Abstract: The invention provides nucleic acids and polypeptides for enhanced expression of nucleic acids and proteins. In one aspect, the sequences serve as transcription and translation enhancers or stabilizers, and can be incorporated in expression constructs at or near the translation control elements. The invention provides methods of producing mRNA (transcripts) and proteins. The invention provides methods of discovering new enhancer elements.

Abstract: The present invention provides promoters from plants capable of driving gene expression in plant cells. The promoters vary in strength and in tissue specificity, and can be used to facilitate the development of transgenic plants in which tissue preferred expression, constitutive expression, and the strength of transgene expression is either more or less critical.

Abstract: The invention provides compositions and in vitro and ex vivo methods for de-differentiating or re-programming mammalian cells. In alternative embodiments, the invention provides compositions comprising mixtures of Designed Regulatory Proteins (DRPs) or Reprogramming DRP protein (ReD) for de-differentiating or re-programming mammalian cells. The invention also provides compositions and methods for direct reprogramming of a first differentiated phenotype of a cell to a second differentiated phenotype.

Abstract: The present invention provides promoters from plants capable of driving gene expression in plant cells. The promoters vary in strength and in tissue specificity, and can be used to facilitate the development of transgenic plants in which tissue preferred expression, constitutive expression, and the strength of transgene expression is either more or less critical.

Abstract: A molecular classification procedure based on activity levels of modules in protein networks, wherein the proteins are biomarkers for chronic lymphocytic leukemia (CLL), and method for use of the subnetworks to distinguish between patients at low or high risk of progression of their disease.

Abstract: The invention provides compositions (e.g., pharmaceuticals, formulations) and methods for ameliorating (e.g., preventing or treating) an anemia and/or stimulating erythropoiesis and/or EPO erythropoietin synthesis. The invention provides compositions comprising a chimeric protein artificial transcription factor comprising a plurality of (multiple) protein DNA-binding domains, e.g., zinc finger binding domains, specific for the promoter region of an erythropoietin (EPO) gene; a consensus nuclear localization protein sequence; a cell-penetrating peptide sequence; and a transcription activation domain.

Abstract: The invention provides nucleic acids and polypeptides for enhanced expression of nucleic acids and proteins. In one aspect, the sequences serve as transcription and translation enhancers or stabilizers, and can be incorporated in expression constructs at or near the translation control elements. The invention provides methods of producing mRNA (transcripts) and proteins. The invention provides methods of discovering new enhancer elements.

Abstract: Abiotic stress responsive polynucleotides and polypeptides are disclosed. Also disclosed are vectors, expression cassettes, host cells, and plants containing such polynucleotides. Also provided are methods for using such polynucleotides and polypeptides, for example, to alter the responsiveness of a plant to abiotic stress.

Abstract: The invention relates to methods of producing plants with increased resistance to pathogen infection by expressing disease resistance genes in the plants and transgenic plants having enhanced pathogen resistance.

Abstract: The invention relates to the genetic modification of plants, particularly to the expression of P-glycoprotein genes in transformed plants. Nucleotide sequences for the Br2 gene encoding a P-glycoprotein of maize and methods for their use are provided. The sequences find use in modifying the growth of plants.

Abstract: The present invention provides promoters from plants capable of driving gene expression in plant cells. The promoters vary in strength and in tissue specificity, and can be used to facilitate the development of transgenic plants in which tissue preferred expression, constitutive expression, and the strength of transgene expression is either more or less critical.

Abstract: The present invention provides promoters from plants capable of driving gene expression in plant cells. The promoters vary in strength and in tissue specificity, and can be used to facilitate the development of transgenic plants in which tissue preferred expression, constitutive expression, and the strength of transgene expression is either more or less critical.

Abstract: The invention relates to the genetic modification of plants, particularly to the expression of P-glycoprotein genes in transformed plants. Nucleotide sequences for the Br2 gene encoding a P-glycoprotein of maize and methods for their use are provided. The sequences find use in modifying the growth of plants.

Abstract: The present invention relates to the use of a variety of methods for generating functional thioredoxin reductase variants in which at least one physical, chemical or biological property of the variant is altered in a specific and desired manner when compared to the wild-type protein.

Abstract: The invention relates to the genetic modification of plants, particularly to the expression of P-glycoprotein genes in transformed plants. Nucleotide sequences for the Br2 gene encoding a P-glycoprotein of maize and methods for their use are provided. The sequences find use in modifying the growth of plants.

Abstract: The invention provides a method to identify a plurality of plant promoters having a particular characteristic as well as the sequence of promoters having one of those characteristics.

Abstract: Disclosed are polynucleotide and polypeptide sequences involved in or associated with isoprenoid biosynthesis in plants. Also disclosed are uses for such sequences.

Abstract: The present invention relates to the use of a variety of methods for generating functional thioredoxin reductase variants in which at least one physical, chemical or biological property of the variant is altered in a specific and desired manner when compared to the wild-type protein.

Abstract: The present invention is drawn to methods and compositions for suppressing cell death in plants. Specifically, novel proteins and genes are provided for use in plant transformation. The proteins and genes are useful for activating disease resistance, enhancing plant cell transformation efficiency, engineering herbicide resistance, genetically targeting cell ablations, and other methods involving the regulation of cell death in plants.

Abstract: The invention provides a method to identify genes that are modulated by posttranscriptional gene silencing as well as regulatory elements and methods to modulate gene expression by posttranscriptional gene silencing.