Patents by Inventor Steven L. MATHIEU

Steven L. MATHIEU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRIMIDINE COMPOUNDS AND METHODS USING THE SAME
    Publication number: 20210363154
    Abstract: The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits that include the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disorder hi a subject. For example, the disorder is a neurodegenerative disease.
    Type: Application
    Filed: March 29, 2021
    Publication date: November 25, 2021
    Inventors: Gregory D. CUNY, Marcie A. GLICKSMAN, Steven L. MATHIEU, Yukari Y. PERRELLA, Vincent DARMENCY, Hrvoje LUSIC, Kevin J. HODGETTS
  • Pyrimidine compounds and methods using the same
    Patent number: 10961254
    Abstract: The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits that include the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disorder in a subject. For example, the disorder is a neurodegenerative disease.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: March 30, 2021
    Assignees: Yuma Therapeutics, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Gregory D. Cuny, Marcie A. Glicksman, Kevin J. Hodgetts, Steven L. Mathieu, Yukari Y. Perrella, Vincent Darmency, Hrvoje Lusic
  • PYRIMIDINE COMPOUNDS AND METHODS USING THE SAME
    Publication number: 20190389878
    Abstract: The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits that include the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disorder in a subject. For example, the disorder is a neurodegenerative disease.
    Type: Application
    Filed: July 1, 2019
    Publication date: December 26, 2019
    Inventors: Gregory D. CUNY, Marcie A. GLICKSMAN, Kevin J. HODGETTS, Steven L. MATHIEU, Yukari Y. PERRELLA, Vincent DARMENCY, Hrvoje LUSIC
  • Pyrimidine compounds and methods using the same
    Patent number: 10336768
    Abstract: The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits that include the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disorder in a subject. For example, the disorder is a neurodegenerative disease.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: July 2, 2019
    Assignees: Yuma Therapeutics, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Gregory D. Cuny, Marcie A. Glicksman, Kevin J. Hodgetts, Steven L. Mathieu, Yukari Y. Perrella, Vincent Darmency, Hrvoje Lusic
  • PYRIMIDINE COMPOUNDS AND METHODS USING THE SAME
    Publication number: 20170107228
    Abstract: The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits that include the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disorder in a subject. For example, the disorder is a neurodegenerative disease.
    Type: Application
    Filed: June 15, 2015
    Publication date: April 20, 2017
    Inventors: Gregory D. CUNY, Marcie A. GLICKSMAN, Kevin J. HODGETTS, Steven L. MATHIEU, Yukari Y. PERRELLA, Vincent DARMENCY, Hrvoje LUSIC