Patents by Inventor Steven K. Spaderna

Steven K. Spaderna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040002120
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: March 7, 2002
    Publication date: January 1, 2004
    Inventors: Ramesh Kekuda, Velizar T. Tchernev, Xiaohong Liu, Kimberly A. Spytek, Meera Patturajan, Catherine E. Burgess, Corine A.M. Vernet, Li Li, Linda Gorman, Uriel M. Malyankar, Ferenc L. Boldog, Xiaojia (Sasha) Guo, Suresh G. Shenoy, Muralidhara Padigaru, Raymond J. Taupier, Charles E. Miller, Stacie J. Casman, Carol E. A. Pena, Esha A. Gangolli, Vladimir Y. Gusev, Glennda Smithson, Bryan D. Zerhusen, Valerie Gerlach, Pascale F-J Pochart, Elma R. Fernandes, Richard A. Shimkets, Luca Rastelli, Steven K. Spaderna, William J. LaRochelle, Mei Zhong, Nikolai V. Khramtsov, Edward Z. Voss, John L. Herrmann
  • Novel polypeptides and nucleic acids encoding same
    Publication number: 20030216308
    Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: June 17, 2002
    Publication date: November 20, 2003
    Inventors: David W. Anderson, Xiaojia (Sasha) Guo, Vladimir Y. Gusev, John L. Herrmann, Li Li, Peter S. Mezes, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Luca Rastelli, Richard A. Shimkets, Glennda Smithson, Steven K. Spaderna, Raymond J. Taupier, Corine A.M. Vernet
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030216545
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 27, 2001
    Publication date: November 20, 2003
    Inventors: Kimberly A. Spytek, Stacie Casman, Muralidhara Padigaru, Kevin S. Dickson, Corine Vernet, Steven K. Spaderna, Suresh G. Shenoy, Valerie Gerlach, Karen Ellerman, Shlomit Edinger, John R. MacDougall, Glennda Smithson, Li Li, Uriel M. Malyankar, Sarah Taylor, Erik Gunther, Velizar T. Tchernev
  • Proteins and nucleic acids encoding same
    Publication number: 20030215449
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: March 15, 2002
    Publication date: November 20, 2003
    Inventors: Peter D. Mezes, Luca Rastelli, John L. Herrmann, John R. MacDougall, Haihong Zhong, Stacie J. Casman, Ferenc L. Boldog, Richard A. Shimkets, Linda Gorman, Andrew J. Eisen, Steven K. Spaderna, Corine A.M. Vernet, Constance Berghs, Kimberly A. Spytek, Vincent A. DiPippo, Bryan D. Zerhusen, John A. Peyman, Karen Ellerman, David J. Stone, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Shlomit R. Edinger, Edward Z. Voss, Charles E. Miller
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030207394
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 3, 2002
    Publication date: November 6, 2003
    Inventors: John P. Alsobrook, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, William M. Grosse, Vladimir Y. Gusev, Weizhen Ji, Denise M. Lepley, Xiaohong Liu, Amanda J. Mezick, Muralidhara Padigaru, Meera Patturajan, Luca Rastelli, Lei Shen, Suresh G. Shenoy, Richard A. Shimkets, Steven K. Spaderna, Kimberly A. Spytek, Edward S. Szekeres, Raymond J. Taupier, Velizar T. Tchernev, Bryan D. Zerhusen, Edward Z. Voss
  • Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
    Publication number: 20030208039
    Abstract: Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.
