Abstract: Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated human p53. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.

Abstract: Stun grenades may include a fuze configured to ignite a delay material secured to a housing including a delay chamber in which the delay material is located. A handle of the fuze may be located over a final payload chamber of the series of payload chambers, payload material in the final payload chamber being configured to ignite after ignition of payload material in each other payload chamber of a series of payload chambers. Methods of assembling stun grenades may involve positioning an obstruction in a port extending between a delay chamber and a payload chamber of a series of payload chambers surrounding the delay chamber in a housing. A delay material may be packed in the delay chamber. The obstruction may be removed, and a payload material may be positioned in the payload chamber and the port.

Abstract: Retention clips for safety mechanisms of illumination flares include an abutment surface configured for abutment of an end of a rigid sleeve coupled to an igniter initiation cable and one or more protrusions configured to extend at least partially over a lateral side surface of the rigid sleeve when the rigid sleeve is retained by the clip. Safety mechanisms, illumination flares, and methods for igniting illumination flares involve such retention clips.

Abstract: Retention clips for safety mechanisms of illumination flares include an abutment surface configured for abutment of an end of a rigid sleeve coupled to an igniter initiation cable and one or more protrusions configured to extend at least partially over a lateral side surface of the rigid sleeve when the rigid sleeve is retained by the clip. Safety mechanisms, illumination flares, and methods for igniting illumination flares involve such retention clips.

Abstract: Stun grenades may include a fuze configured to ignite a delay material secured to a housing including a delay chamber in which the delay material is located. A handle of the fuze may be located over a final payload chamber of the series of payload chambers, payload material in the final payload chamber being configured to ignite after ignition of payload material in each other payload chamber of a series of payload chambers. Methods of assembling stun grenades may involve positioning an obstruction in a port extending between a delay chamber and a payload chamber of a series of payload chambers surrounding the delay chamber in a housing. A delay material may be packed in the delay chamber. The obstruction may be removed, and a payload material may be positioned in the payload chamber and the port.

Abstract: Gas-generating devices with grain-retention structures and related methods and systems are described. In particular, gas-generating devices having at least one retention structure fixed to a frame and positioned between adjacent gas-generant grains arranged in a longitudinal stack. Fire suppression systems comprising such gas-generating devices are also described. Additionally, methods of manufacturing gas-generating devices, as well as methods of generating a gas and methods of suppressing a fire utilizing such gas-generating devices are described.

Abstract: Gas-generating devices with grain-retention structures and related methods and systems are described. In particular, gas-generating devices having at least one retention structure fixed to a frame and positioned between adjacent gas-generant grains arranged in a longitudinal stack. Fire suppression systems comprising such gas-generating devices are also described. Additionally, methods of manufacturing gas-generating devices, as well as methods of generating a gas and methods of suppressing a fire utilizing such gas-generating devices are described.