Abstract: A container device with an outer shell that has an opening that is sealed by a closure mechanism. The closure mechanism may include resealable closure elements that are configured to partially or wholly seal the opening. In some examples, the closure elements may be magnetic strips. In addition, the closure mechanism may include curved members to prevent the opening from closing when the closure mechanism is in an open configuration.

Abstract: An example bag may include a first sidewall, a second sidewall, a top wall, and a bottom wall. The bottom wall may include an outer layer, and the bottom wall may be secured to the first sidewall and the second sidewall by wrapping a fabric forming the first sidewall and the second sidewall over sections of the outer layer. The bag may further include a closure and a pair of straps. The first sidewall and the second sidewall may include endcaps having a first layered structure, the first layered structure may include a compression molded outer layer and an additional structural layer formed of a first foam material, and the endcaps may be more rigid than the first sidewall, the second sidewall, and the top wall. The bottom wall may include a second layered structure formed of a second foam material positioned on the outer layer, and the bottom wall may be more rigid than the first sidewall, the second sidewall, and the top wall.

Abstract: An insulating container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching devices, in the closed configuration. In some examples, the insulating container further includes a pull handle assembly with a telescopic three-stage arm configuration defined by a stowed configuration, a partially extended configuration, and a fully extended configuration. In other examples, the insulating container further includes a wheel assembly with a pair of wheels mounted with one or two axles, and further including a wheel grommet for absorbing shock and cushioning the axle.

Abstract: An insulating device including an outer shell, an inner liner forming a storage compartment, an insulating layer positioned in between the outer shell and the inner liner, wherein the insulating layer provides insulation for the storage compartment, and an opening configured to allow access to the storage compartment.

Abstract: A container device with an outer shell that has an opening that is sealed by a closure mechanism. The closure mechanism may include resealable closure elements that are configured to partially or wholly seal the opening. In some examples, the closure elements may be magnetic strips. In addition, the closure mechanism may include curved members to prevent the opening from closing when the closure mechanism is in an open configuration.

Abstract: An insulating container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching devices, in the closed configuration. In some examples, the insulating container further includes a pull handle assembly with a telescopic three-stage arm configuration defined by a stowed configuration, a partially extended configuration, and a fully extended configuration. In other examples, the insulating container further includes a wheel assembly with a pair of wheels mounted with one or two axles, and further including a wheel grommet for absorbing shock and cushioning the axle. In still other examples, the insulating container further includes a drain plug assembly on the rear sidewall adjacent to the bottom portion of the base, the drain plug assembly comprising a main tube that cooperatively engages with an outer tube with a plurality of ratchet teeth that engage one or more ratchet keys on the main tube.

Abstract: Various embodiments are disclosed for providing machine learning routines with peripheral device data to infer driver activity and location. Peripheral device data may be collected on a peripheral device having a machine learning routine executing thereon to infer driver activity and perform improved estimation of driver location. Using driver activity and location estimation, contextually relevant delivery workflow assistance may be automatically provided to a delivery driver or other individual without requiring manual input, thereby improving driver safety and operational efficiency.

Abstract: A closure having a first flange with first engagement mechanism and a second with a second engagement mechanism disposed between the first end and the second end. The first engagement mechanism configured to engage the second engagement mechanism. A slider configured to selectively engage the first engagement mechanism and the second mechanism when moved in a first direction and disengage the first engagement mechanism from the second engagement mechanism when moved in a second direction. The closure is substantially watertight in the closed position.

Abstract: An example bag may include an outer shell comprising a front panel, a rear panel, a top sidewall, a bottom sidewall, a first sidewall, a second sidewall forming, and a closure configured to move from an open position to a closed position. The bag may also include a pair of adjustable straps. The adjustable straps can be configured to move from a first backpack carry position to a second hand carry position by releasing the adjustable straps from the outer shell of the bag from the first carry position and securing the adjustable straps to the second carry position.

Abstract: The present disclosure relates generally to immunoglobulin-related compositions (e.g., multi-specific antibodies or antigen binding fragments thereof) that can bind to the GPA33 protein. The multi-specific antibodies of the present technology are useful in methods for detecting and treating a GPA33-associated cancer in a subject in need thereof.

Abstract: Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.