Patents by Inventor Steven J. Siegel

Steven J. Siegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Implants for the treatment of dopamine associated states
    Patent number: 10278916
    Abstract: Biodegradable implants comprising dopamine modulating compounds are described.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: May 7, 2019
    Assignees: NuPathe Inc., The Trustees of the University of Pennsylvania
    Inventors: Terri B. Sebree, Steven J. Siegel
  • IMPLANTS FOR THE TREATMENT OF DOPAMINE ASSOCIATED STATES
    Publication number: 20150328376
    Abstract: Biodegradable implants comprising dopamine modulating compounds are described.
    Type: Application
    Filed: December 18, 2014
    Publication date: November 19, 2015
    Inventors: Terri B. Sebree, Steven J. Siegel
  • METHODS FOR TREATING PARKINSON'S DISEASE
    Publication number: 20150313897
    Abstract: Methods for restoring normal patterns of activity in a subject suffering from Parkinson's Disease are disclosed that include administering an effective steady state concentration of a dopamine modulating compound continuously for a prolonged period of time such that normal patterns of activity are substantially restored in the subject.
    Type: Application
    Filed: April 2, 2015
    Publication date: November 5, 2015
    Inventors: Terri B. Sebree, Steven J. Siegel
  • IMPLANTS FOR THE TREATMENT OF DOPAMINE ASSOCIATED STATES
    Publication number: 20140221451
    Abstract: Biodegradable implants comprising dopamine modulating compounds are described.
    Type: Application
    Filed: February 7, 2014
    Publication date: August 7, 2014
    Applicants: The Trustees of the University of Pennsylvania, NuPathe, Inc.
    Inventors: Terri B. Sebree, Steven J. Siegel
  • METHODS FOR TREATING PARKINSON'S DISEASE
    Publication number: 20140178449
    Abstract: Methods for restoring normal patterns of activity in a subject suffering from Parkinson's Disease are disclosed that include administering an effective steady state concentration of a dopamine modulating compound continuously for a prolonged period of time such that normal patterns of activity are substantially restored in the subject.
    Type: Application
    Filed: October 30, 2013
    Publication date: June 26, 2014
    Applicant: NuPathe, Inc.
    Inventors: Terri B. Sebree, Steven J. Siegel
  • Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use
    Patent number: 8758795
    Abstract: Surgically implantable drug delivery systems for long-term delivery of haloperidol containing a biodegradable polymer and haloperidol fabricated into the surgically implantable drug delivery systems via solvent casting and compression molding are provided. Also provided are methods for producing the surgically implantable drug delivery systems and methods for using these systems in the treatment of psychotic disorders such as schizophrenia.
    Type: Grant
    Filed: October 20, 2009
    Date of Patent: June 24, 2014
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Steven J. Siegel, Karen I. Winey, Raquel E. Gur, Robert H. Lenox
  • RNase a peptides, fragments and uses thereof
    Patent number: 8748572
    Abstract: The present invention features isolated polypeptides that have bactericidal and angiogenic activities. The invention features isolated polypeptides comprising amino acid sequences of RNase A ribonucleases, fragments and variants thereof, pharmaceutical compositions, and methods for treatment of a subject.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: June 10, 2014
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Takeaki Nitto, Kimberly D. Dyer, Meggan Czapiga, Helene F. Rosenberg, Steven J. Siegel
  • IMPLANTS FOR THE TREATMENT OF DOPAMINE ASSOCIATED STATES
    Publication number: 20140147486
    Abstract: Biodegradable implants comprising dopamine modulating compounds are described.
