Patents by Inventor Steven Lance BERNSTEIN

Steven Lance BERNSTEIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING EYE DISEASES USING OPTIC NERVE LAMINA REGION NEURAL PROGENITOR CELL-DERIVED SECRETED EXTRACELLULAR VESICLES AND FREE PROTEINS
    Publication number: 20260144825
    Abstract: Soluble proteins and extracellular vesicles (EVs) produced by optic nerve lamina region neural progenitor cells (ONLR-NPCs) are provided. Such proteins and EVs include growth factors and survival factors that can be used in the treatment of optic nerve diseases, such as glaucoma. Also provided are methods of treating or preventing optic nerve diseases, such as glaucoma, using ONLR-NPC-based compositions.
    Type: Application
    Filed: October 16, 2023
    Publication date: May 28, 2026
    Applicant: University of Maryland, Baltimore
    Inventor: Steven Lance BERNSTEIN
  • Methods of treating optic nerve diseases using neural progenitor cell growth factors
    Patent number: 12213996
    Abstract: Optic nerve lamina region neural progenitor cells (ONLR-NPCs) are provided. Such cells secrete growth factors and survival factors that can be used in the treatment of optic nerve diseases, such as glaucoma. Also provided are methods of treating or preventing optic nerve diseases, such as glaucoma, using one or more factors secreted by ONLR-NPCs, combinations of factors secreted by ONLR-NPCs, or culture media conditioned by ONLR-NPCs.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: February 4, 2025
    Assignees: UNIVERSITY OF MARYLAND, BALTIMORE, REGENERATIVE RESEARCH FOUNDATION
    Inventors: Steven Lance Bernstein, Candace L. Kerr, Sally Temple Stern
  • METHODS OF TREATING OPTIC NERVE DISEASES USING NEURAL PROGENITOR CELL GROWTH FACTORS
    Publication number: 20220175844
    Abstract: Optic nerve lamina region neural progenitor cells (ONLR-NPCs) are provided. Such cells secrete growth factors and survival factors that can be used in the treatment of optic nerve diseases, such as glaucoma. Also provided are methods of treating or preventing optic nerve diseases, such as glaucoma, using one or more factors secreted by ONLR-NPCs, combinations of factors secreted by ONLR-NPCs, or culture media conditioned by ONLR-NPCs.
    Type: Application
    Filed: February 1, 2019
    Publication date: June 9, 2022
    Applicants: University of Maryland, Baltimore, REGENERATIVE RESEARCH FOUNDATION
    Inventors: Steven Lance BERNSTEIN, Candace L. KERR, Sally TEMPLE STERN