Patents by Inventor Steven McIntosh

Steven McIntosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240092818
    Abstract: The present invention relates to efficient synthetic processes useful in the preparation of antiviral nucleosides, particularly uridine 4-oxime 5?-(2-methylpropanoate) {(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl]oxolan-2-yl}methyl 2-methylpropanoate and pharmaceutically acceptable salts, derivatives, tautomers, isomers, and prodrugs of, which may be active as antiviral agents, as well as compositions and methods thereof. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.
    Type: Application
    Filed: December 17, 2021
    Publication date: March 21, 2024
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Tamas Benkovics, Patrick S. Fier, Anna Fryszkowska, Mark A. Huffman, Tetsuji Itoh, Jongrock Kong, Peter E. Maligres, Kevin M. Maloney, John McIntosh, Grant S. Murphy, Steven M. Silverman, Hao Yang
  • Publication number: 20170335309
    Abstract: Novel semiconductor nanoparticles and methods of biosynthesizing the same are provided by biosynthetic processes using cell-free supernatants and isolated enzymes.
    Type: Application
    Filed: May 19, 2016
    Publication date: November 23, 2017
    Applicant: Lehigh University
    Inventors: Bryan Berger, Steven McIntosh
  • Publication number: 20160265001
    Abstract: New semiconductor nanoparticles and manufacturing technologies, including novel methods, systems, and compositions, are provided herein. Robust, reproducible production of large amounts of semiconductor nanoparticles, such as quantum dots, from bacterial cultures during continuous growth is provided, without a need for extensive post growth processing or modification. The result is a novel semiconductor of nanoparticle dimensions and quality that is suitable for commercial applications in lighting, display, imaging, diagnostics, photovoltaics and hydrogen generation, for example. In one embodiment, bacterial-based synthesis methods for producing nanocrystal semiconductor quantum dots are provided by aqueous, environmentally friendly media and methods.
    Type: Application
    Filed: March 21, 2016
    Publication date: September 15, 2016
    Inventors: Bryan Berger, Steven McIntosh
  • Patent number: 9293717
    Abstract: New semiconductor nanoparticles and manufacturing technologies, including novel methods, systems, and compositions, are provided herein. Robust, reproducible production of large amounts of semiconductor nanoparticles, such as quantum dots, from bacterial cultures during continuous growth is provided, without a need for extensive post growth processing or modification. The result is a novel semiconductor of nanoparticle dimensions and quality that is suitable for commercial applications in lighting, display, imaging, diagnostics, photovoltaics and hydrogen generation, for example. In one embodiment, bacterial-based synthesis methods for producing nanocrystal semiconductor quantum dots are provided by aqueous, environmentally friendly media and methods.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: March 22, 2016
    Assignee: Lehigh University
    Inventors: Bryan Berger, Steven McIntosh
  • Publication number: 20140287483
    Abstract: New semiconductor nanoparticles and manufacturing technologies, including novel methods, systems, and compositions, are provided herein. Robust, reproducible production of large amounts of semiconductor nanoparticles, such as quantum dots, from bacterial cultures during continuous growth is provided, without a need for extensive post growth processing or modification. The result is a novel semiconductor of nanoparticle dimensions and quality that is suitable for commercial applications in lighting, display, imaging, diagnostics, photovoltaics and hydrogen generation, for example. In one embodiment, bacterial-based synthesis methods for producing nanocrystal semiconductor quantum dots are provided by aqueous, environmentally friendly media and methods.
    Type: Application
    Filed: August 16, 2012
    Publication date: September 25, 2014
    Applicant: LEHIGH UNIVERSITY
    Inventors: Bryan Berger, Steven McIntosh