Patents by Inventor Steven J. M. Jones

Steven J. M. Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9552457
    Abstract: Methods of “reprogramming” epigenetic mark readers or erasers to recognize epigenetic marks other than their cognate (or natural) marks are provided. Reprogramming the reader or eraser can offset the effects of aberrant writer activity (for example, loss of function or overactivity) that can contribute to certain diseases states, such as cancer. The use of the reprogramming compounds identified by these methods in the treatment of such disease states is also provided. Exemplary mark readers that can be targeted by these methods include BPTF and CBX2.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: January 24, 2017
    Assignee: BRITISH COLUMBIA CANCER AGENCY BRANCH
    Inventors: Steven J. M. Jones, Oleksandr Yakovenko, Silvia Thoene, Pierre Yulmin Cheung, Jianghong An
  • Publication number: 20150154345
    Abstract: Methods of “reprogramming” epigenetic mark readers or erasers to recognize epigenetic marks other than their cognate (or natural) marks are provided. Reprogramming the reader or eraser can offset the effects of aberrant writer activity (for example, loss of function or overactivity) that can contribute to certain diseases states, such as cancer. The use of the reprogramming compounds identified by these methods in the treatment of such disease states is also provided. Exemplary mark readers that can be targeted by these methods include BPTF and CBX2.
    Type: Application
    Filed: February 27, 2013
    Publication date: June 4, 2015
    Inventors: Steven J. M. Jones, Oleksandr Yakovenko, Silvia Thoene, Pierre Yulmin Cheung, Jianghong An