Patents by Inventor Steven M. Vicik

Steven M. Vicik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Separation methods
    Patent number: 7855280
    Abstract: Separation methods, for example, to isolate a recombinant protein, are disclosed. In some implementations, a method includes forming a solid containing a first cation and a first anion in a medium containing a protein, and separating the solid from the protein.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: December 21, 2010
    Assignee: Wyeth LLC
    Inventors: Jonathan L. Coffman, Russell I. Shpritzer, Steven M. Vicik
  • Methods of refolding proteins
    Patent number: 6632635
    Abstract: Methods are disclosed for refolding proteins of the TGF-&bgr; family of proteins. The methods employ as refolding agents one or more compounds which are acid substituted aminocyclohexanes.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: October 14, 2003
    Assignee: Genetics Institute
    Inventor: Steven M. Vicik
  • Methods of refolding proteins
    Patent number: 6596511
    Abstract: Methods are disclosed for refolding proteins of the TGF-&bgr; family of proteins. The methods employ as refolding agents one or more compounds which are non-detergent zwitterionic compounds, such as sulfobetaines, substituted pyridines, substituted pyrroles and acid substituted aminocyclohexanes.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: July 22, 2003
    Assignee: Genetics Institute LLC
    Inventor: Steven M. Vicik
  • Methods of refolding proteins
    Patent number: 6593106
    Abstract: Methods are disclosed for refolding proteins of the TGF-&bgr; family of proteins. The methods employ as refolding agents one or more compounds which are non-detergent zwitterionic compounds, such as sulfobetaines, substituted pyridines, substituted pyrroles and acid substituted aminocyclohexanes.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: July 15, 2003
    Assignee: Genetics Institute LLC
    Inventor: Steven M. Vicik
  • Methods of refolding proteins
    Patent number: 6593107
    Abstract: Methods are disclosed for refolding proteins of the TGF-&bgr; family of proteins. The methods employ as refolding agents one or more compounds which are substituted pyridines.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: July 15, 2003
    Assignee: Genetics Institute LLC
    Inventor: Steven M. Vicik
  • METHODS OF REFOLDING PROTEINS
    Publication number: 20020052026
    Abstract: Methods are disclosed for refolding proteins of the TGF-&bgr; family of proteins. The methods employ as refolding agents one or more compounds which are non-detergent zwitterionic compounds, such as sulfobetaines, substituted pyridines, substituted pyrroles and acid substituted aminocyclohexanes.
    Type: Application
    Filed: October 8, 1997
    Publication date: May 2, 2002
    Inventor: STEVEN M. VICIK
  • Protein recovery & purification methods
    Patent number: 5760189
    Abstract: Provided by the present invention are novel methods of protein recovery and purification methods and more specifically novel methods for the recovery and purification thioredoxin fusion proteins, especially of IL-11.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: June 2, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Steven M. Vicik, Neil L. Schauer, James R. Mercer, Edward R. LaVallie, Catherine A. Briasco, Jeffrey S. Deetz, Dwight Winters, Jenifer L. Thomas