Patents by Inventor Steven J. Rothstein

Steven J. Rothstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Compositions for Effecting Developmental Gene Expression in Plants
    Publication number: 20140173779
    Abstract: The invention provides nucleotide sequences that can be used in operable association with a promoter to express a polynucleotide sequence of interest in a plant, plant part or plant cell at particular stages of development and/or in specific tissues. and methods for directing developmental stage specific and/or tissue specific expression of a polynucleotide of interest.
    Type: Application
    Filed: April 5, 2013
    Publication date: June 19, 2014
    Applicants: The University of Guelph, Syngenta Participations AG
    Inventors: Christophe Liseron-Monfils, Manish N. Raizada, Joseph Colasanti, Gregory Downs, Yong-Mei Bi, Lewis N. Lukens, Steven J. Rothstein, Tong Zhu, Xi Chen
  • Transgenic maize seed and method for controlling insect pests
    Patent number: 6720488
    Abstract: DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: April 13, 2004
    Assignee: Syngenta Investment Corporation
    Inventors: Michael Koziel, Nalini Desai, Gary M. Pace, Jan Suttie, Nadine Carozzi, Cindy Boyce, John L. Dawson, Erik Dunder, Martha Wright, Karen Launis, Steven J. Rothstein, Kelly Lewis, Gregory Warren, Steve Evola
  • Method of producing transgenic maize using direct transformation of commercially important genotypes
    Publication number: 20030237117
    Abstract: Methods for transformation of maize with nucleic acid sequences of interest are disclosed. The method involves subjecting immature zygotic embryos or Type I callus to high velocity microprojectile bombardment. The method is capable of producing transformed maize lines of commercial importance and their hybrid combinations.
    Type: Application
    Filed: April 30, 2002
    Publication date: December 25, 2003
    Inventors: Michael Koziel, Nalini Desai, Kelly Lewis, Vance Kramer, Gregory Warren, Steve Evola, Lyle D. Crossland, Martha Wright, Ellis Merlin, Karen Launis, Steven J. Rothstein, Cindy Bowman, John L. Dawson, Erik Dunder, Gary M. Pace, Jan Suttie, Nadine Carozzi, Annick De Framond, James O. Linder, Robert L. Miller, Bruce W. Skillings, Alan W. Mousel, Albert R. Hornbrook, Christopher P. Clucas, Moez R. Meghji, Andreas H. Tanner, Francis E. Cassagne, Gilles Pollini, Terry Ray Colbert, Francis P. Cammack
  • Synthetic DNA sequence having enhanced insecticidal activity in maize
    Publication number: 20030046726
    Abstract: DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
    Type: Application
    Filed: November 20, 2001
    Publication date: March 6, 2003
    Inventors: Michael Koziel, Nalini Desai, Kelly Lewis, Gregory Warren, Steve Evola, Martha Wright, Karen Launis, Steven J. Rothstein, Cindy Boyce, John L. Dawson, Erik Dunder, Gary M. Pace, Jan Suttie, Nadine Carozzi
  • Method of producing transgenic maize using direct transformation of commercially important genotypes
    Patent number: 6403865
    Abstract: Methods for transformation of maize with nucleic acid sequences of interest are disclosed. The method involves subjecting immature zygotic embryos or Type I callus to high velocity microprojectile bombardment. The method is capable of producing transformed maize lines of commercial importance and their hybrid combinations.
    Type: Grant
    Filed: May 10, 1995
    Date of Patent: June 11, 2002
    Assignee: Syngenta Investment Corp.
    Inventors: Michael G. Koziel, Nalini M. Desai, Kelly S. Lewis, Vance C. Kramer, Gregory W. Warren, Stephen V. Evola, Lyle D. Crossland, Martha S. Wright, Ellis J. Merlin, Karen L. Launis, Steven J. Rothstein, Cindy G. Bowman, John L. Dawson, Erik M. Dunder, Gary M. Pace, Janet L. Suttie, Nadine Carozzi, Annick De Framond, James O. Linder, Robert L. Miller, Bruce W. Skillings, Alan W. Mousel, Albert R. Hornbrook, Christopher P. Clucas, Moez Rajabali Meghji, Andreas H. Tanner, Francis E. Cassagne, Gilles Pollini, Terry Ray Colbert, Francis P. Cammack
  • Synthetic DNA sequences having enhanced insecticidal activity in maize
    Patent number: 6320100
    Abstract: DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
    Type: Grant
    Filed: April 11, 2000
    Date of Patent: November 20, 2001
    Assignee: Syngenta Investments, Inc.
