Abstract: The present invention provides a secondary cooling apparatus and method of providing cooling to one or more features in a refrigerator. In one exemplary aspect of the present invention, the refrigerator includes a cabinet having a door, a first cooling loop in the cabinet, and a second cooling loop cooled by the first cooling loop. The secondary cooling loop is adapted to cool the one or more features in the cabinet or on the door of the refrigerator. In another exemplary aspect of the present invention, a method for providing cooling in a refrigerator to one or more features in a compartment or on a door of the refrigerator includes providing a first cooling loop within a refrigerator, cooling a secondary cooling loop directly or indirectly with the first cooling loop, and transferring cooling from the secondary cooling loop to the one or more features in the compartment or on the door of the refrigerator.

Abstract: Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.

Abstract: A method and apparatus for decoding the LTE physical broadcast channel (PBCH). The transmissions are made by an evolved NodeB (eNB). At least one template symbol sequence representative of a potential transmission by the eNB over the PBCH is provided. A signal or signals transmitted over the PBCH by the eNB is received, the signal or signals indicative of a received symbol sequence. Correlation operations are performed for correlating the at least one template symbol sequence against the received symbol sequence. A representative symbol sequence, timing parameter, or both, is selected, based on the correlation operations. The representative symbol sequence is indicative of information transmitted by the eNB over the LTE PBCH. The timing parameter is indicative of timing of said information transmitted by the eNB.

Abstract: The invention provides a compound for use as a protein kinase B inhibitor, the compound being a compound of the formula (I) or salts, solvates, tautomers or N-oxides thereof, wherein T is N or CR5; J1-J2 is N?C(R6), (R7)C?N, (R8)N—C(O), (R8)2C—C(O), N?N or (R7)C?C(R6); E is a monocyclic carbocyclic or heterocyclic group of 5 or 6 ring members, the heterocyclic group containing up to 3 heteroatoms selected from O, N and S; Q1 is a bond or a saturated C1-3 hydrocarbon linker group, one of the carbon atoms in the linker group being optionally be replaced by an oxygen or nitrogen atom, or an adjacent pair of carbon atoms may be replaced by CONRq or NRqCO where Rq is hydrogen or methyl, or Rq is a C1-4 alkylene chain linked to R or a carbon atom of Q1 to form a cyclic moiety; and wherein the carbon atoms of the linker group Q1 may optionally bear one or more substituents selected from fluorine and hydroxy; Q2 is a bond or a saturated hydrocarbon linker group containing from 1 to 3 carbon atoms, wherein one of the

Abstract: This disclosure relates generally to methods and devices for use in viewing and positioning an eye with a gonio lens system, such as during ocular exams and ocular surgeries. Some embodiments of the gonio lens system can include a gonio lens for viewing one or more tissues and structures of the eye. In addition, the gonio lens system can include one or more positioning features for controlling movement positioning of the eye.

Abstract: A tile-based graphics system has a rendering space sub-divided into a plurality of tiles which are to be processed. Graphics data items, such as parameters or texels, are fetched into a cache for use in processing one of the tiles. Indicators are determined for the graphics data items, whereby the indicator for a graphics data item indicates the number of tiles with which that graphics data item is associated. The graphics data items are evicted from the cache in accordance with the indicators of the graphics data items. For example, the indicator for a graphics data item may be a count of the number of tiles with which that graphics data item is associated, whereby the graphics data item(s) with the lowest count(s) is (are) evicted from the cache.

Abstract: The present technology provides a method and system for monetizing the usage of a certain “reserved service,” which comprises usage of certain reserved wireless operating modes, such as Ultra High Coverage Mode (UHCM), usage of one or more reserved Modulation and Coding Schemes (MCSs), or a combination thereof. In some embodiments the reserved MCSs may be employed solely when using the reserved operating mode. Similarly, the reserved operating mode may be defined at least in part by its usage of the reserved MCSs.

