Abstract: A cough detection, analysis, and communication platform may be provided. The platform may comprise methods, systems, and a devices for detecting, analyzing, and communicating cough detection data. A cough detection device may comprise at least one microphone and analytic firmware used to employ methods of detecting, analyzing, and communicating the cough detection data. The analytic software may be updated to use the appropriate algorithms for an individual or corresponding demographic based on, for example, age and disease, with abnormal cough frequency components, abnormal cough frequency profiles, and alert thresholds. The cough detection device may be configured to communicate cough detection data to a server. The server, in turn, may be operative to process and communicate the data to a third party, such as, for example, a physician. Systems may further be operative to provide a user interface (e.g., mobile or web applications) for interfacing with the platform.

Abstract: A cough detection, analysis, and communication platform may be provided. The platform may comprise methods, systems, and a devices for detecting, analyzing, and communicating cough detection data. A cough detection device may comprise at least one microphone and analytic firmware used to employ methods of detecting, analyzing, and communicating the cough detection data. The analytic software may be updated to use the appropriate algorithms for an individual or corresponding demographic based on, for example, age and disease, with abnormal cough frequency components, abnormal cough frequency profiles, and alert thresholds. The cough detection device may be configured to communicate cough detection data to a server. The server, in turn, may be operative to process and communicate the data to a third party, such as, for example, a physician. Systems may further be operative to provide a user interface (e.g., mobile or web applications) for interfacing with the platform.

Abstract: A cough detection, analysis, and communication platform may be provided. The platform may comprise methods, systems, and devices for detecting, analyzing, and communicating cough detection data. A cough detection device may comprise at least one microphone and analytic firmware used to employ methods of detecting, analyzing, and communicating the cough detection data. The analytic software may be updated to use the appropriate algorithms for an individual or corresponding demographic based on, for example, age and disease, with abnormal cough frequency components, abnormal cough frequency profiles, and alert thresholds. The cough detection device may be configured to communicate cough detection data to a server. The server, in turn, may be operative to process and communicate the data to a third party, such as, for example, a physician. Systems may further be operative to provide a user interface (e.g., mobile or web applications) for interfacing with the platform.

Abstract: A cough detection, analysis, and communication platform may be provided. The platform may comprise methods, systems, and a devices for detecting, analyzing, and communicating cough detection data. A cough detection device may comprise at least one microphone and analytic firmware used to employ methods of detecting, analyzing, and communicating the cough detection data. The analytic software may be updated to use the appropriate algorithms for an individual or corresponding demographic based on, for example, age and disease, with abnormal cough frequency components, abnormal cough frequency profiles, and alert thresholds. The cough detection device may be configured to communicate cough detection data to a server. The server, in turn, may be operative to process and communicate the data to a third party, such as, for example, a physician. Systems may further be operative to provide a user interface (e.g., mobile or web applications) for interfacing with the platform.

Abstract: A method for imaging a volume of tissue in a scan region, including: emitting, from transmitting transducers, acoustic waveforms toward the volume of tissue; detecting, with detecting transducers, a plurality acoustic signals derived from acoustic waveforms interacting with the volume of tissue; generating from the detected acoustic signals a plurality of variable attenuation maps, in which each variable attenuation map corresponds to acoustic signals detected by a respective detecting transducer and includes a plurality of variable attenuation coefficients mapped to the scan region; modifying at least a portion of the detected acoustic signals based on one or more variable attenuation maps; and generating a reflection rendering of the volume of tissue based on the modified acoustic signals.

Abstract: A computer-implemented method and system are provided for assisting a plurality of patients manage chronic health conditions.

Abstract: A system for the detection of ligands comprising at least one receptor and an amplification mechanism coupled to the receptor wherein an amplified signal is produced as a result of receptor binding a ligand. Examples of suitable amplification mechanisms include antibody-embedded liquid crystalline materials; use of alpha-2-macroglobulin to encage an enzyme, whereby the enzyme is separated from its substrate by an receptor; and a receptor engineered to inhibit the active of site of an enzyme only in the absence of a ligand. Also provided are methods for the automatic detection of ligands.

Abstract: A prosthetic venous valve includes a frame and leaflets. The frame includes: (i) a generally hollow base disposed at a blood inflow end; (ii) a plurality of struts connected with the base and extending generally parallel to a direction of forward flow of blood from the generally hollow base to a blood outflow end; and (iii) inwardly oriented flanges disposed at the blood outflow ends of the struts. The leaflets are disposed in gaps between the struts and are supported by the frame. The leaflets are arranged to close into the vein lumen to substantially seal against backflow of blood from the blood outflow end to the blood inflow end. The inwardly oriented flanges of the struts enhance the sealing.

Abstract: A system for the detection of ligands comprising at least one receptor and an amplification mechanism coupled to the receptor wherein an amplified signal is produced as a result of receptor binding a ligand. Examples of suitable amplification mechanisms include antibody-embedded liquid crystalline materials; use of alpha-2-macroglobulin to encage an enzyme, whereby the enzyme is separated from its substrate by an receptor; and a receptor engineered to inhibit the active of site of an enzyme only in the absence of a ligand. Also provided are methods for the automatic detection of ligands.

