekly
  • Crystallization method and apparatus using an impinging plate assembly
    Publication number: 20040098839
    Abstract: A crystallization process for generating a pharmaceutical product from solutions of pharmaceutically active compounds or their reactive intermediates employs fluid jet streams containing pharmaceutically active ingredients, appropriate anti-solvents and/or their reactive intermediates capable of producing a pharmaceutical product with desired particle size characteristics upon mixing, chemical reaction, nucleation and precipitation. The jet streams are directed towards an impinging plate, and mixing occurs as the jet streams impinge the plate at a desired area of impact.
    Type: Application
    Filed: November 13, 2003
    Publication date: May 27, 2004
    Applicant: Pfizer Inc.
    Inventors: Steven J. Brenek, David J. Am Ende