    Type: Application
    Filed: March 8, 2002
    Publication date: November 6, 2003
    Inventors: Muralidhara Padigaru, Suresh G. Shenoy, Remesh Kekuda, Vladimir Gusev, Pascale F-J Pochart, Mei Zhong, Luca Rastelli, Peter D. Mezes, Glennda Smithson, Xiaojia Sasha Guo, Valerie Gerlach, Stacie J. Casman, Ferenc L. Boldog, Li Li, Bryan D. Zerhusen, Velizar T. Tchernev, Esha A. Gangolli, Corine A.M. Vernet, Carol E. A. Pena, Catherine E. Burgess, Xiaohong Liu, Kimberly A. Spytek, Linda Gorman, Steven K. Spaderna, Edward Z. Voss, Uriel M. Malyankar, David W. Anderson, Meera Patturajan, Charles E. Miller, Raymond J. Taupier
  • Novel polypeptides and nucleic acids encoding same
    Publication number: 20030199465
    Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: April 22, 2002
    Publication date: October 23, 2003
    Inventors: Uriel M. Malyankar, Velizar T. Tchernev, Muralidhara Padigaru, Raymond J. Taupier, Kimberly A. Spytek, Xiaojia (Sasha) Guo, Steven K. Spaderna, Ferenc L. Boldog, Valerie Gerlach, Karen Ellerman, John R. MacDougall, Glennda Smithson
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030198953
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: May 23, 2001
    Publication date: October 23, 2003
    Inventors: Kimberly A. Spytek, Kumud Majumder, Velizar T. Tchernev, Vishnu Mishra, Muralidhara Padigaru, Steven K. Spaderna, Suresh G. Shenoy, Luca Rastelli, Li Li, Raymond J. Taupier, Esha Gangolli
  • Novel polypeptides and nucleic acids encoding same
    Publication number: 20030148485
    Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: March 20, 2001
    Publication date: August 7, 2003
    Inventors: Raymond J. Taupier, Kumud Majumder, Steven K. Spaderna, Glennda Smithson, Peter S. Mezes, Corine A.M. Vernet
  • Novel human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20030139358
    Abstract: The invention provides polypeptides, designated herein as POLYX polypeptides, as well as polynucleotides encoding POLYX polypeptides, and antibodies that immunospecifically-bind to POLYX polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the POLYX polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.
    Type: Application
    Filed: May 4, 2001
    Publication date: July 24, 2003
    Inventors: Kimberly A. Spytek, Muralidhara Padigaru, Kumud Majumder, John R. MacDougall, David J. Stone, Esha A. Gangolli, Steven K. Spaderna, Glennda Smithson
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030096952
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: March 29, 2001
    Publication date: May 22, 2003
    Inventors: Kumud Majumder, Steven K. Spaderna, Raymond J. Taupier, Muralidhara Padigaru, Catherine Burgess, Richard A. Shimkets, Kimberly A. Spytek, Xiaohong Liu, Meera Patturajan, Vladimir Y. Gusev
  • Novel serine/threonine protein-kinase like proteins and nucleic acids encoding the same
    Publication number: 20030077697
    Abstract: The present invention provides a novel isolated SER5 polynucleotide and a polypeptide encoded by the SER5 polynucleotide. Also provided are the antibodies that immunospecifically bind to a SER5 polypeptide or any derivative, variant, mutant or fragment of the SER5 polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SER5 polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states as well as other uses.
    Type: Application
    Filed: July 3, 2001
    Publication date: April 24, 2003
    Inventors: Valerie L. Gerlach, John R. MacDougall, Kerry E. Quinn, Kumud Majumder, Kimberly A. Spytek, Corine Vernet, Catherine E. Burgess, Elma R. Fernandes, Luca Rastelli, John L. Herrmann, Steven K. Spaderna, Richard A. Shimkets, Raymond J. Taupier
  • Novel polypeptides and nucleic acids encoding same
    Publication number: 20030064489
    Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: March 12, 2001
    Publication date: April 3, 2003
    Inventors: Li Li, Muralidhara Padigaru, Corine A.M. Vernet, Elma R. Fernandes, Richard A. Shimkets, Steven K. Spaderna, Kumud Majumder
  • Novel polypeptides and nucleic acids encoding same
    Publication number: 20030059768
    Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: February 23, 2001
    Publication date: March 27, 2003
    Inventors: Corine Vernet, Elma Fernandes, Richard A. Shimkets, John MacDougall, Steven K. Spaderna
  • Aortic carboxypeptidase-like protein and nucleic acids encoding same
    Publication number: 20030032166
    Abstract: Disclosed are nucleic acids encoding aortic carboxypeptidase-related polypeptides, polypeptides encoded by these nucleic acids, and methods of using these nucleic acids and polypeptides.
    Type: Application
    Filed: November 28, 2001
    Publication date: February 13, 2003
    Inventors: Kerry E. Quinn, Carol E. A. Pena, Li Li, Steven K. Spaderna, Mario W. Leite
  • Polypeptides and nucleic acids encoding same
    Publication number: 20020077466
    Abstract: The present invention provides novel isolated MEMX polynucleotides and polypeptides encoded by the MEMX polynucleotides. Also provided are the antibodies that immunospecifically bind to a MEMX polypeptide or any derivative, variant, mutant or fragment of the MEMX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the MEMX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: December 14, 2000
    Publication date: June 20, 2002
    Inventors: Steven K. Spaderna, Kerry E. Quinn, Richard A. Shimkets, Muralidhara Padigaru, Kimberly A. Spytek