Abstract: A system for the detection of ligands comprising at least one receptor and an amplification mechanism coupled to the receptor wherein an amplified signal is produced as a result of receptor binding a ligand. Examples of suitable amplification mechanisms include antibody-embedded liquid crystalline materials; use of alpha-2-macroglobulin to encage an enzyme, whereby the enzyme is separated from its substrate by an receptor; and a receptor engineered to inhibit the active of site of an enzyme only in the absence of a ligand. Also provided are methods for the automatic detection of ligands.

Abstract: A system for the detection of ligands comprising at least one receptor and an amplification mechanism coupled to the receptor wherein an amplified signal is produced as a result of receptor binding a ligand. Examples of suitable amplification mechanisms include antibody-embedded liquid crystalline materials; use of alpha-2-macroglobulin to encage an enzyme, whereby the enzyme is separated from its substrate by an receptor; and a receptor engineered to inhibit the active of site of an enzyme only in the absence of a ligand. Also provided are methods for the automatic detection of ligands.

Abstract: A system for the detection of ligands comprising at least one receptor and an amplification mechanism coupled to the receptor wherein an amplified signal is produced as a result of receptor binding a ligand. Examples of suitable amplification mechanisms include antibody-embedded liquid crystalline materials; use of alpha-2-macroglobulin to encage an enzyme, whereby the enzyme is separated from its substrate by an receptor; and a receptor engineered to inhibit the active of site of an enzyme only in the absence of a ligand. Also provided are methods for the automatic detection of ligands.

Abstract: A liquid electrostatic developer includes a toner which is made from a halogenated resin, a thermoplastic resin and a colorant. Preferably the halogenated resin is a fluorinated resin. Optionally, a charge adjuvant may be present. The liquid electrostatic developer is prepared by a process wherein the halogenated resin, the thermoplastic resin, the optional colorant and the optional charge adjuvants are melt blended to form a mixture. This mixture is ground at a cold temperature, and subsequently charged with a charge director. The toner used in the liquid electrostatic developer formed by this process has excellent thermoplastic and electrical properties and provides a developer with excellent imaging characteristics.

Abstract: Process for reversal development of a latent electrostatic image in a layer on a conductive support by developing with an electrostatic developer having electrostatically charged toner particles by(a) generating imagewise areas in the layer having different rates of charge decay and/or charge acceptance,(b) charging the layer,(c) allowing formation of an electrostatic image corresponding to the imagewise generated areas by differential charge decay and/or charge acceptance,(d) creating an electrical field to attract toner particles preferentially to the areas of lesser charge, and(e) developing the areas of lesser charge with electrostatically charged toner particles having the same polarity as that of the charged layer.The developed image can be transferred to a receptor surface, e.g., paper. The process is useful with many type photosensitive masters in preparing reversal images with the use of only one master, toner and film original.

Abstract: Process for preparation of high resolution image exposing imagewise a photopolymerizable element having a removable cover sheet and a conductive support or a temporary support which is replaced by a conductive support, stripping the cover sheet and laminating the imagewise exposed photopolymerizable layer to a second exposed photopolymerizable layer on a temporary support, removing the temporary support, charging electrostatically the exposed photopolymerizable layers, developing, e.g., liquid electrostatic developer or dry toner developer, and optionally transferring the developed image to a receptor surface, e.g., paper. The process is useful in preparing multiple copies in more than one version, e.g., logos, headlines, corrections, etc.

Abstract: Process for preparation of a correct reading image comprising(A) exposing imagewise to actinic radiation a photopolymerizable electrographic element comprising in order a temporary support, photopolymerizable layer, and a strippable cover sheet, the exposure being through the cover sheet;(B) stripping the cover sheet;(C) laminating the exposed surface of the photopolymerizable layer to a conductive substrate;(D) peeling off the temporary support;(E) charging electrostatically the exposed photopolymerizable layer to form a latent image of electrostatic charge on the exposed areas;(F) toning the electrostatically charged exposed imaged areas; and(G) transferring the toned image to a receptor support.Multiple copies can be produced with a single exposure. Overlay or surprint proofs can be prepared.

Abstract: A positive-working liquid electrostatic developer consisting essentially of(A) nonpolar liquid having a Kauri-butanol value of less than 30, present in major amount;(B) thermoplastic resin of an ethylene homopolymer or copolymer of ethylene and at least one other monomer, the resin having as a substituent thereon an ester, ester having substitutents, e.g., hydroxyl, carboxyl, amine, alkyl; an amide, amide having substituents, e.g., hydroxyl, carboxyl, amine, alkyl; or acid halide of a carboxylic acid, the resin being in particulate form having an average particle size by area of less than 10 .mu.m; and(C) nonpolar liquid soluble ionic or zwitterionic compound.Several procedures can be used to prepare the developer, e.g., using toner concentrate, modifying a thermoplastic resin before developer is prepared. Pigments and adjuvants can be present in the developer which is useful in copying, making proofs including digital proofs, lithographic printing plates and resists.