Patents by Inventor Steven Mentzer

Steven Mentzer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating inflammatory disorders using regulators of microvessel dilations
    Publication number: 20060211604
    Abstract: The invention relates to methods for treating inflammatory diseases. Methods for analyzing microcirculation structural changes are also provided.
    Type: Application
    Filed: November 28, 2005
    Publication date: September 21, 2006
    Applicant: The Brigham and Women's Hospital, Inc.
    Inventor: Steven Mentzer
  • Molecular database for antibody characterization
    Patent number: 7058658
    Abstract: The invention relates to a cumulative, evolving molecular database of monospecific probes and their characteristics. In particular, the invention relates to a computer repository of histograms based upon quantitative flow cytometry. The invention further relates to a system containing a database of monospecific probe properties, the database connected to users through a network to allow users to enter selection criteria and retrieve monospecific probe properties. The invention further relates to a data set useful to refine existing analytic algorithms. The refinement of these algorithms enables computer searches for relationships between known and unknown monospecific probes. Thus, the invention also provides for searching in the database to identify relationships between monospecific probes, groups of probes, and their targets.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: June 6, 2006
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventor: Steven Mentzer
  • Compounds or agents that inhibit and induce the formation of focal microvessel dilatations
    Publication number: 20050142066
    Abstract: The invention relates to the discovery that inflammation involves a structural modification to the microvascular architecture that results in the formation of focal microvessel dilatations or “microangiectasias.” The focal microvessel dilatations cause localized slowing of blood cell flow velocity that promotes the accumulation of extravascular lymphocytes. Methods are disclosed herein that exploit this discovery to screen for compounds that modulate the accumulation of extravascular lymphocytes. In addition, methods for treating patients suffering from cancer and diseases or pathologies associated with lymphocytic infiltration are disclosed.
    Type: Application
    Filed: December 2, 2004
    Publication date: June 30, 2005
    Inventor: Steven Mentzer
  • Molecular database for antibody characterization
    Publication number: 20010049689
    Abstract: The invention relates to a cumulative, evolving molecular database of monospecific probes and their characteristics. In particular, the invention relates to a computer repository of histograms based upon quantitative flow cytometry. The invention further relates to a system containing a database of monospecific probe properties, the database connected to users through a network to allow users to enter selection criteria and retrieve monospecific probe properties. The invention further relates to a data set useful to refine existing analytic algorithms. The refinement of these algorithms enables computer searches for relationships between known and unknown monospecific probes. Thus, the invention also provides for searching in the database to identify relationships between monospecific probes, groups of probes, and their targets.
    Type: Application
    Filed: March 28, 2001
    Publication date: December 6, 2001
    Inventor: Steven Mentzer