Patents by Inventor Steven J. Richards

Steven J. Richards has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
    Patent number: 11680034
    Abstract: Disclosed herein are compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging, or for modulating one or more energy biomarkers, normalizing one or more energy biomarkers, or enhancing one or more energy biomarkers, wherein the compounds are tocopherol quinone derivatives. Further disclosed are compounds, compositions, and methods for treatment of, or prophylaxis against, radiation exposure.
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: June 20, 2023
    Assignee: PTC Therapeutics, Inc.
    Inventors: Andrew W. Hinman, Steven J. Richards
  • NAPHTHOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS
    Publication number: 20230002324
    Abstract: Disclosed herein are naphthoquinone derivative compounds of the formula shown below, compositions thereof, and methods of using such compounds and compositions for treating or suppressing oxidative stress disorders and/or neurodegenerative disorders and/or for inhibiting ferroptosis.
    Type: Application
    Filed: June 13, 2020
    Publication date: January 5, 2023
    Inventors: Maulen M. UTEULIYEV, Lianhe SHU, Steven J. RICHARDS, Alexander A. WARKENTIN, Dana DAVIS
  • METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS
    Publication number: 20220257533
    Abstract: Compounds, compositions, and methods for treatment of, or prophylaxis against, inflammation and/or oxidative stress are disclosed.
    Type: Application
    Filed: November 29, 2021
    Publication date: August 18, 2022
    Inventors: Guy M. MILLER, Jeffery K. TRIMMER, William SHRADER, Andrew W. HINMAN, Charles R. HOLST, Joey C. LATHAM, Joel J. BRUEGGER, Kevin P. MCCUSKER, Gözde ULAS, Dana DAVIS, Amanda H. KAHN-KIRBY, Edgar P. LEE, Stephanie A. MALONE, Steven J. RICHARDS, Matthew B. KLEIN
  • FLUOROALKYL, FLUOROALKOXY, PHENOXY, HETEROARYLOXY, ALKOXY, AND AMINE 1,4-BENZOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS
    Publication number: 20210238119
    Abstract: Disclosed herein are compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging, or for modulating one or more energy biomarkers, normalizing one or more energy biomarkers, or enhancing one or more energy biomarkers, wherein the compounds are tocopherol quinone derivatives. Further disclosed are compounds, compositions, and methods for treatment of, or prophylaxis against, radiation exposure.
    Type: Application
    Filed: April 12, 2021
    Publication date: August 5, 2021
    Inventors: Andrew W. Hinman, Steven J. Richards
  • Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
    Patent number: 10981855
    Abstract: Disclosed herein are compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging, or for modulating one or more energy biomarkers, normalizing one or more energy biomarkers, or enhancing one or more energy biomarkers, wherein the compounds are tocopherol quinone derivatives. Further disclosed are compounds, compositions, and methods for treatment of, or prophylaxis against, radiation exposure.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: April 20, 2021
    Assignee: PTC THERAPEUTICS, INC.
    Inventors: Andrew W. Hinman, Steven J. Richards
  • FLUOROALKYL, FLUOROALKOXY, PHENOXY, HETEROARYLOXY, ALKOXY, AND AMINE 1,4-BENZOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS
    Publication number: 20200331835
    Abstract: Disclosed herein are compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging, or for modulating one or more energy biomarkers, normalizing one or more energy biomarkers, or enhancing one or more energy biomarkers, wherein the compounds are tocopherol quinone derivatives. Further disclosed are compounds, compositions, and methods for treatment of, or prophylaxis against, radiation exposure.
    Type: Application
    Filed: July 6, 2020
    Publication date: October 22, 2020
    Inventors: Andrew W. HINMAN, Steven J. RICHARDS
  • Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
    Patent number: 10703701
    Abstract: Disclosed herein are compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging, or for modulating one or more energy biomarkers, normalizing one or more energy biomarkers, or enhancing one or more energy biomarkers, wherein the compounds are tocopherol quinone derivatives. Further disclosed are compounds, compositions, and methods for treatment of, or prophylaxis against, radiation exposure.
    Type: Grant
    Filed: December 17, 2016
    Date of Patent: July 7, 2020
    Assignee: PTC THERAPEUTICS, INC.
    Inventors: Andrew W. Hinman, Steven J. Richards
  • METHODS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND OXIDATIVE STRESS
    Publication number: 20200121618
    Abstract: Compounds, compositions, and methods for treatment of, or prophylaxis against, inflammation and/or oxidative stress are disclosed.
    Type: Application
    Filed: April 14, 2018
    Publication date: April 23, 2020
    Inventors: Guy M. MILLER, Jeffery K. TRIMMER, William D. SHRADER, Andrew W. HINMAN, Charles R. HOLST, Joey C. LATHAM, Joel J. BRUEGGER, Kevin P. MCCUSKER, Gozde ULAS, Dana DAVIS, Amanda H. KAHN-KIRBY, Edgar P. LEE, Stephanie A. MALONE, Steven J. RICHARDS, Matthew B. KLEIN
  • FLUOROALKYL, FLUOROALKOXY, PHENOXY, HETEROARYLOXY, ALKOXY, AND AMINE 1,4-BENZOQUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS
    Publication number: 20180370892
    Abstract: Disclosed herein are compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging, or for modulating one or more energy biomarkers, normalizing one or more energy biomarkers, or enhancing one or more energy biomarkers, wherein the compounds are tocopherol quinone derivatives. Further disclosed are compounds, compositions, and methods for treatment of, or prophylaxis against, radiation exposure.
    Type: Application
    Filed: December 17, 2016
    Publication date: December 27, 2018
    Inventors: Andrew W. HINMAN, Steven J. RICHARDS
  • Glucocorticoid receptor ligands for the treatment of metabolic disorders
    Patent number: 7521439
    Abstract: This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: April 21, 2009
    Assignee: Karo Bio AB
    Inventors: Richard D. Bishop, Russell Drew Cink, Bradley D. Gates, Lars T. Hagberg, Peer B. Jacobsen, Philip R. Kym, Chunqiu Lai, Marvin Robert Leanna, James T. Link, Steven J. Richards, Noah Tu, Tom W. von Geldern
  • Glucocorticoid receptor ligands for the treatment of metabolic disorders
    Patent number: 7141559
    Abstract: This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.
    Type: Grant
    Filed: June 12, 2003
    Date of Patent: November 28, 2006
    Assignee: Karo Bio AB
    Inventors: Richard D. Bishop, Russell Drew Cink, Bradley D. Gates, Lars T. Hagberg, Peer B. Jacobsen, Philip R. Kym, Chunqiu Lai, Marvin Robert Leanna, James T. Link, Steven J. Richards, Noah Tu, Tom W. von Geldern
  • Novel glucocorticoid receptor ligands for the treatment of metabolic disorders
    Publication number: 20040235810
    Abstract: This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.
    Type: Application
    Filed: June 12, 2003
    Publication date: November 25, 2004
    Inventors: Richard D. Bishop, Russell Drew Cink, Bradley D. Gates, Lars T. Hagberg, Peer B. Jacobson, Philip R. Kym, Chunqui Lai, Marvin Robert Leanna, James T. Link, Steven J. Richards, Noah Tu, Tom W. von Geldern