Patents by Inventor Steven James Green

Steven James Green has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AHR AGONISTS
    Publication number: 20230159493
    Abstract: The present invention relates to certain substituted AHR agonist compounds, to pharmaceutical compositions comprising the compounds and to methods of using the compounds to treat immune-mediated diseases.
    Type: Application
    Filed: September 13, 2022
    Publication date: May 25, 2023
    Inventors: Lacie Marie CHAUVIGNE-HINES, Christian Alexander CLARKE, Douglas Linn GERNERT, Steven James GREEN, Brian Morgan WATSON
  • AHR AGONISTS
    Publication number: 20230127797
    Abstract: The present invention relates to certain substituted AHR agonist compounds, to pharmaceutical compositions comprising the compounds and to methods of using the compounds to treat immune-mediated diseases.
    Type: Application
    Filed: September 13, 2022
    Publication date: April 27, 2023
    Inventors: Cheryl Ann CARSON, Christian Alexander CLARKE, Douglas Linn GERNERT, Steven James GREEN, William Glen HOLLOWAY
  • AMINOTHIAZINIES AND THEIR USE AS BACE1 INHIBITORS
    Publication number: 20210355138
    Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treatment of neurodegenerative diseases and disorders, such as Alzheimer's disease.
    Type: Application
    Filed: August 2, 2017
    Publication date: November 18, 2021
    Inventor: Steven James GREEN
  • 1,4-Oxazines useful as selective BACE1 inhibitors
    Patent number: 10399995
    Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, useful as a BACE1 inhibitor.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: September 3, 2019
    Assignee: Eli Lilly and Company
    Inventors: Steven James Green, Erik James Hembre, II, Dustin James Mergott
  • 1,4-OXAZINES USEFUL AS SELECTIVE BACE1 INHIBITORS
    Publication number: 20190161502
    Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, useful as a BACE1 inhibitor.
    Type: Application
    Filed: August 18, 2017
    Publication date: May 30, 2019
    Inventors: Steven James Green, Erik James Hembre, II, Dustin James Mergott
  • BACE inhibitors
    Patent number: 9169271
    Abstract: The present invention provides a compound of Formula III: wherein A is: and Z, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: October 27, 2015
    Assignee: Eli Lilly and Company
    Inventors: Steven James Green, Erik James Hembre, Dustin James Mergott, Yuan Shi, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • BACE INHIBITORS
    Publication number: 20150210716
    Abstract: The present invention provides a compound of Formula III: wherein A is: and Z, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 2, 2015
    Publication date: July 30, 2015
    Inventors: Steven James GREEN, Erik James HEMBRE, Dustin James MERGOTT, Yuan SHI, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20150157641
    Abstract: The present invention provides a compound of Formula I: wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 19, 2015
    Publication date: June 11, 2015
    Inventors: Steven James GREEN, Dustin James MERGOTT, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • BACE inhibitors
    Patent number: 9029367
    Abstract: The present invention provides a compound of Formula III: Formula III wherein A is: and Z, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof, which is useful for treating Alzheimer's disease.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: May 12, 2015
    Assignee: Eli Lilly and Company
    Inventors: Steven James Green, Erik James Hembre, Dustin James Mergott, Yuan Shi, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • Tetrahydropyrrolothiazine compounds
    Patent number: 8987254
    Abstract: The present invention provides a compound of Formula I: wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: March 24, 2015
    Assignee: Eli Lilly and Company
    Inventors: Steven James Green, Dustin James Mergott, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • BACE INHIBITORS
    Publication number: 20140371212
    Abstract: The present invention provides a compound of Formula III: wherein A is: and Z, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 11, 2014
    Publication date: December 18, 2014
    Inventors: Steven James GREEN, Erik James HEMBRE, Dustin James MERGOTT, Yuan SHI, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20140350245
    Abstract: The present invention provides a compound of Formula I: wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 7, 2014
    Publication date: November 27, 2014
    Inventors: Steven James GREEN, Dustin James MERGOTT, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • Tetrahydropyrrolothiazine compounds
    Patent number: 8889856
    Abstract: The present invention provides compounds of Formula I: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: November 18, 2014
    Assignee: Eli Lilly and Company
    Inventors: James Peter Beck, Steven James Green, Jose Eduardo Lopez, Brian Michael Mathes, Dustin James Mergott, Warren Jaye Porter, Zoran Rankovic, Yuan Shi, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • Tetrahydropyrrolothiazine compounds
    Patent number: 8841293
    Abstract: The present invention provides a compound of Formula I: Formula I wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: September 23, 2014
    Assignee: Eli Lilly and Company
    Inventors: Steven James Green, Dustin James Mergott, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20140275044
    Abstract: The present invention provides a compound of Formula I: wherein R is H or F; and A is: or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 4, 2014
    Publication date: September 18, 2014
    Applicant: Eli Lilly and Company
    Inventors: Steven James GREEN, Dustin James MERGOTT, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20140256933
    Abstract: The present invention provides compounds of Formula I: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 22, 2014
    Publication date: September 11, 2014
    Applicant: Eli Lilly and Company
    Inventors: James Peter BECK, Steven James GREEN, Jose Eduardo LOPEZ, Brian Michael MATHES, Dustin James MERGOTT, Warren Jaye PORTER, Zoran RANKOVIC, Yuan SHI, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • Tetrahydropyrrolothiazine compounds
    Patent number: 8772282
    Abstract: The present invention provides compounds of Formula I: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: July 8, 2014
    Assignee: Eli Lilly and Company
    Inventors: James Peter Beck, Steven James Green, Jose Eduardo Lopez, Brian Michael Mathes, Dustin James Mergott, Warren Jaye Porter, Zoran Rankovic, Yuan Shi, Brian Morgan Watson, Leonard Larry Winneroski, Jr.
  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20140094454
    Abstract: The present invention provides compounds of Formula I: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 4, 2013
    Publication date: April 3, 2014
    Applicant: Eli Lilly and Company
    Inventors: James Peter BECK, Steven James GREEN, Jose Eduardo LOPEZ, Brian Michael MATHES, Dustin James MERGOTT, Warren Jaye PORTER, Zoran RANKOVIC, Yuan SHI, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR.
  • TETRAHYDROPYRROLOTHIAZINE COMPOUNDS
    Publication number: 20130261111
    Abstract: The present invention provides compounds of Formula I: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 27, 2013
    Publication date: October 3, 2013
    Applicant: Eli Lilly and Company
    Inventors: James Peter BECK, Steven James GREEN, Jose Eduardo LOPEZ, Brian Michael MATHES, Dustin James MERGOTT, Warren Jaye PORTER, Zoran RANKOVIC, Yuan SHI, Brian Morgan WATSON, Leonard Larry WINNEROSKI, JR
  • NOVEL MCH RECEPTOR ANTAGONISTS
    Publication number: 20120302547
    Abstract: The present invention relates to a melanin concentrating hormone antagonist compound of formula (I) wherein R1, Ra, Rb, R2, L1, R3, R4 and R5 are as defined, or a pharmaceutically acceptable salt, enantiomer, diastereomer or mixture of diasteromers thereof useful in the treatment, obesity and related diseases.
    Type: Application
    Filed: August 8, 2012
    Publication date: November 29, 2012
    Applicant: ELI LILLY AND COMPANY
    Inventors: Macklin Brian Arnold, Yen Dao, Kevin Matthew Gardinier, David Joseph Garmene, Steven James Green, Erik James Hembre, Jianliang Lu