Patents by Inventor Steven M. Hutchins

Steven M. Hutchins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combinatorial synthesis on soluble polyvalent supports having a discrete architecture
    Patent number: 6132953
    Abstract: The present invention is directed to the use of a soluble polyvalent support for the preparation of combinatorial libraries of compounds. The resultant combinatorial libraries are useful in screening for biologically active moieties in the drug discovery process or in developing compounds with desired physical and chemical properties.
    Type: Grant
    Filed: June 30, 1997
    Date of Patent: October 17, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Kevin T. Chapman, Steven M. Hutchins, Ronald M. Kim, Mahua Manna
  • Substituted carbamoyl and oxycarbonyl derivatives of biphenylmethylamines
    Patent number: 5312820
    Abstract: Carbamoyl and oxycarbonyl derivatives of biphenylmethylamines of structure I are angiotensin-II antagonists with balanced AT.sub.1 and AT.sub.2 activity useful in the treatment of hypertension and related disorders and ocular hypertension. ##STR1## where X is --O-- or --N(R.sup.7)--.
    Type: Grant
    Filed: July 17, 1992
    Date of Patent: May 17, 1994
    Assignee: Merck & Co., Inc.
    Inventors: Wallace T. Ashton, Linda L. Chang, William J. Greenlee, Steven M. Hutchins, Ralph A. Rivero
  • Substituted pyrazoles, compositions and use
    Patent number: 5262412
    Abstract: Substituted pyrazole compounds are angiotensin II antagonists and therefore useful in the treatment of hypertension, and related cardiovascular disorders and ocular hypertension.
    Type: Grant
    Filed: March 10, 1993
    Date of Patent: November 16, 1993
    Assignee: Merck & Co., Inc.
    Inventors: Wallace T. Ashton, Linda L. Chang, William J. Greenlee, Steven M. Hutchins
  • Angiotensin II antagonists incorporating a substituted imidazo [1,2-b][1,2,4]triazole
    Patent number: 5187179
    Abstract: There are disclosed substituted imidazo[1,2-b][1,2,4]triazole derivatives of Formula I which are useful as angiotensin II antagonists.
    Type: Grant
    Filed: March 22, 1991
    Date of Patent: February 16, 1993
    Assignee: Merck & Co., Inc.
    Inventors: Wallace T. Ashton, Steven M. Hutchins, Malcolm MacCoss