Patents by Inventor Steven J. Conrad

Steven J. Conrad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION FOR TREATING CANCEROUS CELLS AND A METHOD THEREFOR
    Publication number: 20200114024
    Abstract: A composition for treating cancerous cells in a subject having an immune system includes a virus in the Yatapoxvirus genus having at least one mutation. In one embodiment, the mutation results in suppressed expression of a TNF binding protein by the virus. In another embodiment, the mutation results in suppressed expression of thymidine kinase (“TK”) by the virus. In another embodiment, the mutation arms the virus with a transgene to express a bacterial flagellin. The mutations can be present singly or in combination. Additional aspects include a method of treating cancerous cells with a composition as described herein, and a method of delivering at least one gene to cancerous cells in a subject.
    Type: Application
    Filed: October 7, 2019
    Publication date: April 16, 2020
    Inventors: Karim Essani, David Jeng, Steven J. Conrad
  • Composition for treating cancerous cells and a method therefor
    Patent number: 10434189
    Abstract: A composition for treating cancerous cells in a subject having an immune system includes a virus in the Yatapoxvirus genus having at least one mutation. In one embodiment, the mutation results in suppressed expression of a TNF binding protein by the virus. In another embodiment, the mutation results in suppressed expression of thymidine kinase (“TK”) by the virus. In another embodiment, the mutation arms the virus with a transgene to express a bacterial flagellin. The mutations can be present singly or in combination. Additional aspects include a method of treating cancerous cells with a composition as described herein, and a method of delivering at least one gene to cancerous cells in a subject.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: October 8, 2019
    Assignee: The Board of Trustees of Western Michigan University
    Inventors: Karim Essani, David Jeng, Steven J. Conrad
  • COMPOSITION FOR TREATING CANCEROUS CELLS AND A METHOD THEREFOR
    Publication number: 20170165378
    Abstract: A composition for treating cancerous cells in a subject having an immune system includes a virus in the Yatapoxvirus genus having at least one mutation. In one embodiment, the mutation results in suppressed expression of a TNF binding protein by the virus. In another embodiment, the mutation results in suppressed expression of thymidine kinase (“TK”) by the virus. In another embodiment, the mutation arms the virus with a transgene to express a bacterial flagellin. The mutations can be present singly or in combination. Additional aspects include a method of treating cancerous cells with a composition as described herein, and a method of delivering at least one gene to cancerous cells in a subject.
    Type: Application
    Filed: January 17, 2017
    Publication date: June 15, 2017
    Applicant: Western Michigan University Research Foundation
    Inventors: Karim Essani, David Jeng, Steven J. Conrad