Patents by Inventor Steven J. Chmura

Steven J. Chmura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and method for multi-site radiotherapy
    Patent number: 11986670
    Abstract: A method of radiating a plurality of masses in a patient is provided, including receiving a three-dimensional model of the patient, the model including respective locations of a plurality of OARs, receiving a set of locations in the model corresponding to the masses, respective prescribed radiation dosages for the masses, and respective radiation limits for the OARs. The method includes computing a candidate set of beams having respective beam paths that travel through at least one of the masses. The method includes scoring the candidate set of beams based on respective dosages provided to the masses, respective dosages provided to the OARs, and beams in a set of selected beams for treatment, adding a best-scoring beam among the candidate set of beams to the set of selected beams, and radiating the masses using the set of selected beams.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: May 21, 2024
    Assignee: THE UNIVERSITY OF CHICAGO
    Inventors: Steven J Chmura, Shan Lu, Ralph R. Weichselbaum
  • SYSTEM AND METHOD FOR MULTI-SITE RADIOTHERAPY
    Publication number: 20220047892
    Abstract: A method of radiating a plurality of masses in a patient is provided, including receiving a three-dimensional model of the patient, the model including respective locations of a plurality of OARs, receiving a set of locations in the model corresponding to the masses, respective prescribed radiation dosages for the masses, and respective radiation limits for the OARs. The method includes computing a candidate set of beams having respective beam paths that travel through at least one of the masses. The method includes scoring the candidate set of beams based on respective dosages provided to the masses, respective dosages provided to the OARs, and beams in a set of selected beams for treatment, adding a best-scoring beam among the candidate set of beams to the set of selected beams, and radiating the masses using the set of selected beams.
    Type: Application
    Filed: September 18, 2019
    Publication date: February 17, 2022
    Inventors: Steven J Chmura, Shan Lu, Ralph R. Weichselbaum
  • Chelerythrine-based therapies for cancer
    Patent number: 6426351
    Abstract: Chelerythrine is an effective inhibitor of solid tumor growth and is extremely cytotoxic in combination with chemotherapeutic agents that directly damage DNA.
    Type: Grant
    Filed: August 11, 2000
    Date of Patent: July 30, 2002
    Assignees: Dana-Farber Cancer, Inc., Arch Development Corporation
    Inventors: Ralph R. Weichselbaum, Donald W. Kufe, Steven J. Chmura, Mary E. Dolan