Patents by Inventor Steven M. Jay

Steven M. Jay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR CARDIOPROTECTION AND CARDIOREGENERATION WITH DIMERS OF EGF FAMILY LIGANDS
    Publication number: 20150343023
    Abstract: The invention provides methods and compositions for reducing, preventing or reversing cardio toxicity side effects associated with certain therapeutic agents. The invention also provides methods and compositions for treating heart dysfunction including heart failure, and for reversing the effects of myocardial infarction. The various aspects of the invention involve the use of ligand dimers, such as neuregulin dimers, that selectively induce the dimerization of certain EGF receptors in cardiac tissue.
    Type: Application
    Filed: May 11, 2015
    Publication date: December 3, 2015
    Applicants: The Brigham and Women's Hospital, Inc., Massachusetts Institute of Technology
    Inventors: Steven M. Jay, Linda G. Griffith, Richard T. Lee
  • Methods for cardioprotection and cardioregeneration with dimers of EGF family ligands
    Patent number: 9029328
    Abstract: The invention provides methods and compositions for reducing, preventing or reversing cardio toxicity side effects associated with certain therapeutic agents. The invention also provides methods and compositions for treating heart dysfunction including heart failure, and for reversing the effects of myocardial infarction. The various aspects of the invention involve the use of ligand dimers, such as neuregulin dimers, that selectively induce the dimerization of certain EGF receptors in cardiac tissue.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: May 12, 2015
    Assignees: The Brigham and Women's Hospital, Inc., Massachusetts Institute of Technology
    Inventors: Steven M. Jay, Linda G. Griffith, Richard T. Lee
  • METHODS AND COMPOSITIONS FOR CARDIOPROTECTION AND CARDIOREGENERATION
    Publication number: 20130196911
    Abstract: The invention provides methods and compositions for reducing, preventing or reversing cardio toxicity side effects associated with certain therapeutic agents. The invention also provides methods and compositions for treating heart dysfunction including heart failure, and for reversing the effects of myocardial infarction. The various aspects of the invention involve the use of ligand dimers, such as neuregulin dimers, that selectively induce the dimerization of certain EGF receptors in cardiac tissue.
    Type: Application
    Filed: March 24, 2011
    Publication date: August 1, 2013
    Applicants: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Steven M. Jay, Linda G. Griffith, Richard T. Lee