Patents by Inventor Steven J. Kline

Steven J. Kline has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metal containing 8-hydroxyquinoline chelating agents
    Patent number: 5245026
    Abstract: The present invention provides linear, cyclic and trifurcate tri- and tetramine backbone multidentate chelating agents based on the 8-hydroxyquinoline chelating unit. The chelating agents may optionally be substituted with a substrate reactive moiety and antibody-metal ion conjugates may be produced for in vivo diagnostic and therapeutic methods.
    Type: Grant
    Filed: May 21, 1991
    Date of Patent: September 14, 1993
    Assignees: Abbott Laboratories, Tobishi Yakuhin Kogyo Kabushiki Kaisha
    Inventors: David K. Johnson, Steven J. Kline
  • Bifunctional chelating agents
    Patent number: 5227474
    Abstract: The present invention provides bifunctional chelating agents comprising a unique substrate reactive moiety incorporated into a carboxymethyl arm of a polyaminopolycarboxylate chelating framework capable of forming stable complexes with metal ions.
    Type: Grant
    Filed: May 28, 1991
    Date of Patent: July 13, 1993
    Assignee: Abbott Laboratories
    Inventors: David K. Johnson, Steven J. Kline
  • Bifunctional chelating agents
    Patent number: 5057302
    Abstract: The present invention provides bifunctional chelating agents comprising a unique substrate reactive moiety incorporated into a carboxymethyl arm of a polyaminopolycarboxylate chelating framework capable of forming stable complexes with metal ions.
    Type: Grant
    Filed: January 4, 1988
    Date of Patent: October 15, 1991
    Assignee: Abbott Laboratories
    Inventors: David K. Johnson, Steven J. Kline
  • 8-hydroxyquinoline chelating agents
    Patent number: 5021567
    Abstract: The present invention provides linear, cyclic and trifurcate tri- and tetramine backbone multidentate chelating agents based on the 8-hydroxyquinoline chelating unit. The chelating agents may optionally be substituted with a substate reactive moiety and antibody-metal ion conjugates may be produced for in vivo diagnostic and therapeutic methods.
    Type: Grant
    Filed: September 24, 1987
    Date of Patent: June 4, 1991
    Assignee: Abbott Laboratories
    Inventors: David K. Johnson, Steven J. Kline