Patents by Inventor Steven J. Projan

Steven J. Projan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of expression of beta-lactamase using esters of fatty acid alcohols
    Patent number: 5633245
    Abstract: A class of chemical compounds comprising fatty acid ester derivatives used to inhibit beta-lactamase production by infectious bacteria. These inhibitors have been found to retard the resistance of certain strains of bacteria to beta-lactam antibiotics, such as penicillin, by interfering with the transcription of the beta-lactamase gene and precluding expression of beta-lactamase. In accordance therewith, these inhibitors permit effective treatment of infections of otherwise resistive bacteria with antibiotics.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 27, 1997
    Assignee: Public Health Research Institute
    Inventors: Susan Brown-Skrobot, Richard P. Novick, Steven J. Projan
  • Inhibition of expression of beta-lactamase using esters of fatty acid alcohols
    Patent number: 5466685
    Abstract: A class of chemical compounds comprising fatty acid ester derivatives used to inhibit beta-lactamase production by infectious bacteria. These inhibitors have been found to retard the resistance of certain strains of bacteria to beta-lactam antibiotics, such as penicillin, by interfering with the transcription of the beta-lactamase gene and precluding expression of beta-lactamase. In accordance therewith, these inhibitors permit effective treatment of infections of otherwise resistive bacteria with antibiotics.
    Type: Grant
    Filed: May 13, 1993
    Date of Patent: November 14, 1995
    Assignee: Johnson & Johnson
    Inventors: Susan Brown-Skrobot, Richard P. Novick, Steven J. Projan
  • Pharmaceutical bacteriocin compositions and methods for using the same
    Patent number: 5334582
    Abstract: Compositions comprising lanthionine-containing bacteriocins such as nisin in combination with a chelator act as bactericides in low pH environments. In a preferred embodiment pharmaceutical preparations containing the compositions are used for the control of bacteria responsible for disorders of the gastrointestinal tract.
    Type: Grant
    Filed: July 6, 1993
    Date of Patent: August 2, 1994
    Assignee: Applied Microbiology, Inc.
    Inventors: Peter Blackburn, Steven J. Projan, Edward B. Goldberg
  • Pharmaceutical bacteriocin compositions and methods for using the same
    Patent number: 5304540
    Abstract: Compositions comprising lanthionine-containing bacteriocins such as nisin act as bactericides under conditions such as those found in the gastrointestinal tract. In a preferred embodiment pharmaceutical preparations containing the compositions are used for the control of bacteria responsible for disorders of the gastrointestinal tract.
    Type: Grant
    Filed: July 6, 1993
    Date of Patent: April 19, 1994
    Assignee: Applied Microbiology, Inc.
    Inventors: Peter Blackburn, Steven J. Projan, Edward B. Goldberg