Patents by Inventor Steven N. Quayle

Steven N. Quayle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HDAC inhibitors, alone or in combination with BTK inhibitors, for treating chronic lymphocytic leukemia
    Patent number: 11813261
    Abstract: Disclosed are histone deacetylase (HDAC) inhibitors, or combinations comprising an HDAC inhibitor and a Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of chronic lymphocytic leukemia in a subject in need thereof. Also provided herein are methods for treating chronic lymphocytic leukemia in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an HDAC inhibitor, or a combination comprising an HDAC inhibitor and a BTK inhibitor. Other related methods are disclosed.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: November 14, 2023
    Assignees: ACETYLON PHARMACEUTICALS, INC., H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
    Inventors: Simon S. Jones, Steven N. Quayle, Eva Sahakian, Javier Pinilla Ibarz
  • HDAC INHIBITORS, ALONE OR IN COMBINATION WITH BTK INHIBITORS, FOR TREATING CHRONIC LYMPHOCYTIC LEUKEMIA
    Publication number: 20190209559
    Abstract: Disclosed are histone deacetylase (HDAC) inhibitors, or combinations comprising an HDAC inhibitor and a Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of chronic lymphocytic leukemia in a subject in need thereof. Also provided herein are methods for treating chronic lymphocytic leukemia in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an HDAC inhibitor, or a combination comprising an HDAC inhibitor and a BTK inhibitor. Other related methods are disclosed.
    Type: Application
    Filed: April 19, 2017
    Publication date: July 11, 2019
    Inventors: Simon S. Jones, Steven N. Quayle, Eva Sahakian, Javier Pinilla Ibarz