Patents by Inventor Steven Michael Opal

Steven Michael Opal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical product for the treatment of sepsis
    Patent number: 6315999
    Abstract: An antibody to tumor necrosis factor-&agr; (anti-TNF) and an antibody to bacterial lipopolysaccharide (anti-LPS) used together in a neutropenic rat model of sepsis are shown to enhance survival of the rats relative to either antibody used alone. Pharmaceutical products including each of the components are therefore of utility in therapy of sepsis. The anti-LPS antibody included may be specific for the O-specific clain of a particular bacterial lipopolysaccharide (serotype specific antibody) but preferably recognizes the core glycolipid of lipopolysaccharide.
    Type: Grant
    Filed: June 2, 1994
    Date of Patent: November 13, 2001
    Assignee: Solvay, S.A.
    Inventors: Jerald C. Sadoff, Steven Michael Opal, Alan S. Cross, Mark William Bodmer