Patents by Inventor Steven N. Fiering

Steven N. Fiering has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing human monoclonal immunoglobuling antibodies
    Patent number: 9944692
    Abstract: The present invention a method for producing a human immunoglobulin G (IgG) antibody using a prime-boost regime in a Bone Marrow Liver Thymic (BLT) mouse.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: April 17, 2018
    Assignee: Trustees of Dartmouth College
    Inventors: William G. North, Steven N. Fiering
  • Method for treating cancer with vaccine
    Patent number: 9757440
    Abstract: The present invention provides attenuated Toxoplasma gondii mutants for use as vaccines in the prevention or treatment of cancer.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: September 12, 2017
    Assignee: Trustees of Dartmouth College
    Inventors: David J. Bzik, Barbara A. Fox, Steven N. Fiering, Jose R. Conejo-Garcia, Jason Baird
  • Magnetic particle imaging (MPI) system and method for use of iron-based nanoparticles in imaging and diagnosis
    Patent number: 8954131
    Abstract: A method for diagnosing certain types of cancers provides a nanoparticle agent to be uptaken by cancer cells for diagnosis and treatment of certain cancers. A compound containing nanoparticles is directed toward a tumor site, and then a predetermined time period passes to allow the nanoparticles to be uptaken by the cancer cells. Imaging is then performed on the nanoparticles by an appropriate imaging device to determine the concentration of nanoparticles uptaken by the cancer cells. Finally, image data provided by the imaging device is analyzed to determine the concentration of nanoparticles and thereby determine whether a tumor is present. The nanoparticle agent can further be employed as a treatment of certain cancers. After the uptake of nanoparticles into the cells, a predetermined field applied to the nanoparticles for a sufficient period of time activates the magnetic cores of the nanoparticles to include hyperthermia-mediated destruction of the cancer cells.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: February 10, 2015
    Assignee: The Trustees of Dartmouth College
    Inventors: John B. Weaver, Jose R. Conejo-Garcia, Steven N. Fiering, Adam M. Rauwerdink, Uciane K. Scarlett
  • METHOD FOR PRODUCING HUMAN MONOCLONAL IMMUNOGLOBULIN G ANTIBODIES
    Publication number: 20140329312
    Abstract: The present invention a method for producing a human immunoglobulin G (IgG) antibody using a prime-boost regime in a Bone Marrow Liver Thymic (BLT) mouse.
    Type: Application
    Filed: November 26, 2012
    Publication date: November 6, 2014
    Inventors: William G. North, Steven N. Fiering
  • Method for Treating Cancer with Toxoplasma Gondii Vaccine
    Publication number: 20120045477
    Abstract: The present invention provides attenuated Toxoplasma gondii mutants for use as vaccines in the prevention or treatment of cancer.
    Type: Application
    Filed: October 19, 2011
    Publication date: February 23, 2012
    Applicant: Trustees of Dartmouth College
    Inventors: David J. Bzik, Barbara A. Fox, Steven N. Fiering, Jose R. Conejo-Garcia, Jason Baird
  • SYSTEM AND METHOD FOR USE OF NANOPARTICLES IN IMAGING AND DIAGNOSIS
    Publication number: 20110098558
    Abstract: A method for diagnosing certain types of cancers provides a nanoparticle agent to be uptaken by cancer cells for diagnosis and treatment of certain cancers. A compound containing nanoparticles is directed toward a tumor site, and then a predetermined time period passes to allow the nanoparticles to be uptaken by the cancer cells. Imaging is then performed on the nanoparticles by an appropriate imaging device to determine the concentration of nanoparticles uptaken by the cancer cells. Finally, image data provided by the imaging device is analyzed to determine the concentration of nanoparticles and thereby determine whether a tumor is present. The nanoparticle agent can further be employed as a treatment of certain cancers. After the uptake of nanoparticles into the cells, a predetermined field applied to the nanoparticles for a sufficient period of time activates the magnetic cores of the nanoparticles to include hyperthermia-mediated destruction of the cancer cells.
    Type: Application
    Filed: October 26, 2010
    Publication date: April 28, 2011
    Applicant: DARTMOUTH COLLEGE, THE TRUSTEES OF
    Inventors: John B. Weaver, Jose R. Conejo-Garcia, Steven N. Fiering, Adam M. Rauwerdink, Uciane K. Scarlett