Abstract: The invention relates to new quinoline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract: A container (22) includes an oxygen-sensitive beverage, for example a vitamin C-containing beverage. A closure (40) seals the mouth (28) of container (22). The closure includes an oxygen scavenging structure, for example a closure, which comprises a hydrogen generating means and a catalyst for catalysing a reaction between hydrogen and oxygen.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: wherein the variables are as defined herein.

Abstract: The invention provides a device for the detection and mapping of radiation, the device comprising a polymeric core (18) located within an external shell material (1), wherein the polymeric core comprises a plurality of stacked polymeric sheets comprising at least one radiation sensitive component which is sensitive to said radiation emitted by said radioactive materials and the external sheath comprises a collimation sheath (1). Preferably, the polymeric core comprises a cubic, cylindrical, spherical or truncated spherical shape which is encased within the external shell. The external shell is preferably comprised of a metal, most preferably tungsten.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; solid forms of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I-1: wherein the variables are as defined herein. Additionally, the compounds of this invention have formula II: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined herein.

Abstract: The present invention relates to pyrrolopyrazines compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: wherein the variables are as defined herein.

Abstract: A mask for delivery of respiratory therapy to a patient may include one or more of the following improvements: rigidizer provided to headgear strap, locking clip/clip receptacle headgear connection, keyed headgear buckles, lotion dispenser on frame, rotatable prongs to adjust orientation, alignment indicators provided to prong, cushion and/or frame, chin flap with bellows arrangement, vent holes positioned away from gas entry port, and vent holes to direct washout gas at an angle.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: wherein the variables are as defined herein.

Abstract: Aspects relate to arbitrating access to an interconnect among multiple ports. For example, input ports receive requests for access to identified destination ports and buffer these in one or more FIFOs. A picker associated with respective FIFO(s) begins an empty arbitration packet that includes a location for each output port and fills one or more locations in the packet, such as based on a prioritization scheme. Each packet is passed in a ring to another picker, which performs a fill that does not conflict with previously filled locations in that packet. Each picker has an opportunity to place requests in each of the packets. Results of the arbitration are dispatched to reorder buffers associated with respective output ports and used to schedule the interconnect. Each arbitration cycle thus produces a set of control information for an interconnect to be used in subsequent data transfer steps.

Abstract: A method for specifying the layout of computing system resources includes receiving a request for a virtual machine, the request comprising a processor requirement and a memory requirement, gathering resource groupings, each resource grouping comprising a latency penalty between a processor and at least a memory. The method further includes calculating a proportionality for each resource grouping, wherein the proportionality comprises a minimum of: an amount of the processor requirement the resource grouping can satisfy and an amount of the memory requirement the resource grouping can satisfy, sorting the resource groupings based on at least the proportionality for each resource grouping to create an ordered list and binding, based on the ordered list, at least one resource group to the virtual machine, wherein the at least one resource group satisfies the processor requirement and the memory requirement.

Abstract: Disclosed herein is a system and method for optimizing a developer's ability to find and navigate relevant documents, relationships, and other information related to an identifier in the code they are developing. An inline viewport is presented to the user in response to the user selecting an identifier in the code whereby the user is able to see relevant information related to the identifier in a spatially consistent location with the code they are investigating. The developer further has the ability to cascade the viewports such that multiple levels of depth of relationships can be viewed in the viewport.

Abstract: Disclosed herein is a system and method for optimizing a developer's ability to find and navigate relevant documents, relationships, and other information related to an identifier in the code they are developing. An inline viewport is presented to the user in response to the user selecting an identifier in the code whereby the user is able to see relevant information related to the identifier in a spatially consistent location with the code they are investigating. Further, the developer has the ability to make changes to the code in the viewport without leaving the current editor.

Abstract: Disclosed herein is a system and method for optimizing a developer's ability to find and navigate relevant documents, relationships, and other information related to an identifier in the code they are developing. An inline viewport is presented to the user in response to the user selecting an identifier in the code whereby the user is able to see relevant information related to the identifier in a spatially consistent location with the code they are investigating. Further, the developer has the ability to make changes to the code in the viewport without leaving the current editor.