Abstract: One embodiment can provide a method and system for implementing flow control. During operation, a switch identifies a command from a host to access a storage device coupled to the switch. The switch queues the command in a command queue corresponding to the host. In response to determining that an amount of data pending transmission to the host from the storage device is below a predetermined threshold, the switch removes a command from the command queue and forwards the removed command to the storage device.

Abstract: One embodiment can provide a method and system for implementing flow control. During operation, a switch identifies a command from a host to access a storage device coupled to the switch. The switch queues the command in a command queue corresponding to the host. In response to determining that an amount of data pending transmission to the host from the storage device is below a predetermined threshold, the switch removes a command from the command queue and forwards the removed command to the storage device.

Abstract: Various embodiments for implementing a switched direct attached shared storage architecture as disclosed herein include: providing a plurality of compute nodes, each compute node having integrated compute capabilities, data storage, and a network interface controller (Host NIC), the plurality of compute nodes being in data communication with each other via a local area network, the plurality of compute nodes each including distributed storage processing software resident thereon; providing a plurality of physical data storage devices in data communication with a storage controller; and enabling data communications in a data store switch fabric between the plurality of compute nodes and the plurality of physical data storage devices via the Host NIC and the storage controller, the data store switch fabric encapsulating data requests from the plurality of compute nodes into data frames for transport to corresponding physical data storage devices.

Abstract: Various embodiments for implementing a switched direct attached shared storage architecture as disclosed herein include: providing a plurality of compute nodes, each compute node having integrated compute capabilities, data storage, and a network interface controller (Host NIC), the plurality of compute nodes being in data communication with each other via a local area network, the plurality of compute nodes each including distributed storage processing software resident thereon; providing a plurality of physical data storage devices in data communication with a storage controller; and enabling data communications in a data store switch fabric between the plurality of compute nodes and the plurality of physical data storage devices via the Host NIC and the storage controller, the data store switch fabric encapsulating data requests from the plurality of compute nodes into data frames for transport to corresponding physical data storage devices.

Abstract: This invention describes a method for removing unreacted activated lipid moieties using a bifunctional ligand containing a first functional group reactive with the activating group of the lipid and a second functional group capable of binding to an affinity reagent or support. These reagents can be used to quench reactions between peptides/proteins and other moieties such as activated PEGs or lipids. Once the reaction has been quenched, the reaction mixture can be passed over an affinity column that will bind the peptide, biotin or other ligand attached to the “quenched” reagent and thereby remove it from the reaction mixture.