    Type: Application
    Filed: June 6, 2013
    Publication date: May 29, 2014
    Inventors: Terri B. Sebree, Steven J. Siegel
  • Implants for the treatment of dopamine associated states
    Patent number: 8475829
    Abstract: Biodegradable implants comprising dopamine modulating compounds are described.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: July 2, 2013
    Assignees: NuPathe Inc., The Trustees of the University of Pennsylvania
    Inventors: Terri B. Sebree, Steven J. Siegel
  • Implants for the treatment of dopamine associated states
    Patent number: 8475830
    Abstract: Biodegradable implants comprising dopamine modulating compounds are described.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: July 2, 2013
    Assignees: NuPathe Inc., The Trustees of the University of Pennsylvania
    Inventors: Terri B. Sebree, Steven J. Siegel
  • Methods For Treating Parkinson's Disease
    Publication number: 20110159066
    Abstract: Methods for restoring normal patterns of activity in a subject suffering from Parkinson's Disease are disclosed that include administering an effective steady state concentration of a dopamine modulating compound continuously for a prolonged period of time such that normal patterns of activity are substantially restored in the subject.
    Type: Application
    Filed: November 2, 2010
    Publication date: June 30, 2011
    Inventors: Terri B. Sebree, Steven J. Siegel
  • RNASE A PEPTIDES, FRAGMENTS AND USES THEREOF
    Publication number: 20100305025
    Abstract: The present invention features isolated polypeptides that have bactericidal and angiogenic activities. The invention features isolated polypeptides comprising amino acid sequences of RNase A ribonucleases, fragments and variants thereof, pharmaceutical compositions, and methods for treatment of a subject.
    Type: Application
    Filed: August 24, 2007
    Publication date: December 2, 2010
    Applicant: Government of the US, as represented by the Secretary, Department of Health and Human Services
    Inventors: Takeaki Nitto, Kimberly D. Dyer, Meggan Czapiga, Helene F. Rosenberg, Steven J. Siegel
  • POLYMER-BASED SURGICALLY IMPLANTABLE HALOPERIDOL DELIVERY SYSTEMS AND METHODS FOR THEIR PRODUCTION AND USE
    Publication number: 20100104618
    Abstract: Surgically implantable drug delivery systems for long-term delivery of haloperidol containing a biodegradable polymer and haloperidol fabricated into the surgically implantable drug delivery systems via solvent casting and compression molding are provided. Also provided are methods for producing the surgically implantable drug delivery systems and methods for using these systems in the treatment of psychotic disorders such as schizophrenia.
    Type: Application
    Filed: October 20, 2009
    Publication date: April 29, 2010
    Inventors: Steven J. SIEGEL, Karen I. Winey, Raquel E. Gur, Robert H. Lenox
  • Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use
    Patent number: 7666445
    Abstract: Surgically implantable drug delivery systems for long-term delivery of haloperidol containing a biodegradable polymer and haloperidol fabricated into the surgically implantable drug delivery systems via solvent casting and compression molding are provided. Also provided are methods for producing the surgically implantable drug delivery systems and methods for using these systems in the treatment of psychotic disorders such as schizophrenia.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: February 23, 2010
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Steven J. Siegel, Karen I. Winey, Raquel E. Gur, Robert H. Lenox
  • Implants for the treatment of dopamine associated states
    Publication number: 20080152693
    Abstract: Biodegradable implants comprising dopamine modulating compounds are described.
    Type: Application
    Filed: February 29, 2008
    Publication date: June 26, 2008
    Applicant: NuPathe Inc.
    Inventors: Terri B. Sebree, Steven J. Siegel
  • Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use
    Publication number: 20020179096
    Abstract: Surgically implantable drug delivery systems for long-term delivery of haloperidol containing a biodegradable polymer and haloperidol fabricated into the surgically implantable drug delivery systems via solvent casting and compression molding are provided. Also provided are methods for producing the surgically implantable drug delivery systems and methods for using these systems in the treatment of psychotic disorders such as schizophrenia.
    Type: Application
    Filed: October 19, 2001
    Publication date: December 5, 2002
    Inventors: Steven J. Siegel, Karen I. Winey, Raquel E. Gur, Robert H. Lenox