    Inventors: Michael G. Koziel, Nalini M. Desai, Kelly S. Lewis, Gregory W. Warren, Stephen V. Evola, Martha S. Wright, Karen L. Launis, Steven J. Rothstein, Cindy G. Bowman, John L. Dawson, Erik M. Dunder, Gary M. Pace, Janet L. Suttie
  • Synthetic DNA sequence having enhanced insecticidal activity in maize
    Patent number: 6075185
    Abstract: DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: June 13, 2000
    Assignee: Novartis Finance Corporation
    Inventors: Michael G. Koziel, Nalini M. Desai, Kelly S. Lewis, Gregory W. Warren, Stephen V. Evola, Martha S. Wright, Karen L. Launis, Steven J. Rothstein, Cindy G. Bowman, John L. Dawson, Erik M. Dunder, Gary M. Pace, Janet L. Suttie
  • Nucleic acid promoter fragment isolated from a plant tryptophan synthase alpha subunit (trpA) gene
    Patent number: 6018104
    Abstract: DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: January 25, 2000
    Assignee: Novartis Finance Corporation
    Inventors: Michael G. Koziel, Nalini M. Desai, Kelly S. Lewis, Vance C. Kramer, Gregory W. Warren, Stephen V. Evola, Martha S. Wright, Karen L. Launis, Steven J. Rothstein, Cindy G. Bowman, John L. Dawson, Erik M. Dunder, Gary M. Pace, Janet L. Suttie
  • Self-aligning peptides modeled on human elastin and other fibrous proteins
    Patent number: 5969106
    Abstract: A polypeptide is provided that has a secondary structure characterized by at least three beta-sheet/beta-turn structures, and that is not a naturally occurring fibrous protein. Such polypeptides, illustrated by one modeled on elastin, are useful in prosthesis.
    Type: Grant
    Filed: August 7, 1997
    Date of Patent: October 19, 1999
    Assignees: The Hospital for Sick Children, Protein Specialties, Ltd.
    Inventors: Aser Rothstein, Fred W. Keely, Steven J. Rothstein
  • S-locus receptor kinase gene in a self-incompatible brassica napus line
    Patent number: 5821094
    Abstract: The S-locus of Brassica contains the genetic information that encodes for self-incompatibility. In its first aspect, it is directed to an isolated gene, the SRK-910 gene, that segregates with the self-incompatibility phenotype. In its second aspect, the present invention is directed to an isolated cDNA that corresponds to the isolated gene and that has 2749 nucleotides.The isolated cDNA of the present invention encodes for a protein, i.e., the S-locus receptor kinase-910 protein ("the SRK-910 protein") which is also a part of the present invention. The SRK-910 protein, has 858 amino acids and is encoded for by the first 2575 nucleotides of the isolated cDNA of the present invention.The present invention is also directed to an oligonucleotide probe that is capable of distinguishing the SRK-910 gene from partially homologous genes at the S-locus that encode for the S-locus glycoproteins.
    Type: Grant
    Filed: June 24, 1994
    Date of Patent: October 13, 1998
    Assignee: University of Guelph
    Inventors: Steven J. Rothstein, Daphne R. Goring
  • Synthetic DNA sequence having enhanced insecticidal activity in maize
    Patent number: 5625136
    Abstract: DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
    Type: Grant
    Filed: September 25, 1992
    Date of Patent: April 29, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Michael G. Koziel, Nalini M. Desai, Kelly S. Lewis, Vance C. Kramer, Gregory W. Warren, Stephen V. Evola, Lyle D. Crossland, Martha S. Wright, Ellis J. Merlin, Karen L. Launis, Steven J. Rothstein, Cindy G. Bowman, John L. Dawson, Erik M. Dunder, Gary M. Pace, Janet L. Suttie
  • Cloning of complementary DNA encoding maize nitrite reductase
    Patent number: 4997930
    Abstract: Maize cDNA coding for nitrite reductase is cloned, using a spinach nitrite reductase cDNA as a heterologous probe, and is characterized. A method is provided to use the cloned maize nitrite reductase cDNA to determine the number of nitrite reductase genes per maize genome and to study nitrite reductase mRNA regulation in maize.
    Type: Grant
    Filed: March 16, 1989
    Date of Patent: March 5, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Kristine N. Lahners, Steven J. Rothstein